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    • A randomized controlled pilot study assessing feasibility and safety of a wilderness program for childhood, adolescent, and young adult cancer survivors: the WAYA study 

      Jong, Maria Catharina; Dahlqvist, Heléne; Lown, E. Anne; Schats, Winnie; Beckman, Lars; Jong, Mats (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-08)
      Background The majority of childhood, Adolescent and Young Adult (AYA) cancer survivors suffers from long-lasting health issues following cancer treatment. It is therefore critical to explore effective health promotion strategies to address their needs. Exposure to nature is a promising approach to support the needs of young cancer survivors. This study investigated whether it is feasible to ...

    • A randomized controlled trial comparing self-referral to inpatient treatment and treatment as usual in patients with severe mental disorders 

      Sigrunarson, Vidir; Moljord, Inger Elise Opheim; Steinsbekk, Aslak; Eriksen, Lasse; Morken, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      <b>Background:</b> There has been a call for increased patient autonomy and participation in psychiatry. Some Community Mental Health Centers (CMHC) have implemented services called “self-referral to inpatient treatment” (SRIT) for patients with severe mental disorders.<br> <b>Aims:</b> To investigate whether SRIT could yield better outcomes after 12 months in use of mental health services ...

    • A randomized controlled trial of a six-session cognitive behavioral treatment of emotional disorders in adolescents 14–17 years old in child and adolescent mental health services (CAMHS) 

      Lorentzen, Veronica; Fagermo, Kenneth; Handegård, Bjørn Helge; Skre, Ingunn; Neumer, Simon-Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-14)
      <i>Background</i> - This study aims to investigate effectiveness of a 6-week, transdiagnostic cognitive behavioral therapy (CBT) for anxiety and depression in adolescents, the Structured Material for Therapy (SMART), in naturalistic settings of child and adolescent mental health outpatient services (CAMHS).<p><p> <i>Methods</i> - A randomized controlled trial with waiting list control (WLC) was ...

    • A randomized controlled trial on a smartphone self-help application (Be Good to Yourself) to reduce depressive symptoms 

      Lüdtke, Thies; Pult, Lilian Klara; Schröder, Johanna; Moritz, Steffen; Bücker, Lara (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-29)
      Depressive symptoms are common, yet only a subgroup of individuals receive adequate treatment. To reduce the treatment gap, several online self-help programs have been developed, yielding small to moderate effects. We developed a smartphone self-help application addressing depressive symptoms. We sought to evaluate its feasibility and efficacy in participants reporting a subjective need for help (a ...

    • Randomized phase II trial comparing twice daily hyperfractionated with once daily hypofractionated thoracic radiotherapy in limited disease small cell lung cancer 

      Grønberg, Bjørn Henning; Halvorsen, Tarje Onsøien; Fløtten, Øystein; Brustugun, Odd Terje; Brunsvig, Paal Fr.; Aasebø, Ulf; Bremnes, Roy M.; Tollåli, Terje; Hornslien, Kjersti; Aksnessæther, Bjørg Y.; Liaaen, Erik Dyb; Sundstrøm, Stein Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-23)
      <br>BACKGROUND: <br> Concurrent chemotherapy and thoracic radiotherapy (TRT) is recommended for limited disease small cell lung cancer (LD SCLC). Twice daily TRT is well documented, but not universally implemented - probably mainly due to inconvenience and concerns about toxicity. A schedule of three-week hypofractionated TRT is a commonly used alternative. This is the first randomized trial ...

    • Randomized trial of a novel game-based appointment system for a university hospital venereology unit: Study protocol 

      Gabarron, Elia; Fernandez-Luque, Luis; Serrano, Artur; Wynn, Rolf; Schopf, Thomas Roger Griesbeck (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-08)
      Background: Chlamydia is the most common reportable sexually transmitted disease (STD) in Norway, and its incidence in the two northernmost counties has been disclosed to be nearly the double of the Norwegian average. The latest publicly available rates showed that 85.6% of the new cases were diagnosed in people under 29 years old. The information and communication technologies are among the most ...

    • Randomized trial of a novel game-based appointment system for a university hospital venereology unit: Study protocol 

      Gabarron, Elia; Serrano, Artur; Fernandez Luque, Luis; Wynn, Rolf; Schopf, Thomas Roger Griesbeck (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-08)
      <p>Background: Chlamydia is the most common reportable sexually transmitted disease (STD) in Norway, and its incidence in the two northernmost counties has been disclosed to be nearly the double of the Norwegian average. The latest publicly available rates showed that 85.6% of the new cases were diagnosed in people under 29 years old. The information and communication technologies are among the ...

    • Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction 

      Broch, Kaspar; Anstensrud, Anne Kristine; Woxholt, Sindre; Sharma, Kapil Kishore; Tøllefsen, Ingvild Maria; Bendz, Bjørn; Aakhus, Svend; Ueland, Thor; Amundsen, Brage H.; Damås, Jan Kristian; Berg, Erlend; Bjørkelund, Elisabeth; Bendz, Christina; Hopp, Einar; Kleveland, Ola; Stensæth, Knut Haakon; Opdahl, Anders; Kløw, Nils-Einar; Seljeflot, Ingebjørg; Andersen, Geir Øystein; Wiseth, Rune; Aukrust, Pål; Gullestad, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-12)
      <p><i>Background - </i>Prompt myocardial revascularization with percutaneous coronary intervention (PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation myocardial infarction (STEMI). However, as much as 50% of the loss of viable myocardium may be attributed to the reperfusion injury and the associated inflammatory response. <p><i>Objectives - </i>This study sought ...

    • A randomized trial of telemedicine efficacy and safety for nonacute headaches 

      Müller, Kai Ivar; Alstadhaug, Karl Bjørnar; Bekkelund, Svein Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-11)
      <p><i>Objective</i>: To evaluate long-term treatment efficacy and safety of one-time telemedicine consultations for nonacute headaches.</p> <p><i>Methods</i>: We randomized, allocated, and consulted nonacute headache patients via telemedicine (n = 200) or in a traditional manner (n = 202) in a noninferiority trial. Efficacy endpoints, assessed by questionnaires at 3 and 12 months, included change ...

    • Rapid changes in sociosexual behaviors around transition to and from behavioral estrus, in female rats housed in a seminatural environment 

      Le Moene, Olivia; Hernandez-Arteaga, Enrique; Chu, Xi; Ågmo, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-28)
      Gonadally intact female rats display sexual behaviors only during a portion of the estrus cycle. In standard experimental setups, the on- and offset of sexual behavior is gradual. However, in naturalistic settings, it is almost instantaneous. We assessed the changes in sociosexual behaviors at the beginning and end of behavioral estrus in ovariectomized females treated with ovarian hormones. Rats ...

    • A rapid chemokine response of macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and the regulated on activation, normal T expressed and secreted chemokine is associated with a sustained virological response in the treatment of chronic hepatitis C 

      Florholmen, Jon; Kristiansen, Magnhild Gangsøy; Steigen, sonja eriksson; Sørbye, Sveinung Wergeland; Paulssen, Eyvind Jakob; Kvamme, J.M.; Zbigniew, Konopski; Gutteberg, tore jarl; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The role of chemokines in chronic hepatitis C virus (HCV) infection is not fully understood. The present study aimed to characterize the baseline serum concentrations and the initial β-chemokine response to treatment with interferon-α and ribavirin with respect to the final clinical outcome of virological response to treatment. Serum concentrations of alanine aminotransferase (ALT) and of the CC ...

    • Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022 

      Linkevicius, Marius; Bonnin, Rémy A; Alm, Erik; Svartström, Olov; Apfalter, Petra; Hartl, Rainer; Hasman, Henrik; Roer, Louise; Räisänen, Kati; Dortet, Laurent; Pfennigwerth, Niels; Hans, Jörg B; Tóth, Ákos; Buzgó, Lilla; Cormican, Martin; Delappe, Niall; Monaco, Monica; Giufrè, Maria; Hendrickx, Antoni Pa; Samuelsen, Ørjan; Pöntinen, Anna Kaarina; Caniça, Manuela; Manageiro, Vera; Oteo-Iglesias, Jesús; Pérez-Vázquez, María; Westmo, Karin; Mäkitalo, Barbro; Palm, Daniel; Monnet, Dominique L.; Kohlenberg, Anke (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-11)
      Whole genome sequencing data of 874 Escherichia coli isolates carrying blaNDM-5 from 13 European Union/ European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were ...

