• Achievements of primary prevention targets in individuals with high risk of cardiovascular disease: an 8-year follow-up of the Tromsø study 

      Hagen, Amalie Nilsen; Ariansen, Inger Kristine Holtermann; Hanssen, Tove Aminda; Lappegård, Knut Tore; Eggen, Anne Elise; Løchen, Maja-Lisa; Njølstad, Inger; Wilsgaard, Tom; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-22)
      Aims To study change over 8 years in cardiovascular risk, achievement of national guideline-based treatment targets of lipids, blood pressure (BP) and smoking in primary prevention of cardiovascular disease (CVD), medication use, and characteristics associated with target achievement among individuals with high CVD risk in a general population.<p> <p>Methods and results We followed 2524 women ...
    • Adherence to lifestyle recommendations among Norwegian cancer survivors and the impact of traditional and complementary medicine use: the Tromsø Study 2015–2016 

      Nakandi, Kiwumulo; Benebo, Faith Owunari; Hopstock, Laila Arnesdatter; Stub, Trine; Kristoffersen, Agnete Egilsdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-19)
      Introduction Adherence to healthy lifestyle recommendations has positive effects on cancer outcomes yet adherence is low among cancer survivors. Differences in adherence between women and men, phase of survivorship, and other factors that might increase adherence, like the use of traditional and complementary medicine (T&CM), need to be explored. We aimed to study the adherence to national recommendations ...
    • Anthropometric measures are satisfactory substitutes for the DXA‐derived visceral adipose tissue in the association with cardiometabolic risk—The Tromsø Study 2015–2016 

      Lundblad, Marie Wasmuth; Jacobsen, Bjarne Koster; Johansson, Jonas; Grimsgaard, Sameline; Andersen, Lene Frost; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-03)
      Background - Body mass index (BMI) increases while cardiometabolic risk factors decrease in individuals in high-income countries. This paradoxical observation raises the question of whether current measures of overweight and obesity properly identify cardiometabolic risk.<p> <p>Methods - A total of 3675 participants (59% women) aged 40–84 years with whole-body dual-energy x-ray absorptiometry ...
    • The association between anemia and falls in community-living women and men aged 65 years and older from the fifth Tromsø Study 2001-02: a replication study 

      Hopstock, Laila Arnesdatter; Utne, Elisabeth Bøe; Horsch, Alexander; Skjelbakken, Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-27)
      Background: <br> Falls are common among elderly people, and the risk increase with age. Falls are associated with both health and social consequences for the patient, and major societal costs. Identification of risk factors should be investigated to prevent falls. Previous studies have shown anemia to be associated with increased risk of falling, but the results are inconsistent. The aim of this ...
    • The association between anthropometric measures of adiposity and the progression of carotid atherosclerosis 

      Imahori, Yume; Mathiesen, Ellisiv B.; Morgan, Katy E.; Frost, Chris; Hughes, Alun D.; Hopstock, Laila Arnesdatter; Johnsen, Stein Harald; Emaus, Nina; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-17)
      <i>Background</i> - Few reports are available on the contribution of general and abdominal obesity to the progression of carotid atherosclerosis in late adulthood. This study investigated the impact of four simple anthropometric measures of general and abdominal obesity on the progression of carotid atherosclerosis and the extent to which the association between adiposity and the progression of ...
    • Association between diastolic dysfunction and future atrial fibrillation in the Tromsø Study from 1994 to 2010 

      Tiwari, Sweta; Schirmer, Henrik; Jacobsen, Bjarne K.; Hopstock, Laila Arnesdatter; Nyrnes, Audhild; Heggelund, Geir; Njølstad, Inger; Mathiesen, Ellisiv B.; Løchen, Maja-Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-13)
      Objective. To investigate the association between echocardiographic measurements with emphasis on diastolic dysfunction and risk of atrial fibrillation (AF) in a population-based cohort study. Methods. We followed 2406 participants from the Tromsø Study from 1994 to 2010. Left atrial (LA) size and mitral Doppler indices as measured by echocardiography were used for evaluating diastolic dysfunction. ...
    • Association of C-reactive protein with future development of diabetes: A population-based 7-year cohort study among Norwegian adults aged 30 and older in the Tromsø Study 2007-2016 

      Tong, Kit I; Hopstock, Laila Arnesdatter; Cook, Sarah (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-29)
      Objectives The extent to which observed associations between high-sensitivity C-reactive protein (hs-CRP) and incident diabetes are explained by obesity and hypertension remains unclear. This study aimed to investigate the association of hs-CRP with developing diabetes in a Norwegian general population sample.<p> <p>Design A cohort study using two population-based surveys of the Tromsø Study: ...
    • Associations Between Intake of Fermented Dairy Products and Blood Lipid Concentrations Are Affected by Fat Content and Dairy Matrix - The Tromsø Study: Tromsø7 

