Background This study aims to assess the efficacy and safety of Qingpeng ointment (QPO), a Tibetan medicine for alleviating symptoms in individuals with acute gouty arthritis (AGA).<p> <p>Methods This study was a randomized, double-blind, placebo-controlled trial that involved individuals with AGA whose joint pain, as measured on a visual analog scale (VAS) from 0 to 10, was equal to or greater ...

<p><i>Background:</i> Noncommunicable diseases (NCDs) such as cancer and cardiovascular diseases (CVDs) are predominant causes of mortality in Norwegian women. With a national goal to reduce premature mortality from NCDs by 33% by 2030, Norway is also committed to achieving Sustainable Development Goals, including those related to climate change. The Food and Agriculture Organization (FAO) emphasizes ...

This paper outlines the methodological approaches to a multi-site Circumpolar case study exploring the impacts of COVID-19 on Indigenous and remote communities in 7 of 8 Arctic countries. Researchers involved with the project implemented a three-phase multi-site case study to assess the positive and negative societal outcomes associated with the COVID-19 pandemic in Arctic communities from ...

This thesis focuses on group mentorship for undergraduate medical students as a pivotal element in fostering a supportive and collaborative learning environment, essential for the complex field of medicine. Previous studies have mostly focused on one-on-one mentoring. Group mentorships can foster a collaborative and reflective environment in which students can benefit from the collective knowledge ...

Arctic miners face significant risks from diesel exhaust and dust exposure, potentially leading to adverse respiratory health. Employers must limit harmful exposures, using personal protective equipment (PPE) as a last line of defense. This study explored the association between reported respiratory exposure and symptoms, and PPE training and usage. Data from the MineHealth study (2012–2014) ...

The literature on Raynaud’s phenomenon (RP) in the feet is scarce, especially in the occupational setting. The primary aim of our study was to investigate the occurrence of RP in the feet of miners. As part of the MineHealth project, written surveys and clinical examinations were completed by 260 Arctic open-pit miners working in northern Sweden and Norway (participation rate 53.6%). Data on ...

Background The identification of cell type-specific genes and their modification under different conditions is central to our understanding of human health and disease. The stomach, a hollow organ in the upper gastrointestinal tract, provides an acidic environment that contributes to microbial defence and facilitates the activity of secreted digestive enzymes to process food and nutrients into ...

<p><i>Background</i> Interactions between the gut microbiota, diet, and host metabolism contribute to the development of cardiovascular disease, but a firm link between disease-specific gut microbiota alterations and circulating metabolites is lacking. <p><i>Methods</i> We performed shot-gun sequencing on 235 samples from 166 HF patients and 69 healthy control samples. Separate plasma samples from ...

Bakgrunn: Hjerneslag defineres som en plutselig oppstått fokal eller global forstyrrelse i hjernens funksjoner som vedvarer i mer enn 24 timer og som har vaskulær årsak. Et TIA (transitorisk iskemisk anfall) er tradisjonelt definert på samme måte som et hjerneslag, men med varighet under 24 timer. Denne tidsbaserte definisjonen gjenspeiler i liten grad patofysiologien ved hjerneslag og TIA. Ved økt ...

Metakromatisk leukodystrofi er en autosomal recessiv arvelig nevrodegenerativ sykdom, hvor myelinet rundt nervefibrene i både det sentrale og det perifere nervesystemet destrueres. Dette resulterer i progressiv motorisk, sensorisk og kognitiv svikt. Sykdommen er forårsaket av mangel på arylsulfatase A lysosomale enzym og sfingolipid aktivator protein B, som en konsekvens av bialleliske mutasjoner i ...