    • Rapid extrication of entrapped victims in motor vehicle wreckage using a Norwegian chain method - cross-sectional and feasibility study 

      Fattah, Sabina; Johnsen, Anne Siri; Andersen, Jan Einar; Vigerust, Trond; Olsen, Terje; Rehn, Marius (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencing 

      Taxt, Arne Michael; Avershina, Ekaterina; Frye, Stephan Alfons; Naseer, Mohammed Umaer; Ahmad, Rafi (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-06)
      Bloodstream infections (BSI) and sepsis are major causes of morbidity and mortality worldwide. Blood culture-based diagnostics usually requires 1–2 days for identification of bacterial agent and an additional 2–3 days for phenotypic determination of antibiotic susceptibility pattern. With the escalating burden of antimicrobial resistance (AMR) rapid diagnostics becomes increasingly important to ...

    • A rapid, sensitive, and specific assay to measure TF activity based on chromogenic determination of thrombin generation 

      Østerud, Bjarne; Latysheva, Nadezhda; Schoergenhofer, Christian; Jilma, Bernd; Hansen, John-Bjarne; Snir, Omri (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)
      Background - Most tissue factor (TF) activity assays are based on measurement of factor X (FX) activation by TF in the presence of factor VII (FVII)/FVIIa. This requires long incubation, which may result in TF-independent activity of FX and inaccurate measurement of TF activity.<p> <p>Aim - To develop a sensitive and specific TF activity assay, which does not register a non-specific TF activity, ...

    • Rapport - Workshop om fremtidens skredopplæring 

      Dassler, Tim; Skille, Tarjei Tveito; Pfuhl, Gerit; Fjellaksel, Richard (Research report; Forskningsrapport, 2023)
      2. november 2023 gjennomførte Norskred i samarbeid med Nortind, Den norske turistforeningen (DNT), Norsk fjellsportforum (NF) og UiT CARE – senter for snøskredforskning en workshop om fremtidens skredopplæring i Norge. Workshopen ble arrangert dagen før den nordiske skredkonferansen 2023 på Oppdal.<p> <p>Dagens modell for skredopplæring inneholder mange læringsmål og en kursstige som virker å ...

    • Rapport fra 25. juni-utvalget: Evaluering av PST og politiet 

      Jansen, Pia Therese; Ravndal, Jacob Aasland; Skoglund, Gisle; Eriksen, Christoffer Conrad; Hoven, Siren; Løberg, Anders; Rolfheim-Bye, Christina Lill (Research report; Forskningsrapport, 2023)

    • Rapport fra SAK-prosjektet "Legemiddelhåndtering og medikamentregning - Nettstøttet emne i sykepleierutdanningen" 

      Olsen, Kari Birkelund; Perander, Bente; Barstad, Maud Ann-Sophie (Research report; Forskningsrapport, 2016-09-20)
      Det ble innledet SAK-samarbeid mellom sykepleierutdanningene i Tromsø, Harstad og Hammerfest. Målet med dette samarbeidet var å styrke utdanningen av sykepleiere spesielt til kommunehelsetjenesten i landsdelen. Alle tre institusjoner hadde etablert deltidsstudier eller desentraliserte deltidsstudier med innslag av nettstøttet undervisning. Ønske om å styrke samarbeidet innenfor sykepleierutdanning ...

    • Rapport fra seksualvaneundersøkelsene i 1987, 1992, 1997 og 2002 

      Træen, Bente; Stigum, Hein; Magnus, Per (Research report; Forskningsrapport, 2003)
      Bakgrunn Kunnskap om befolkningens seksualvaner er nødvendig for å forstå, forutsi og forebygge spredning av seksuelt overførbare sykdommer slik som HIV/AIDS, klamydia, humant papilloma virus og herpes. Videre er slik kunnskap viktig for å forebygge uønskede svangerskap. På denne bakgrunn har Nasjonalt folkehelseinstitutt (fram til 2002 Folkehelsa) med 5 års mellomrom gjennomført undersøkelser for ...

    • Rapport omsvangerskapsavbrot 2022 

      Akerkar, Rupali Rajendra; Askeland, Olaug Margrete; Halvorsen, Guri Sundgot; Heiberg-Andersen, Rannveig; Hornæs, Mona Tornensis; Juliusson, Pétur Benedikt; Berg, Amund (Research report; Forskningsrapport, 2023)
      Det føreligg statistikk over talet på begjæringar, tal på innvilga begjæringar i nemnd og tal på utførte svangerskapsavbrot i Noreg sidan 1979. Statistisk sentralbyrå hadde ansvaret for abortstatistikken frå 1979 til og med 2005. Frå og med 2006 har Folkehelseinstituttet vore ansvarleg for statistikken, og frå og med 2008 ansvarleg for databehandlinga av Register over svangerskapsavbrudd (Abo ...