Viser treff 690-709 av 10096

    • Automatic measurements of left ventricular volumes and ejection fraction by artificial intelligence: clinical validation in real time and large databases 

      Olaisen, Sindre Hellum; Smistad, Erik; Espeland, Torvald; Hu, Jieyu; Pasdeloup, David Francis Pierre; Østvik, Andreas; Aakhus, Svend; Rösner, Assami; Malm, Siri; Stylidis, Michael; Holte, Espen; Grenne, Bjørnar Leangen; Løvstakken, Lasse; Dalen, Håvard (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-26)
      Aims - Echocardiography is a cornerstone in cardiac imaging, and left ventricular (LV) ejection fraction (EF) is a key parameter for patient management. Recent advances in artificial intelligence (AI) have enabled fully automatic measurements of LV volumes and EF both during scanning and in stored recordings. The aim of this study was to evaluate the impact of implementing AI measurements on acquisition ...
    • Autonomi blant sykehjemsbeboere 

      Rajalingam, Parabaran (Master thesis; Mastergradsoppgave, 2014-05-07)
      Forskning om livskvalitet på sykehjem viser at det er viktig for beboere å bestemme i hverdagen i saker som angår dem selv. På sykehjem virker det mer naturlig å snakke om medbestemmelse isteden for selvbestemmelse. Studiens hensikt har vært å belyse fem sykepleieres opplevelser og erfaringer knyttet til beboeres autonomi på sykehjem.For å finne svar på problemstillingen ble fem sykepleiere som ...
    • Autonomi og meningsdannelse i klinisk resonnering - En kvalitativ intervjustudie om fysioterapeuters erfaringer med å anvende fysioterapitilnærmingen ICoreDIST når det kommer til klinisk resonnering og valg i fysioterapi 

      Rubach, Cathrine (Mastergradsoppgave; Master thesis, 2022-05-04)
      Sammendrag Hensikt og bakgrunn: Denne studien har til hensikt å tilføre fagfeltet ny kunnskap gjennom ny innsikt i fysioterapeuters opplevelse av å bruke fysioterapitilnærmingen ICoreDIST for personer med hjerneslag i subakutt fase når det kommer til klinisk resonnering og valg i fysioterapi. Bakgrunnen for valgt tema og problemstilling er pasientgruppens store utbredelse og manglende forskning ...
    • Autonomous or controlled self-regulation, that is the question: A self-determination perspective on the impact of commuting on employees’ domain-specific functioning 

      Gerpott, Fabiola H.; Rivkin, Wladislaw; Unger, Dana (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-01)
      The few studies that have considered psychological processes during the commute have drawn an ambiguous picture, with some emphasizing the negative and others the positive consequences of commuting. Drawing on self-determination theory, we develop a framework that expands on the costs and benefits of commuting for employees’ subsequent domain-related functioning at work and home. Specifically, we ...
    • Autophagy : investigating the possible interaction between cochaperone BAG3 and the Ubiquitin-binding protein p62 

      Moumakwa, Cheneso (Master thesis; Mastergradsoppgave, 2010-09-15)
      Introduction: Autophagy is an evolutionary conserved intracellular catabolic process which involves the degradation of a cell’s own components. The degradation happens in two (2)main pathways: the ubiquitin-proteasome system that degrades short-lived proteins, and the autophagy system that degrades long-lived proteins and damaged organelles. There are three known different pathways of autophagy ...
    • Autophagy and endocytosis – interconnections and interdependencies 

      Birgisdottir, Åsa birna; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-22)
      Autophagy and endocytosis are membrane-vesicle-based cellular pathways for degradation and recycling of intracellular and extracellular components, respectively. These pathways have a common endpoint at the lysosome, where their cargo is degraded. In addition, the two pathways intersect at different stages during vesicle formation, fusion and trafficking, and share parts of the molecular machinery. ...
    • Autophagy in major human diseases 

      Klionsky, Daniel J.; Petroni, Giulia; Amaravadi, Ravi K; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine M K; Choi, Mary E; Chu, Charleen T.; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Gewirtz, David A.; Green, Douglas R.; Hansen, Malene; Jäättelä, Marja; Johansen, Terje; Juhász, Gábor; Karantza, Vassiliki; Kraft, Claudine; Kroemer, Guido; Ktistakis, Nicholas T; Kumar, Sharad; López-Ótin, Carlos; Macleod, Kay F; Madeo, Frank; Martinez, Jennifer; Melendez, Alicia; Mizushima, Noboru; Münz, Christian; Penninger, Josef M.; Perera, Rushika M.; Piacentini, Mauro; Reggiori, Fulvio; Rubinsztein, David C.; Ryan, Kevin M.; Sadoshima, Junichi; Santambrogio, Laura; Scorrano, Luca; Simon, Hans-Uwe; Simon, Anna Katharina; Simonsen, Anne; Stolz, Alexandra; Tavernarakis, Nektarios; Tooze, Sharon A.; Yoshimori, Tamotsu; Yuan, Junying; Yue, Zhenyu; Zhong, Qing; Galluzzi, Lorenzo; Pietrocola, Federico (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-30)
      Autophagy is a core molecular pathway for the preservation of cellular and organismal homeostasis. Pharmacological and genetic interventions impairing autophagy responses promote or aggravate disease in a plethora of experimental models. Consistently, mutations in autophagy-related processes cause severe human pathologies. Here, we review and discuss preclinical data linking autophagy dysfunction ...
    • Autoregulation of Cerebral Blood Flow During 3-h Continuous Cardiopulmonary Resuscitation at 27°C 

