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    • Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene 

      Emblem, Åse; Knutsen, Erik; Jørgensen, Tor Erik; Fure, Hilde; Johansen, Steinar Daae; Brekke, Ole Lars; Mollnes, Tom Eirik; Karlsen, Bård Ove (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-29)
      Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat invading microorganisms. Understanding the expression of long non-coding RNAs containing Alu elements in inflammation is important for reconstructing ...

    • Blood Volume, Hemoglobin Mass, and Peak Oxygen Uptake in Older Adults: The Generation 100 Study 

      Lundgren, Kari Margrethe; Aspvik, Nils Petter; Langlo, Knut Asbjørn Rise; Braaten, Tonje Bjørndal; Wisløff, Ulrik; Stensvold, Dorthe; Karlsen, Trine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-01)
      <p>Purpose: To investigate the association between blood volume, hemoglobin mass (Hb<sub>mass</sub>), and peak oxygen uptake (VO<sub>2peak</sub>) in healthy older adults. <p>Methods: Fifty fit or unfit participants from the prospective randomized Generation 100 Study (<i>n</i> = 1,566) were included (age- and sex-specific VO<sub>2peak</sub> above or below average values). Blood, plasma, and erythrocyte ...

    • Bo og leve i eget hjem, eller innlagt på institusjon. Hvordan sykepleiere i hjemmebasert omsorg vurderer grunnlaget for overflytting fra eget hjem til institusjon for den gamle pasient. 

      Horn, Per Eivind (Master thesis; Mastergradsoppgave, 2018-05-05)
      Studien fant at det er fire hovedtemaer som kan bidra til å belyse sykepleiernes vurderinger av innleggelse til sykehjem, 1) Helsesvikt hos pasienten, 2) Hjemmesituasjonen til pasienten, 3) Ressurser rundt pasienten og 4) Autonomi, inkludert egenomsorg og maktforståelse. Studien er en kvalitativ undersøkelse basert på semistrukturerte intervju med fire sykepleiere med lang erfaring i ulike hjemmebaserte ...

    • Bodily cleanliness in modern nursing 

      Boge, Jeanne Helene; Kristoffersen, Kjell; Martinsen, Kari Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-03-11)
      Why are bodily washing practices the way they are in nursing? Michel Foucault argues that modern democratic societies discipline human bodies in accordance with political interests. In the extension of that argumentation we will show that bodily cleanliness in modern nursing may have been used as a disciplining tool. The first part of our discussion takes as its point of departure the second half ...

    • Body composition and physical fitness in women with bulimia nervosa or binge-eating disorder. 

      Mathisen, Therese Fostervold; Rosenvinge, Jan H; Friborg, Oddgeir; Pettersen, Gunn; Stensrud, Trine; Hansen, Bjørge Hermann; Underhaug, Karoline; Teinung, Elisabeth; Vrabel, KariAnne; Svendsen, Mette; Bratland-Sanda, Solfrid; Sundgot-Borgen, Jorunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-23)
      <p><i>Objective</i>: Knowledge about physical fitness in women with bulimia nervosa (BN) or binge‐eating disorder (BED) is sparse. Previous studies have measured physical activity largely through self‐report, and physical fitness variables are mainly restricted to body mass index (BMI) and bone mineral density. We expanded the current knowledge in these groups by including a wider range of physical ...

    • Body composition, parathyroid hormone and vitamin D : results from the Tromsø Study and from an intervention study with high doses of cholecalciferol 

      Sneve, Monica (Doctoral thesis; Doktorgradsavhandling, 2009-06-18)
      I den epidemiologiske delen har vi brukt data fra den fjerde og den femte Tromsø undersøkelsen. Vi fant at kroppsmasseindeks (KMI) var nært knyttet til røykestatus og at personer som røkte 5–10 sigaretter per dag hadde lavest KMI. Vi fant også at personer med høyt nivå av parathyroideahormon (PTH, er sentralt hormon i kalkstoffskiftet) hadde lavere beintetthet og større fettmasse enn personer med ...

    • Body mass index and cognitive function in community-living elderly men and women: The Tromsø Study 

      Ylvisaker, Ida J.E. (Master thesis; Mastergradsoppgave, 2020-04-01)
      <p><i>Background:</i> Previous studies have reported conflicting results regarding the relationship between cognitive function and nutritional status in the elderly. The primary objective of this study was to investigate the associations between body mass index (BMI) and cognitive function in a sample of community-living elderly men and women. <p><i>Methods:</i> This population-based study comprised ...

    • Body mass index and mortality in elderly men and women: the Tromso and HUNT studies 

      Kvamme, Jan-Magnus; Holmen, Jostein; Wilsgaard, Tom; Florholmen, Jon; Midthjell, Kristian; Jacobsen, Bjarne Koster (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The impact of body mass index (BMI; kg/m2) and waist circumference (WC) on mortality in elderly individuals is controversial and previous research has largely focused on obesity. With special attention to the lower BMI categories, associations between BMI and both total and cause-specific mortality were explored in 7604 men and 9107 women aged ≥65 years who participated in the Tromsø Study (1994–1995) ...

