Browsing Det helsevitenskapelige fakultet by Title

Now showing items 4969-4988 of 10115

    • Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome 

      Berg, Leif Kyrre; Goll, Rasmus; Fagerli, Erik; Ludviksen, Judith K; Fure, Hilde; Odd Sverre, Moen; Sørbye, Sveinung; Mollnes, Tom Eirik; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-24)
      Background: It has been proposed that irritable bowel syndrome (IBS) is a low-grade mucosal inflammatory disease. <p> <p>Objective: To characterize the intestinal inflammatory profile in IBS patients with or without fructose intolerance.<p> <p>Design: Patients referred to colonoscopy with IBS complaints were screened for participation. IBS patients diagnosed according to the Rome II criteria ...

    • Intimate partner violence and its association with mental health problems: The importance of childhood violence – The SAMINOR 2 Questionnaire Survey 

      Eriksen, Astrid; Melhus, Marita; Jacobsen, Bjarne K.; Schei, Berit; Broderstad, Ann-Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-30)
      Aims: This study aims to estimate the prevalence of intimate partner violence (IPV) and its association with psychological distress and symptoms of post-traumatic stress (PTS) among Sami and non-Sami and to explore whether the association between IPV and mental health is modified by exposure to childhood violence (CV). These issues are scarcely studied among the Sami. Methods: This study was based ...

    • Intra- and inter-rater reliability of the Mini-Balance Evaluation Test (Mini-BESTest) in individuals with stroke 

      Dahl, Stine Susanne Haakonsen (Master thesis; Mastergradsoppgave, 2012-05-15)
      ABSTRACT Background: Mini-Balance Evaluation Systems Test (Mini-BESTest) is a new and promising measure for evaluation of dynamic balance, but intra- and inter-rater reliability in individuals with stroke have not yet been examined. Objective: The aim of this study was to assess the within raters’ (intra-rater) and between raters’ (inter-rater) reliability of the Mini-BESTest in adults with stroke. ...

    • Intra- and interobserver variation in lung sound classification. Effect of training. 

      Grunnreis, Fredrik Ostad (Master thesis; Mastergradsoppgave, 2016-05-31)
      This study explores how last year medical students at the University of Tromsø, the Arctic University of Norway, interpret and describe different lung sounds. This is done by measuring intra- and interobserver variation in agreement among 16 students, when reporting abnormal lung sounds after listening to audio recordings. Agreement with a reference standard is included, and testing of effect on ...

    • Intra-cellular to inter-organ mitochondrial communication in striated muscle in health and disease 

      Boardman, Neoma Tove; Wüst, Rob C.I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-02)
      Mitochondria sense both biochemical and energetic input in addition to communicating signals regarding the energetic state of the cell. Increasingly, these signaling organelles are recognized as key for regulating different cell functions. This review summarizes recent advances in mitochondrial communication in striated muscle, with specific focus on the processes by which mitochondria communicate ...

    • Intracellular gelatinolytic activity in mouse tissues 

      Solli, Ann Iren (Master thesis; Mastergradsoppgave, 2011-09-12)
      Matrix metalloproteinases have traditionally been thought to act only extracellulary. However, increasing evidence has revealed intracellular localization as well as several alternative substrates and novel biological roles for these proteinases. The aims of this master thesis were to map intracellular localization of MMP-2 and MMP-9 in different tissues from mouse, determine if detected enzymes ...

    • Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers 

      Hadler-Olsen, Elin Synnøve; Solli, Ann Iren; Hafstad, Anne Dragøy; Winberg, Jan-Olof; Uhlin-Hansen, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-09-29)
      Matrix metalloproteinase 2 (MMP-2) is a proteolytic enzyme implicated in motility, differentiation, and regeneration of skeletal muscle fibers through processing of extracellular substrates. Although MMP-2 has been found to be localized intracellularly in cardiomyocytes where the enzyme is thought to contribute to post-ischemic loss of contractility, little is known about intracellular MMP-2 activity ...