      Machlik, Monika Lund; Hopstock, Laila Arnesdatter; Wilsgaard, Tom; Hansson, Patrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-22)
      Introduction: Dairy fat is rich in saturated fatty acids known to increase serum low-density lipoprotein cholesterol (LDL-C) concentration, an important risk factor for cardiovascular disease (CVD). However, intake of fermented dairy products has been associated with reduced CVD risk in observational studies. How intakes of different fermented dairy products are associated with blood lipid concentrations ...
    • Associations of serum 25-hydroxyvitamin D and subjective sleep measures in an arctic population: Insights from the population-based Tromsø Study 

      Uhlving Larsen, Anette; Hopstock, Laila Arnesdatter; Jorde, Rolf; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-06)
      Objective - To investigate the relation between serum 25-hydroxyvitamin D (s-25(OH)D) and subjective sleep measures in an Arctic population (69°N).<p> <p>Methods - Cross-sectional data was collected from 21,083 individuals (aged ≥40 years) participating in the population based Tromsø Study: Tromsø7 (2015–2016). The present study included 20,438 participants, after having excluded respondents ...
    • Atrial fibrillation is associated with cognitive decline in stroke-free subjects: the Tromsø Study 

      Tiwari, Sweta; Løchen, Maja-Lisa; Jacobsen, Bjarne K.; Hopstock, Laila Arnesdatter; Nyrnes, Audhild; Njølstad, Inger; Mathiesen, Ellisiv B.; Arntzen, Kjell Arne; Ball, Jocasta; Stewart, Simon; Wilsgaard, Tom; Schirmer, Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-28)
      Background and purpose:<br>Previous studies have shown associations between atrial fibrillation (AF) and cognitive decline. We investigated this association in a prospective population study, focusing on whether stroke risk factors modulated this association in stroke-free women and men.<br>Methods:<br>We included 4983 participants (57% women) from the fifth survey of the Tromsø Study (Tromsø 5, ...
    • A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain 

      Ho, Kevin Kwan Ngai; Skarpsno, Eivind S.; Nilsen, Kristian Bernhard; Ferreira, Paulo Herrique; Pinheiro, Marina; Hopstock, Laila Arnesdatter; Johnsen, Marianne Bakke; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Stubhaug, Audun; Simic, Milena (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-14)
      Objectives - To examine the possible bidirectional association between insomnia and comorbid chronic low back pain (LBP) and lower limb pain and to explore whether high-sensitivity C-reactive protein (hsCRP) amplifies these associations.<p> <p>Methods - We calculated adjusted risk ratios (RR) with 95% confidence intervals (CI) for the development of insomnia and mild-to-severe chronic LBP and ...
    • Blood pressure target achievement and antihypertensive medication use in women and men after first-ever myocardial infarction: the Tromsø Study 1994-2016 

      Hopstock, Laila Arnesdatter; Eggen, Anne Elise; Løchen, Maja-Lisa; Mathiesen, Ellisiv B.; Nilsen, Amalie; Njølstad, Inger; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-03)
      Background: <br> Recurrent cardiovascular events after myocardial infarction (MI) are frequent, and gender differences in blood pressure treatment have been reported. Despite increased focus on secondary prevention, recent reports indicate that treatment targets are not achieved. There is a need for gender-specific analyses of post-MI blood pressure treatment target achievement and ...
    • Body mass index, waist circumference and pre-frailty/frailty: the Tromsø study 1994−2016 

      Uchai, Shreeshti; Andersen, Lene Frost; Hopstock, Laila Arnesdatter; Hjartåker, Anette (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-23)
      Objective This study investigated the association between obesity, assessed using body mass index (BMI) and waist circumference (WC), and pre-frailty/frailty among older adults over 21 years of follow-up. <p>Design Prospective cohort study. <p>Setting Population-based study among communitydwelling adults in Tromsø municipality, Norway. <p>Participants 2340women and 2169 men aged ≥45 years ...
    • Cardiopulmonary resuscitation; use, training and self-confidence in skills : a self-report study among hospital personnel 

      Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-12-16)
      Background: Immediate start of basic cardiopulmonary resuscitation (CPR) and early defibrillation have been highlighted as crucial for survival from cardiac arrest, but despite new knowledge, new technology and massive personnel training the survival rates from in-hospital cardiac arrest are still low. National guidelines recommend regular intervals of CPR training to make all hospital personnel ...
    • CHA2DS2-VASc score, left atrial size and atrial fibrillation as stroke risk factors in the Tromsø Study 

      Tiwari, Sweta; Løchen, Maja-Lisa; Jacobsen, Bjarne K.; Hopstock, Laila Arnesdatter; Nyrnes, Audhild; Njølstad, Inger; Mathiesen, Ellisiv B.; Schirmer, Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-01)
      Objective:<br> CHA2DS2-VASc score, left atrial (LA) size and atrial fibrillation (AF) have individually been associated with stroke risk. Our aim was to investigate the predictive ability of combinations of these factors for the odds of incident stroke in a population-based cohort study.<br> Methods:<br> We followed 2844 participants from the Tromsø Study from 1994 to 2012. Information on LA size ...
    • Changes in adiposity, physical activity, cardiometabolic risk factors, diet, physical capacity and well-being in inactive women and men aged 57-74 years with obesity and cardiovascular risk – A 6-month complex lifestyle intervention with 6-month follow-up 

      Hopstock, Laila Arnesdatter; Deraas, Trygve Sigvart; Henriksen, André; Martiny-Huenger, Torsten; Grimsgaard, Sameline (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-25)
      A key challenge in lifestyle interventions is long-term maintenance of favorable lifestyle changes. Middle-aged and older adults are important target groups. The purpose of this analysis was to investigate changes in adiposity, physical activity, cardiometabolic risk factors, diet, physical capacity, and well-being, in inactive middle-aged and older women and men with obesity and elevated cardiovascular ...
    • Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. 

      Cook, Sarah; Eggen, Anne Elise; Hopstock, Laila Arnesdatter; Malyutina, S; Shapkina, M; Kudryavtsev, Alexander V; Melbye, Hasse; Quint, JK (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-14)
      Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Despite a high prevalence of smoking and respiratory symptoms, two recent population-based studies in Russia found a relatively low prevalence of obstructive lung function. Here, we investigated the prevalence of both obstructive lung disease and respiratory symptoms in a population-based ...
    • Clustering and trajectories of key noncommunicable disease risk factors in Norway: the NCDNOR project 

      Dalene, Knut Eirik; Lergenmuller, Simon; Sund, Erik Reidar; Hopstock, Laila Arnesdatter; Robsahm, Trude Eid; Nilssen, Yngvar; Nystad, Wenche; Larsen, Inger Kristin; Ariansen, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-02)
      Noncommunicable diseases (NCDs) are a leading cause of premature death globally and have common preventable risk factors. In Norway, the NCDNOR-project aims at establishing new knowledge in the prevention of NCDs by combining information from national registries with data from populationbased health studies. In the present study, we aimed to harmonize data on key NCD risk factors from the health ...
    • Comparing prevalence of chronic kidney disease and its risk factors between population-based surveys in Russia and Norway 

      Cook, Sarah; Solbu, Marit Dahl; Eggen, Anne Elise; Iakunchykova, Olena; Averina, Maria; Hopstock, Laila Arnesdatter; Kholmatova, Kamila Kahramonzhonovna; Kudryavtsev, Alexander V; Leon, David A.; Malyutina, Sofia; Ryabikov, Andrew; Williamson, Elizabeth; Nitsch, Dorothea (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-14)
      Background - Little data exists on the prevalence of chronic kidney disease (CKD) in the Russian population. We aimed to estimate the prevalence of CKD in a population-based study in Russia, compare with a similar study in Norway, and investigate whether differences in risk factors explained between-study differences in CKD.<p> <p>Methods - We compared age- and sex-standardised prevalence of ...
    • Complex lifestyle intervention among inactive older adults with elevated cardiovascular disease risk and obesity: a mixed-method, single-arm feasibility study for RESTART—a randomized controlled trial 

      Deraas, Trygve Sigvart; Hopstock, Laila Arnesdatter; Henriksen, André; Morseth, Bente; Sand, Anne-Sofie; Njølstad, Inger; Pedersen, Sigurd; Sagelv, Edvard Hamnvik; Johansson, Jonas; Grimsgaard, Sameline (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-27)
      Background - Physical inactivity and obesity are global public health challenges. Older adults are important to target for prevention and management of disease and chronic conditions. However, many individuals struggle with maintaining increased physical activity (PA) and improved diet. This feasibility study provides the foundation for the RESTART trial, a randomized controlled trial (RCT) to test ...