      Valkov, Sergei; Nilsen, Jan Harald; Mohyuddin, Rizwan; Schanche, Torstein Lindahl; Kondratyev, Timofey; Sieck, Gary C.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-09)
      Introduction: Victims of accidental hypothermia in hypothermic cardiac arrest (HCA) may survive with favorable neurologic outcome if early and continuous prehospital cardiopulmonary resuscitation (CPR) is started and continued during evacuation and transport. The efficacy of cerebral autoregulation during hypothermic CPR is largely unknown and is aim of the present experiment.<p> <p>Methods: ...
    • Autotransplantasjon av visdomstenner. Litteraturgjennomgang og retrospektiv undersøkelse. 

      Tønne, Synne Marie (Master thesis; Mastergradsoppgave, 2014)
      Bakgrunn: Denne masteroppgaven fokuserer på autotransplantasjon av visdomstenner med lukket apex hos voksne pasienter, og hvorvidt dette er et godt behandlingsalternativ for erstatning av hovedsakelig tapt første eller andre molar. Mål: Presentere autotransplantasjon som behandling i en allmenntannleges praksis, med fokus på den voksne pasient og bruk av modne visdomstenner som ...
    • Availability and Affordability of Medicines for the Treatment of Cardiovascular Diseases in Pharmacies in Six Regions of the Russian Federation 

      Imaeva, Asiia E; Balanova, Yulia A; Kontsevaya, Anna V; Kapustina, Anna V; Duplyakov, Dmitry V.; Malysheva, Olga H; Osipova, Irina V.; Petrichko, Tatiana A; Kropanin, Georgiy I; Kasimov, Riza A; Leon, David Adrew; McKee, Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      <i>Aim</i>: To evaluate the availability and affordability of medicines used to treat of cardiovascular diseases (CVD) in several regions of the Russian Federation with different climatic, geographic, economic and demographic characteristics.<p> <p><i>Material and methods</i>: The study was conducted in 6 regional capitals, chosen to differ in geographically, economically, and demographically. ...
    • AvaLife—A New Multi-Disciplinary Approach Supported by Accident and Field Test Data to Optimize Survival Chances in Rescue and First Aid of Avalanche Patients 

      Genswein, Manuel; Macias, Darryl; McIntosh, Scott; Reiweger, Ingrid; Hetland, Audun; Paal, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-26)
      Snow sports in the backcountry have seen a steep increase in popularity, and therefore preparedness for efficient companion and organized rescue is important. While technical rescue skills are widely taught, there is a lack of knowledge regarding first aid for avalanche patients. The stressful and time-critical situation for first responders requires a rule-based decision support tool. AvaLife ...
    • Avatars using computer/smartphone mediated communication and social networking in prevention of sexually transmitted diseases 

      Gabarron, Elia; Serrano, Jose Artur F S Vale; Wynn, Rolf; Armayones Ruiz, Manuel (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Sexually transmitted diseases (STDs), especially the Chlamydia trachomatis bacterial infection, a common cause of infertility, are highly prevalent in developed countries, and a worrying problem in North Norway, where the incidence of chlamydia twice the Norwegian average. Seventy percent of reported chlamydia cases are found in people below 25 years of age, and although its spread could be controlled ...
    • Avdelingslederes erfaringer med å behandle avviksmeldinger på sykehjem 

      Andersen, Ingvil Birkelund (Master thesis; Mastergradsoppgave, 2014-10-01)
      SAMMENDRAG Bakgrunn: I dag bor det over 40 000 pleietrengende eldre på norske sykehjem. Statistisk sett har de fem diagnoser hver. Avdelingslederes formelle ansvar er påse at pleietilbud er av god og forsvarlig karakter. En måte å kontrollere kvalitet og pasienters sikkerhet på er gjennom avviksprosedyren. Denne prosedyren er en del av kommunenes interne kontrollsystem. Formål: I forskningssammenheng ...
    • Avoidable cancer cases in the Nordic countries - The impact of overweight and obesity 

