Denne masteroppgaven fokuserer på utfordringer og begrensninger ved å innføre videokonferanseteknologi i hjemmebasert omsorg. Det er gjort en avgrensning slik at det er arbeidsformen tilsyn som studeres. Studien er gjennomført i en kommune der slik teknologi ikke er tatt i bruk i forbindelse med omsorgsarbeid. Det tas utgangspunkt i sykepleieres erfaringer med å utøve tilsyn samt deres tanker og ...

Det å leve med en kreftsyk mamma eller pappa og miste henne eller han av sykdommen er en altomfattende livshendelse som griper om seg i tid og rom. Det å miste en forelder vil være noe av det verste som kan skje i et barns liv. Hensikten med studien er å tilegne innsikt og utdypende kunnskap om barn som pårørende og etterlatte og deres behov for støtte. Kunnskap og viten vil frembringes ved hjelp ...

The host is protected by pattern recognition systems, including complement and TLRs, which are closely cross-talking. If improperly activated, these systems might induce tissue damage and disease. Inhibition of single downstream proinflammatory cytokines, such as TNF, IL-1β, and IL-6, have failed in clinical sepsis trials, which might not be unexpected, given the substantial amounts of mediators ...

It is well established that a family of dual-specificity MAP kinase phosphatases (MKPs) play key roles in the regulated dephosphorylation and inactivation of MAP kinase isoforms in mammalian cells and tissues. MKPs provide a mechanism of spatiotemporal feedback control of these key signalling pathways, but can also mediate crosstalk between distinct MAP kinase cascades and facilitate interactions ...

There is conflicting evidence as to whether duration of lactation may decrease the risk of subsequent development of an unfavorable maternal metabolic profile, including overweight and obesity. We hypothesized that duration of lactation is associated with a more favorable metabolic profile and healthier anthropometric measurements. Ninety-eight parous women were studied from the Norwegian EBBAI-study ...

Background - ‘Most patients want to die at home’ is a familiar statement in palliative care. The rate of home deaths is therefore often used as a success criterion. However, providing palliative care and enabling patients to die at home in rural and remote areas may be challenging due to limited health care resources and geographical factors. In this study we explored health care professionals’ ...

<p><i>Purpose:</i> The goal was to investigate potential roles played by vitamin D in the regulation of joint cartilage biology. We studied the expression of two central elements of vitamin D metabolism, namely the vitamin D receptor and its converting enzyme 1­α­hydroxylase in human knee cartilage and chondrocytes. <p><i>Methods and Materials:</i> Expression of receptor and enzyme was determined ...

Pregnancy causes significant changes in maternal circulation and cardiac function. In healthy pregnancy the blood volume, heart rate, stroke volume and cardiac output are known to increase and these physiological alterations are largely complete by mid-gestation. Investigation into cardiovascular response to dynamic changes in the loading condition of heart during pregnancy might contribute to better ...

ADP-ribosylation is a posttranslational modification catalyzed in cells by ADP-ribosyltransferases (ARTD or PARP enzymes). The ARTD family consists of 17 members. Some ARTDs modify their substrates by adding ADP-ribose in an iterative process, thereby synthesizing ADP-ribose polymers, the best-studied example being ARTD1/PARP1. Other ARTDs appear to mono-ADP-ribosylate their substrates and are unable ...

Most sporadic colorectal cancers (CRCs) develop from preformed adenomas. Cytokines are involved in the transition from adenoma to CRC. Interleukin-33 (IL-33) is a newly discovered proinflammatory cytokine belonging to the IL-1 cytokine family and involved in the development of chronic inflammation and cancer. The aim of this study was to evaluate the dynamics of the IL-33/ST2 axis during the sequence ...