    • Body mass index and risk of malnutrition in community-living elderly men and women: relationships with morbidity, mortality and health- related quality of life. The Tromsø and HUNT studies 

      Kvamme, Jan-Magnus (Doctoral thesis; Doktorgradsavhandling, 2011-06-09)
      The elderly population is rapidly growing, and elderly individuals are more vulnerable to nutritional problems than other adults. A number of studies have found evidence for adverse health outcomes in elderly patients at risk of malnutrition. However, much of the previous research has been performed in hospital populations or in groups of elderly patients with specific diagnoses. More population-based ...

    • Body mass index and survival in women with breast cancer—systematic literature review and meta-analysis of 82 follow-up studies 

      Chan, Doris S.M.; Vieira, A.; Aune, Dagfinn; Bandera, Elisa V.; Greenwood, D; McTiernan, A; Rosenblatt, D. Navarro; Thune, Inger; Vieira, R; Norat, T (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-04-27)
      Background: Positive association between obesity and survival after breast cancer was demonstrated in previous meta-analyses of published data, but only the results for the comparison of obese versus non-obese was summarised.<p> <p>Methods: We systematically searched in MEDLINE and EMBASE for follow-up studies of breast cancer survivors with body mass index (BMI) before and after diagnosis, and ...

    • Body mass index at age 20 and subsequent childbearing: The Adventist Health Study-2. 

      Jacobsen, Bjarne Koster; Knutsen, Synnøve Fønnebø; Oda, Keiji; Fraser, Gary E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Some epidemiological, clinical, and laboratory studies suggest that underweight and obesity impact fertility. Methods: This is cross-sectional study of 33,159 North American Adventist women, who were nulliparous at age 20 years and who, as a group, have a healthy lifestyle. Logistic regression analysis was used to assess how body mass index (BMI, kg/m2) at age 20 was related to never ...

    • Body mass index i ungdomsårene og risiko for død. En prospektiv kohortstudie bestående av 238 839 unge norske menn 

      Danielsen, Eirin Marlene Karlsen (Master thesis; Mastergradsoppgave, 2017-09-10)
      Bakgrunn: Prevalensen av overvekt og fedme har økt globalt i en slik grad at det snakkes om at vi står ovenfor global fedmeepidemi. Forskningslitteratur har vist at overvekt og fedme i ungdomstiden øker risikoen morbiditet og mortalitet. Formål: Jeg ønsker å undersøke sammenhengen mellom BMI i ungdomsalder og mortalitet i en nasjonal populasjon bestående av menn. Materiale og metode: Datamaterialet ...

    • Body mass index, waist circumference and pre-frailty/frailty: the Tromsø study 1994−2016 

      Uchai, Shreeshti; Andersen, Lene Frost; Hopstock, Laila Arnesdatter; Hjartåker, Anette (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-23)
      Objective This study investigated the association between obesity, assessed using body mass index (BMI) and waist circumference (WC), and pre-frailty/frailty among older adults over 21 years of follow-up. <p>Design Prospective cohort study. <p>Setting Population-based study among communitydwelling adults in Tromsø municipality, Norway. <p>Participants 2340women and 2169 men aged ≥45 years ...

    • Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study 

      Sedlmeier, Anja M.; Viallon, Vivian; Ferrari, Pietro; Peruchet-Noray, Laia; Fontvieille, Emma; Amadou, Amina; Seyed Khoei, Nazlisadat; Weber, Andrea; Baurecht, Hansjörg; Heath, Alicia K.; Tsilidis, Kostas; Kaaks, Rudolf; Katzke, Verena; Inan-Eroglu, Elif; Schulze, Matthias B.; Overvad, Kim; Bonet, Catalina; Ubago-Guisado, Esther; Chirlaque, María-Dolores; Ardanaz, Eva; Perez-Cornago, Aurora; Pala, Valeria; Tumino, Rosario; Sacerdote, Carlotta; Pasanisi, Fabrizio; Borch, Kristin Benjaminsen; Rylander, Charlotta; Weiderpass, Elisabete; Gunter, Marc J.; Fervers, Béatrice; Leitzmann, Michael F.; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-02)
      Background - Classical anthropometric traits may fail to fully represent the relationship of weight, adiposity, and height with cancer risk. We investigated the associations of body shape phenotypes with the risk of overall and site-specific cancers.<p> <p>Methods - We derived four distinct body shape phenotypes from principal component (PC) analysis on height, weight, body mass index (BMI), waist ...