      Andersson, Therese M.-L.; Weiderpass, Elisabete; Engholm, Gerda; Lund, Anne-Sofie Q.; Ólafsdóttir, Elínborg Jóna; Pukkala, Eero; Stenbeck, Magnus; Storm, Hans (Journal article; Tidsskriftartikkel, 2017-05-03)
      Background: <br>Several types of cancers are causally linked to overweight and obesity which are increasing in the Nordic countries. The aim of this study was to quantify the proportion of the cancer burden linked to overweight and obesity in the Nordic countries and estimate the potential for cancer prevention.<br> Methods: <br>Under different prevalence scenarios of overweight and obesity, ...
    • Avvik i legemiddelhåndtering ved sykehus, Universitetssykehuset Nord-Norge. Sårbare områder, meldekultur og forslag til forbedringstiltak 

      Ademi, Adelina (Master thesis; Mastergradsoppgave, 2017-05-15)
      BAKGRUNN: Avvik i legemiddelhåndteringen kan assosieres med lengre sykehusopphold og høyere helsekostnader, noe som medfører høy belastning for pasient, pårørende og helsevesen. Avviksrapportering belyser hvor det er læringspotensial og behov for forbedringstiltak. Avvik i helsevesenet skal innrapporteres og brukes som et ledd for å forbedre pasientsikkerheten, forebygge kvalitetssvikt og hindre ...
    • Avviksrapportering i sykehus – et godt verktøy for læring? En kvalitativ studie om klinikernes erfaringer om det interne avvikssystemet på et norsk sykehus 

      Johansen, Jørgen Breivik (Master thesis; Mastergradsoppgave, 2023-05-31)
      Bakgrunn: Norske helseforetak er pålagt å drive kvalitetsforbedring for å bedre pasientsikkerhet ved norske sykehus. Det interne rapporteringssystemet er det viktigste formelle verktøyet for dette på lokalt nivå. Formål: studiens hensikt er å undersøke hvorvidt det interne avviksrapporteringssystemet bidrar til kvalitetsforbedring, og hvilke utfordringer helsepersonellet identifiserer ved bruk av ...
    • Avviksregistreringens betydning for god sykepleie 

      Larsen, Lill Sverresdatter (Master thesis; Mastergradsoppgave, 2011-05-18)
      Studien har tatt utgangspunkt i de store rapporterte mørketall vedrørende uønskede hendelser og manglende avviksregistrering i spesialisthelsetjenesten. Problemet er utdypet i tidligere studier som i hovedsak har hatt fokus på strukturelle og kulturelle forhold. Denne studien har vektlagt hva sykepleierne gjør når de erfarer avvik. Et premiss har vært at oppfatningen av eget ansvar vises gjennom ...
    • AXL inhibition improves BRAF-targeted treatment in melanoma 

      Nyakas, Marta Sølvi; Fleten, Karianne Giller; Haugen, Mads Haugland; Engedal, Nikolai; Sveen, Christina; Farstad, Inger Nina; Flørenes, Vivi Ann; Prasmickaite, Lina; Mælandsmo, Gunhild Mari; Vasiliauskaite, Kotryna (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      More than half of metastatic melanoma patients receiving standard therapy fail to achieve a long-term survival due to primary and/or acquired resistance. Tumor cell ability to switch from epithelial to a more aggressive mesenchymal phenotype, attributed with AXL<sup>high</sup> molecular profle in melanoma, has been recently linked to such event, limiting treatment efcacy. In the current study, ...
    • Azithromycin versus placebo for the treatment of HIV-associated chronic lung disease in children and adolescents (BREATHE trial): study protocol for a randomised controlled trial 

      Gonzalez-Martinez, Carmen; Kranzer, Katharina; McHugh, Grace; Corbett, Elizabeth L.; Mujuru, Hilda A.; Nicol, Mark P; Rowland-Jones, Sarah; Rehman, Andrea M.; Gutteberg, Tore Jarl; Flægstad, Trond; Odland, Jon Øyvind; Ferrand, Rashida (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-28)
      Background<br> Human immunodeficiency virus (HIV)-related chronic lung disease (CLD) among children is associated with substantial morbidity, despite antiretroviral therapy. This may be a consequence of repeated respiratory tract infections and/or dysregulated immune activation that accompanies HIV infection. Macrolides have anti-inflammatory and antimicrobial properties, and we hypothesised that ...
    • Azithromycin-liposomes as a novel approach for localized therapy of cervicovaginal bacterial infections 

      Vanic, Zeljka; Rukavina, Zora; Manner, Suvi; Fallarero, Adyary; Uzelac, Lidija; Kralj, Marijeta; Amidzic Klaric, Danijela; Bogdanov, Anita; Raffai, Timea; Virok, Deszo Peter; Filipovic-Grcic, Jelena; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-30)
      <p><i>Background - </i>Efficient localized cervicovaginal antibacterial therapy, enabling the delivery of antibiotic to the site of action at lower doses while escaping systemic drug effects and reducing the risk of developing microbial resistance, is attracting considerable attention. Liposomes have been shown to allow sustained drug release into vaginal mucosa and improve delivery of antibiotics ...