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Early death after palliative radiation treatment: 30-, 35- and 40-day mortality data and statistically robust predictors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-03)Background This study analyzed mortality after radiotherapy for bone metastases (287 courses). Endpoints such as treatment in the last month of life and death within 30, 35 and 40 days from start of radiotherapy were evaluated.<p> <p>Methods Different baseline parameters including but not limited to blood test results and patterns of metastases were assessed for association with early death. After ... -
Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-27)Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains difficult and AF-related complications cause unacceptable morbidity and mortality even on optimal current therapy. This document summarizes the key outcomes of the 8th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA). Eighty-three ... -
Early diagnosis of abdominal cancer in general practice
(Others; Andre, 2010-02-12) -
Early drinking onset: A study of prevalence and determinants among 13-year-old adolescents in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Early empirical antibiotics and adverse clinical outcomes in infants born very preterm: A population-based cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)Objective The objective of this study was to evaluate the association between empirical antibiotic therapy in the first postnatal week in uninfected infants born very preterm and the risk of adverse outcomes until discharge.<p> <p>Study design Population-based, nationwide registry study in Norway including all live-born infants with a gestational age <32 weeks surviving first postnatal week without ... -
Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor
(Journal article; Tidsskriftartikkel; Peer reviewed; Mastergradsoppgave; Master thesis, 2020-01-10)<i>Background</i> - BK Polyomavirus (BKPyV) causes premature graft failure in 1 to 15% of kidney transplant (KT) recipients. High-level BKPyV-viruria and BKPyV-DNAemia precede polyomavirus-associated nephropathy (PyVAN), and guide clinical management decisions. In most cases, BKPyV appears to come from the donor kidney, but data from biopsy-proven PyVAN cases are lacking. Here, we report the early ... -
Early intervention influences positively quality of life as reported by prematurely born children at age nine and their parents; a randomized clinical trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-22)Background: The Tromsø Intervention Study on Preterms evaluates an early, sensitizing intervention given to parents of prematurely born children (birth-weight < 2000 g). The current study investigated the potential influence of the intervention on children’s self-reported and parental proxy-reported quality of life (QoL) at children’s age of nine. <p>Methods: Participants were randomized to either ... -
Early intervention program reduces stress in parents of preterms during childhood, a randomized controlled trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Early Maladaptive Schemas and Mental Disorders in Adulthood: a Systematic Review and Meta-analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-21)Early maladaptive schemas (EMSs) are broad and pervasive themes regarding oneself and one’s relationships with others originating from adverse childhood experiences. Although the concept of EMSs was initially developed for the treatment of personality disorders, the associations of EMSs with a variety of other mental disorders have been investigated. The goal of the present study was to summarize ... -
Early maladaptive schemas as predictors of maternal bonding to the unborn child
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-11)<p><i>Background - </i>The quality of an expectant mother’s bonding to the fetus has been shown to be associated with important developmental outcomes. Previous studies suggest that bonding quality is predicted by, for example, social support, psychological well-being, and depression. However, little is known regarding the role of maternal cognition in maternal-fetal bonding. Early maladaptive schemas ... -
Early markers of metabolic disease in obesity - A study of postprandial triglycerides, leptin and adiponectin interactions in the view of normal and dysregulated metabolism
(Doctoral thesis; Doktorgradsavhandling, 2019-12-06)Individuals in industrialized countries spend a substantial part of life in the non-fasting, postprandial state, which is also associated with increased oxidation and inflammation. Furthermore, a high body mass index (BMI) is the third cause of mortality in the world. In this PhD thesis, obese (BMI>30) individuals with and without metabolic disease (n=50) was included, in addition to a normal ... -
Early Markers of Metabolic Dysregulation in Obese Individuals - Identification at Baseline and Effect of Modest Weight Loss
(Doctoral thesis; Doktorgradsavhandling, 2023-11-15)<p><i>Background:</i> Evidence suggests that the link between obesity and chronic lifestyle disease is chronic, low-grade inflammation. Leptin and adiponectin play principal roles in inducing inflammation and promoting insulin resistance, resulting in metabolic syndrome. Our study aimed to find clinically feasible biologic markers to identify metabolically dysregulated obese individuals and to study ... -
Early menarche and other endocrine disrupting effects of per- and polyfluoroalkyl substances (PFAS) in adolescents from Northern Norway. The Fit Futures study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-19)Background: Per- and polyfluoroalkyl substances (PFAS) comprise a large group of chemicals that are ubiquitous in the environment and include recognized persistent organic pollutants. The aim of this cross-sectional study was to investigate possible endocrine disrupting effects of different PFAS in adolescents. <p> <p>Methods: Serum concentrations of PFAS, thyroid, parathyroid and steroid hormones ... -
Early performance measures following regular versus irregular screening attendance in the population-based screening program for breast cancer in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-11)Irregular attendance in breast cancer screening has been associated with higher breast cancer mortality compared to regular attendance. Early performance measures of a screening program following regular versus irregular screening attendance have been less studied. We aimed to investigate early performance measures following regular versus irregular screening attendance. Methods We used information ... -
Early pregnancy body mass index and spontaneous preterm birth in Northwest Russia: a registry-based study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-09-04) -
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-07)Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy in a cohort of 32 acute myeloid leukemia (AML) patients, using 36-dimensional mass cytometry. Through supervised and unsupervised machine learning approaches, we find that reduction of ... -
Early screening outcomes among non-immigrants and immigrants targeted by BreastScreen Norway, 2010–2019
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-31)Aims: This study aimed to analyse results on early screening outcomes, including recall and cancer rates, and histopathological tumour characteristics among non-immigrants and immigrants invited to BreastScreen Norway. Methods: We included information about 2, 763,230 invitations and 2,087,222 screening examinations from 805,543 women aged 50–69 years who were invited to BreastScreen Norway between ... -
Early screening outcomes before, during, and after a randomized controlled trial with digital breast tomosynthesis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-01)Purpose: To describe and compare early screening outcomes before, during and after a randomized controlled trial with digital breast tomosynthesis (DBT) including synthetic 2D mammography versus standard digital mammography (DM) (To-Be 1) and a follow-up cohort study using DBT (To-Be 2). <p><p>Methods: Retrospective results of 125,020 screening examinations from four consecutive screening rounds ... -
Early self-reported pain in juvenile idiopathic arthritis (JIA) is related to long-term outcomes. Results from the Nordic JIA cohort study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-28)<p><i>Objective</i>: To study self‐reported pain early in the disease course of juvenile idiopathic arthritis (JIA) as predictor of long‐term disease outcomes.</p> <p><i>Methods</i>: Consecutive cases of JIA with disease onset 1997‐2000 from defined geographical areas of Norway, Sweden, Finland and Denmark were prospectively enrolled in this population‐based cohort study. Self‐reported, disease‐related ... -
Early sexual behaviour and Chlamydia trachomatis infection - a population based cross-sectional study on gender differences among adolescents in Norway.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)Early sexual behaviour has been shown to differ significantly between genders, but few studies have addressed this topic to explain the commonly observed differences in chlamydia rates between adolescent girls and boys. Our study aimed to determine chlamydia prevalence in adolescents aged 15–20 years in a high-incidence area in Norway, and to identify gender-specific early sexual behaviours associated ...