    • Intracellular Transposition and Capture of Mobile Genetic Elements following Intercellular Conjugation of Multidrug Resistance Conjugative Plasmids from Clinical Enterobacteriaceae Isolates 

      Tansirichaiya, Supathep; Goodman, Richard N.; Guo, Xinyu; Bulgasim, Issra; Samuelsen, Ørjan; Al-Haroni, Mohammed; Roberts, Adam P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-19)
      Mobile genetic elements (MGEs) are often associated with antimicrobial resistance genes (ARGs). They are responsible for intracellular transposition between different replicons and intercellular conjugation and are therefore important agents of ARG dissemination. Detection and characterization of functional MGEs, especially in clinical isolates, would increase our understanding of the underlying ...

    • Intrakranielle gliomer hos personer over 15 år i Nord-Norge i perioden 1986-2001. 

      Bjarghov, Steinar; Stølen, Stian Bergseng (Master thesis; Mastergradsoppgave, 2002-08-30)

    • Intramuscular uptake of tranexamic acid during haemorrhagic shock in a swine model 

      Bakke, Håkon Kvåle; Fuskevåg, Ole Martin; Nielsen, Erik Waage; Dietrichs, Erik Sveberg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-18)
      Background: Tranexamic acid (TXA) reduce mortality in bleeding trauma patients, with greater efect if administered early. Serum concentrations above 10 µg/mL are considered sufcient to inhibit fbrinolysis. Normally administered intravenously (i.v.), TXA can also be administered intramuscularly (i.m.). This could be advantageous in low resource and military settings, if sufcient serum concentrations ...

    • Intraoperative swept-source OCT–based corneal topography for measurement and analysis of stromal surface after epithelial removal 

      Zhou, Wen; Reinstein, Dan Z.; Archer, Timothy J.; Chen, Xiangjun; Utheim, Tor Paaske; Feng, Yue; Stojanovic, Aleksandar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-01)
      <p>PURPOSE: To assess intraoperative stromal topography measurements using swept-source optical coherence tomography (OCT)–based topography/tomography after epithelial removal and to analyze the epithelial contribution to the corneal topography and optics. <p>METHODS: This was a prospective series of 22 eyes of 19 patients referred to receive phototherapeutic keratotomy (PTK) for treatment of ...

    • Intraregional hospital outbreak of OXA-244-producing Escherichia coli ST38 in Norway, 2020 

      Lindemann, Paul Christoffer; Pedersen, Torunn Annie; Oma, Dorthea Hagen; Janice, Jessin; Grøvan, Fredrik; Chedid, Ghantous Milad; Hafne, Liv Jorunn; Josefsen, Ellen Haldis; Kacelnik, Oliver; Sundsfjord, Arnfinn; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-06)
      Infections with OXA-244-carbapenemase-producing Escherichia coli with sequence type (ST)38 have recently increased in Europe. Due to its low-level activity against carbapenems, OXA-244 can be difficult to detect. Previous assessments have not revealed a clear source and route of transmission for OXA-244-producing E. coli, but there are indications of non-healthcare related sources and community ...

    • Intrathoracic Breast Transposition: A New Method in the Treatment of Bronchopleural Fistula and Empyema 

      de Weerd, Louis; Endresen, Petter Cappelen; Numan, Anmar; Weum, Sven (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      A bronchopleural fistula (BF) is a life-threatening complication. Optimal management of a BF is still debated although surgery remains the preferred treatment. Usually, the fistula is a result of inadequate healing at the bronchial stump after pneumonectomy. Successful closure of a BF after pneumonectomy depends on evacuation of empyema, coverage of the suture line after fistula closure with ...