    • Body Size at Different Ages and Risk of 6 Cancers: A Mendelian Randomization and Prospective Cohort Study 

      Mariosa, Daniela; Smith-Byrne, Karl; Richardson, Tom G.; Ferrari, Pietro; Gunter, Marc J.; Papadimitriou, Nikos; Murphy, Neil; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Riboli, Elio; Muller, David; Purdue, Mark P.; Chanock, Stephen J.; Hung, Rayjean J.; Amos, Christopher I.; O'Mara, Tracy A.; Amiano, Pilar; Pasanisi, Fabrizio; Rodriguez-Barranco, Miguel; Krogh, Vittorio; Tjønneland, Anne; Halkjær, Jytte; Perez-Cornago, Aurora; Chirlaque, María-Dolores; Skeie, Guri; Rylander, Charlotta; Borch, Kristin Benjaminsen; Aune, Dagfinn; Heath, Alicia K.; Ward, Heather A.; Schulze, Matthias; Bonet, Catalina; Weiderpass, Elisabete; Davey Smith, George; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-19)
      It is unclear if body weight in early life affects cancer risk independently of adult body weight. To investigate this question for 6 obesity-related cancers, we performed univariable and multivariable analyses using 1) Mendelian randomization (MR) analysis and 2) longitudinal analyses in prospective cohorts. Both the MR and longitudinal analyses indicated that larger early life body size was ...

    • Body size indicators and risk of gallbladder cancer: Pooled analysis of individual-level data from 19 prospective cohort studies 

      Campbell, Peter T.; Newton, Christina C.; Kitahara, Cari M.; Patel, Alpa V.; Hartge, Patricia; Koshiol, Jill; McGlynn, Katherine A.; Adami, Hans Olov; de González, Amy Berrington; Freeman, Laura E. Beane; Bernstein, Leslie; Buring, Julie E.; Freedman, Neal D.; Gao, Yu-Tang; Giles, Graham G.; Gunter, Mark J.; Jenab, Mazda; Liao, Linda M.; Milne, Roger L.; Robien, Kim; Sandler, Dale P.; Schairer, Catherine; Sesso, Howard D.; Shu, Xiao-Ou; Weiderpass, Elisabete; Wolk, Alicja; Xiang, Yong-Bing; Zeleniuch-Jacquotte, Anne; Zheng, Wei; Gapstur, Susan M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-17)
      Background: There are few established risk factors for gallbladder cancer beyond gallstones. Recent studies suggest a higher risk with high body mass index (BMI), an indicator of general heaviness, but evidence from other body size measures is lacking. <br> Methods: Associations of adult BMI, young adult BMI, height, adult weight gain, waist circumference (WC), waist–height ratio (WHtR), hip ...

    • Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures 

      Nilsen, Ole Andreas; Ahmed, Luai A.; Winther, Anne; Christoffersen, Tore; Thrane, Gyrd; Evensen, Elin; Furberg, Anne-Sofie; Grimnes, Guri; Dennison, Elaine; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-04)
      Determinants of bone acquisition in late adolescence and early adulthood are not well‐described. This 2‐year follow‐up study explored the associations of body weight (BW), body mass index (BMI), and changes in weight status with adolescent bone accretion in a sample of 651 adolescents (355 girls and 296 boys) between 15 and 19 years of age from The Tromsø Study: Fit Futures. This Norwegian ...

    • Body, participation and self transformations during and after in-patient stroke rehabilitation 

      Arntzen, Cathrine; Hamran, Torunn; Borg, Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-04)
      This study explores stroke survivors’ experience of being part of an institutional rehabilitation context and what it means for the immediate experience of discharge home. The aim is to develop a deeper understanding of how the dynamic phenomenon body, participation in everyday life and sense of self interrelates and changes through stroke survivors’ movement in and between the two contexts and ...

    • Body-mass indeks hos menn i alderen 17-19 år og risiko for død av ischemisk hjertesykdom. En prospektiv kohortstudie bestående av 43 024 norske menn. 

      Braseth, Synne Marie Roghell (Master thesis; Mastergradsoppgave, 2019-06-02)
      Bakgrunn: På verdensbasis har man over flere tiår sett en økning i prevalensen av overvekt og fedme, og spesielt blant den yngre delen av befolkningen. Det har blitt publisert store mengder fagartikler som viser at overvekt og fedme øker risiko for morbiditet og mortalitet, av en rekke årsaker. Hjerte- og karsykdom er sterkt assosiert med fedme, og i flere studier framkommer det også at BMI i barndom ...

    • Bone Marrow Adipocytes: The Enigmatic Components of the Hematopoietic Stem Cell Niche 

      Cuminetti, Vincent; Arranz, Lorena (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-18)
      Bone marrow adipocytes (BMA) exert pleiotropic roles beyond mere lipid storage and filling of bone marrow (BM) empty spaces, and we are only now beginning to understand their regulatory traits and versatility. BMA arise from the differentiation of BM mesenchymal stromal cells, but they seem to be a heterogeneous population with distinct metabolisms, lipid compositions, secretory properties and ...