Now showing items 1-20 of 30

    • Antibiotic resistance profiles and polystyrene biofilm formation capabilities of bacteria isolated from wastewater in Tromsø 

      Imani, Sharifa Buchana (Master thesis; Mastergradsoppgave, 2021-05-18)
      Pollution of plastic in itself has become a growing focus in the last 15 years. In addition, the impact of plastic as a reservoir for pathogenic bacteria and transfer of antibiotic resistance genes has become a global concern, for individuals, organizations, policymakers and health organizations. It is important to document the relationship of microbiota associated to different types of plastic ...
    • Antimikrobielle forbindelser fra de to subarktiske sjøpungene : Synoicum turgens og Synoicum incrustatum 

      Hansen, Ida Kristine (Master thesis; Mastergradsoppgave, 2011-05-16)
      To arter sjøpung fra subarktiske strøk, Synoicum turgens og Synoicum incrustatum, ble testet for antibakteriell aktivitet. Prøvene ble ekstrahert med 60% acetonitril + 0.1% trifluoreddiksyre, og videre renset med fast fase ekstraksjon (SPE). Disse ble testet for antibakteriell aktivitet, og videre fraksjonert ved høytrykks-væskekromatografi (HPLC). HPLC fraksjonene ble testet for aktivitet, hvor ...
    • Antimikrobielle forbindelser i marine diatomeer (kiselalger) 

      Osvik, Renate Døving (Master thesis; Mastergradsoppgave, 2013-05-15)
      Bioprospektering er definert som leting etter og karakterisering av nye bioaktive forbindelser fra naturens ressurser med den hensikt å benytte denne kunnskapen kommersielt til utvikling av medisiner, helsekost eller stoffer med annen anvendelse. Blant moderne medisiner er hele 40% basert kunnskap fra naturstoffer, og blant kreftmedisiner og medisiner mot infeksiøse sykdommer er andelen enda høyere. ...
    • Antimikrobielle peptider i O-skjell, Modiolus modiolus 

      Rødum, Inger Kristine (Master thesis; Mastergradsoppgave, 2015-05-29)
      I en tidligere studie utført på O-skjell (Modiolus modiolus) har antimikrobiell aktivitet blitt påvist i en rekke vevekstrakter, deriblant fra hemocyttene. En videreføring av dette arbeidet har ført til isoleringen av flere antimikrobielle peptider samt karakterisering av partielle N-terminale sekvenser. Dette masterprosjektet har hatt som hensikt å følge opp disse funnene ytterligere ved å påvise ...
    • Assessing the effect of salmon aquaculture on fungal diversity in seawater and sediments through eDNA metabarcoding 

      Husanovic, Elmedina (Master thesis; Mastergradsoppgave, 2021-05-16)
      Fungi have been found to play important roles in marine ecosystems, e.g., symbionts of plants and animals, and as decomposers of organic materials. The fungal communities, however, are often considered less studied and their functional and taxonomic diversity in aquatic environments remains poorly understood. Since the 1970s the Norwegian salmon industry developed from a small-scale industry to ...
    • Bioactivity evaluation of underutilized marine raw materials for the management of metabolic syndrome 

      Rauø, Njål (Master thesis; Mastergradsoppgave, 2021-05-15)
      Metabolic syndrome (MetS) is the medical term for a cluster of risk factors including obesity, high blood pressure, and high blood sugar, which increases the risk of developing stroke, heart disease, and type 2 diabetes. Marine raw materials have been described to exert various bioactive properties beneficial to human health, including anti-inflammatory, antioxidant, and antidiabetic abilities. In ...
    • Bioactivity Potential of an Arctic Marine Diatom Species Cultivated at Different Conditions 

      Elvedal, Ida (Master thesis; Mastergradsoppgave, 2018-05-15)
      Microalgae have proven to contain a vast amount of beneficial, high value compounds like proteins, lipids and powerful antioxidants as well as some interesting bioactive compounds. Nevertheless, microalgae are severely underrepresented in conjunction with marine bioactive natural product discovery. This thesis aims to unlock bioactivity potential of a microalgae species from the most abundant and ...
    • Biodiscovery of Novel RNA Ligases with Biotechnological Potential - New Insights into the RNA Ligase 3 Family 

