Background: Over the last two decades, the number of studies on electronic symptom reporting has increased greatly. However, the field is very heterogeneous: the choices of patient groups, health service innovations, and research targets seem to involve a broad range of foci. To move the field forward, it is necessary to build on work that has been done and direct further research to the areas holding ...

Avhandlingen fokuserer på elektronisk tilgjengelige symptom data, nytte og gjennomførbarhet mht sykdomsovervåking og helsetjeneste forbedringer. To hovedspørsmål er adressert: 1. Er et nytt system for overvåkning av smittsomme sykdommer nødvendig, og i så tilfelle, hva er den mest pålitelige og egnede datakilden? Både data hentet fra EPJ-systemer, og pre-konsultasjon symptom-data rapportert av ...

Wound healing is a complex and highly regulated process, vital for preserving the barrier function of the skin. However, several underlying pathologies have the ability to influence the cascade of events involved in this process, resulting in the development of chronic wounds. The heterogeneous nature of chronic wounds increases the requirements of novel wound dressings. Hence, the development of ...

The physical stability is crucial in formulating liposomes for drug delivery applications. The objective of the present study was to develop and evaluate the electrospun amphiphilic nanofibers intended for the templates and delivery of drug-loaded liposomes. This approach exploits the hydration of phospholipids deposited on electrospun nanofibers for the formation of liposomes, and the strategy was ...

Formål: 1) Vurdere den umiddelbare effekten av elektrokonvertering i behandlingen av persisterende atrieflimmer og om mulig identifisere faktorer som predikerer suksess. 2) Vurdere den langvarige effekten av elektrokonvertering og om mulig identifisere faktorer som predikerer residiv og kronifisering. Hvilke komplikasjoner til arytmien tilkommer i løpet av en femårsperiode? 3) Vurdere om pasienter ...

Sammendrag Samhandlingsreformen er å anse som oppstarten for elektronisk kommunikasjon i helse- og omsorgssektoren. Denne dialogformen skulle bidra til raskere og sikrere informasjonsutveksling og sømløse pasientforløp. Forskning viser likevel utfordringsområder som bidrar til samhandlingsvansker de ulike tjenestenivåene imellom. Oppgavens problemstilling: «Hvordan skaper elektroniske meldinger ...

Although hypertension is a risk factor for end-stage renal disease, this complication develops in only a minority of hypertensive patients. Whether non-malignant hypertension itself is sufficient to cause reduced glomerular filtration rate (GFR) is unclear. We investigated whether elevated blood pressure (BP) was associated with accelerated GFR decline in the general population. The study ...

Background Questions remain concerning to what extent age and sex may modify the suggested association between psoriasis and the metabolic syndrome in the general population. Objectives To investigate the association between psoriasis and the metabolic syndrome within a large population-based cohort by age and sex.<p> <p>Methods A cross-sectional study including 10 521 participants aged 30–79 ...

Venous thromboembolism (VTE) is a common, multi-causal disease with potentially serious short- and long-term complications. In clinical practice, there is a need for improved plasma biomarker-based tools for VTE diagnosis and risk prediction. Here we show, using proteomics profiling to screen plasma from patients with suspected acute VTE, and several case-control studies for VTE, how Complement ...

<p><i>Background</i> D-dimer, a global biomarker for activation of the coagulation and fibrinolysis systems, is useful in assessing individual risk of venous thromboembolism (VTE) recurrence. However, there is limited information on the association between D-dimer and risk of a first lifetime VTE event. <p><i>Objectives</i> To investigate the association between plasma D-dimer levels and risk of ...