Blar i forfatter Det helsevitenskapelige fakultet "Flo, Kari"
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Effect of Passive Leg Raising on Systemic Hemodynamics of Pregnant Women: A Dynamic Assessment of Maternal Cardiovascular Function at 22–24 Weeks of Gestation
Vårtun, Åse; Flo, Kari; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Longitudinal reference ranges for maternal plasma laeverin, and its role as a potential biomarker of preeclampsia
Nystad, Mona; Sitras, Vasilis; Flo, Kari; Widnes, Christian; Vårtun, Åse; Wilsgaard, Tom; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-25)Background: Laeverin is a placenta-specific membrane-bound aminopeptidase. In this study we wanted to: 1) serially measure plasma levels of laeverin in healthy women during the second half of pregnancy and postpartum, 2) determine whether laeverin is differently expressed at 22–24 weeks in women who later develop preeclampsia compared to controls, 3) compare laeverin protein expression in placenta ... -
Maternal cardiac function, uterine artery hemodynamics and natriuretic peptides at 22-24 weeks of gestation and subsequent development of hypertensive disorders of pregnancy
Liang, Huan; Vårtun, Åse; Flo, Kari; Widnes, Christian; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-26)<p><i>Introduction - </i>Maternal cardiac dysfunction as well as abnormal uterine artery (UtA) Doppler are associated with hypertensive disorders of pregnancy (HDP), but their relation is unclear. We investigated the correlation between maternal cardiac function, UtA hemodynamics and natriuretic peptides, and explored differences between women who subsequently developed HDP and those who did ... -
Maternal functional hemodynamics in the second half of pregnancy: A longitudinal study
Vårtun, Åse; Flo, Kari; Wilsgaard, Tom; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-10)Objective: Cardiovascular response to passive leg raising (PLR) is useful in assessing preload reserve, but it has not been studied longitudinally during pregnancy. We aimed to investigate gestational age associated serial changes in maternal functional hemodynamics and establish longitudinal reference ranges for the second half of pregnancy. Materials and Methods: This was a prospective ... -
Sex differences in umbilical artery Doppler indices: A longitudinal study
Widnes, Christian; Flo, Kari; Wilsgaard, Tom; Kiserud, Torvid; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-18)<p><i>Background</i>: Sexual dimorphism in placental size and function has been described. Whether this influences the clinically important umbilical artery (UA) waveform remains controversial, although a few cross-sectional studies have shown sex differences in UA pulsatility index (PI). Therefore, we tested whether fetal sex influences the UA Doppler indices during the entire second half of pregnancy ... -
Static and functional hemodynamic profiles of women with abnormal uterine artery doppler at 22-24 weeks of gestation
Vårtun, Åse; Flo, Kari; Widnes, Christian; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)Objective To compare cardiac function, systemic hemodynamics and preload reserve of women with increased (cases) and normal (controls) uterine artery (UtA) pulsatility index (PI) at 22–24 weeks of gestation. Materials and Methods A prospective cross-sectional study of 620 pregnant women. UtA blood flow velocities were measured using Doppler ultrasonography, and PI was calculated. Mean UtA ...