    • Intrauterine progestin therapy as a new approach to premalignant endometrial polyps: A prospective observational study 

      Sletten, Elise Thoresen; Arnes, Marit; Vereide, Anne Beate; Ørbo, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09)
      Background/Aim: Endometrial hyperplastic polyps (EHP) may progress to endometrial carcinoma (EC) if left untreated. We aimed to prospectively investigate the efficacy of the low-dose levonorgestrel intrauterine system (LNG-IUS) as therapy for EHP with malignant potential. Patients and Methods: In total, 37 women with EHP underwent therapy with LNG-IUS containing 13.5 mg levonorgestrel for six months ...

    • Intravenous thrombolytic treatment and endovascular thrombectomy for ischaemic wake-up stroke 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-01)
      <b><p>Background</b> About one in five strokes occur during sleep (wake-up stroke). People with wake-up strokes have previously been considered to be ineligiblefor thrombolytic treatment because the time of stroke onset is unknown. However, recent studies suggest benefit from recanalisationtherapies in selected patients. <b><p>Objectives</b> To assess the effects of intravenous thrombolysis ...

    • Intravenøs ketamin for behandlingsresistent depresjon: Et scoping review 

      Lilleng, Tora; Forfang, Marie Charlotte (Mastergradsoppgave; Master thesis, 2022-12-12)
      Bakgrunn: Depresjon er blant de mest prevalente sykdommene i vestlige land. Flere av pasienter med depressive lidelser opplever ikke bedring av tilgjengelige behandlinger, og betegnes som behandlingsresistente. Lave doser intravenøs ketamin har vist å gi rask antidepressiv effekt kort tid etter infusjon, og det publiseres et stigende antall studier om ketamins virkning. Vi gjennomførte et scoping ...

    • Intra‐arterial blood pressure traits during and after heavy resistance exercise in healthy males 

      Heitmann, Kim Arne; Dalen, Håvard; Gundersen, Guri Holmen; Ingvaldsen, Rolf Petter; Welde, Boye (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-29)
      This randomized within‐subjects crossover‐designed study evaluated intra‐arterial blood pressure (BP) traits in seven healthy males (24 ± 1 years) during heavy resistance exercise (HRE) to failure (10 × 5 repetitions, 5RES) and not to failure (10 × 3 repetitions, 3RES), both at 5RM load. By combining few repetitions, avoidance of Valsalva maneuver, and restricting the duration of each contraction, ...

    • Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood 

      Konrath, Sandra; Mailer, Reiner K.; Beerens, Manu; Englert, Hanna; Frye, Maike; Kuta, Piotr; Preston, Roger J. S.; Maas, Coen; Butler, Lynn; Roest, Mark; de Laat, Bas; Renné, Thomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-28)
      Calibrated Automated Thrombography (CAT) is a versatile and sensitive method for analyzing coagulation reactions culminating in thrombin generation (TG). Here, we present a CAT method for analyzing TG in murine whole blood by adapting the CAT assay used for measuring TG in human plasma. The diagnostically used artificial and physiologic factor XII (FXII) contact activators kaolin, ellagic acid ...

    • Introducing dental local anaesthesia using a standardized cognitive behavioural technique 

      Vestjord, Maria; Kjøløymo, Tina; Nerdal, Anne Marte (Master thesis; Mastergradsoppgave, 2012-05-29)
      A major dilemma is that pain free dental treatment using local anaesthesia (LA) is of main importance for avoiding dental fear and anxiety (DFA) at the same time as intraoral injections are strongly associated with DFA. Well-educated dentists and dental hygienists, with a variety of techniques and approaches available, are important to give the patient receiving LA a perception of control. The purpose ...

    • Introducing Lightweight IT – A Way to Build Flexibility for Healthcare Organizations? 

      Severinsen, Gro-Hilde; Silsand, Line; Malm-Nicolaisen, Kristian; Pedersen, Rune; Ellingsen, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      The paper addresses socio technical relations of implementing a lightweight IT app in Norway. The focus is on how such technology will influence the possibilities for an organization connected to a large-scale heavyweight IT infrastructure to provide more rapid changes in line with healthcare worker’s needs. The research question is therefore: How can lightweight IT support rapid organizational ...