      Gábor, Hannah Ildikó Johnstad (Master thesis; Mastergradsoppgave, 2020-08-04)
      Polynucleotide ligases constitute a class of enzymes which catalyse the formation of phosphodiester bonds between proximal 5’-PO4 and 3’-OH groups in DNA, RNA and DNA/RNA-hybrid substrates. The reaction proceeds through three steps, where steps 1 and 2 prepare the substrate for ligation in step 3. The focus of this thesis is on ssRNA ligases of the RNA ligase (Rnl) 3 family. RNA ligases can repair ...
    • Biokjemiske egenskaper til grakse fra produksjon av Calanus® Oil 

      Sjøvoll, Anja (Master thesis; Mastergradsoppgave, 2017-05-15)
      Det er et stort behov for nye marine lipidkilder med et høyt innhold av LC-PUFA. Den store biomasseproduksjonen av raudåte (Calanus finmarchicus) i Norskehavet gjør den unik. Fra raudåte utvinner firmaet Calanus AS den kommersielle oljen Calanus® Oil. Gjennom prosessen dannes også to andre produkter, et proteinhydrolysat og en grakse (presskake). Det overordnede målet med masteroppgaven var å ...
    • Chemical and Enzyme-Assisted Extraction of Fucoidan from two Species of Brown Macroalgae (Ascophyllum nodosum and Saccharina latissima) 

      Maribu, Ingrid (Master thesis; Mastergradsoppgave, 2021-05-18)
      Marine environments contain half of the global biodiversity and are a major source of bioactive compounds. Macroalgae are vital species in marine ecosystems and are known to produce several bioactive compounds and polysaccharides that possesses several bioactivities. These molecules are traditionally extracted using methods that heavily rely on hazardous solvents and heat, that more importantly ...
    • CO2 i sjø og på land. En lokal studie med fokus på fabrikkrøyk og miljø. 

      Øyen, Frode Jacobsen (Master thesis; Mastergradsoppgave, 2019-11-15)
      Netto utslipp av karbon til atmosfæren har økt siden starten på den industrielle revolusjon. Rundt halvparten av karbon som slippes ut blir tatt opp av havet fysisk via karbon fluks eller bundet opp i økosystemer i havet eller på land. Denne oppgaven tolker og diskuterer potensielle lokale virkninger av industriell CO2 utslipp ved å benytte fysiske og biologiske, oseanografi og CO2 data samlet ...
    • A Comparison of Biochemical Composition and Bioactivity of Abalone (Haliotis spp) Subjected to Different Diets and Treatments 

      Opara, Uchenna Ben (Master thesis; Mastergradsoppgave, 2021-03-01)
      The fast growth of the aquaculture sector has led to an unsustainable harvest of wild fish species used in the production of aquaculture feed. Integrated Multi-trophic Aquaculture (IMTA) promises ecological and socio-economic advantages that include the provision of sustainable aquaculture feed. However, the promotion of IMTA requires that the stakeholders have sufficient quantitative information ...
    • Design av en transkripsjonssensor i Escherichia coli : til deteksjon av virkningsmåten til nyoppdagede antimikrobielle peptider 

      Bjørsvik, Magnus Støback (Master thesis; Mastergradsoppgave, 2013-05-15)
      Antibiotikaresistens er vurdert som den største trusselen knyttet til behandling av de smittsomme sykdommene i den vestlige verden, på grunn av økningen i infeksjoner som følge av multiresistente bakterier. Nylige sykdomsutbrudd forårsaket av bakterier med total eller delvis resistens mot tilgjengelige antibiotika, kan være meget alvorlige siden mulighetene for behandling er svært begrenset. Marin ...
    • Effekter på bakteriesamfunn av boreslamdeponering på havbunnen 

      Øverleir, Ida Maylen (Master thesis; Mastergradsoppgave, 2014-05-15)
      Som en del av Barents Sea Drill Cuttings Research Initiative (BARCUT) fokuserte denne masteroppgaven på å avdekke om bakteriesammensetningen i sedimentet rundt en borebrønn påvirkes av boreavfallsdeponeringer. Under tokt med M/S «Njord Viking» 30. november – 3. desember 2013 ble det hentet opp kjerneprøver ved en letebrønn i Brønnlokaliteten. Dette ble gjort samtidig med at Akvaplan-niva gjennomførte ...
    • Enzymatic protein hydrolysis of residual raw material from Atlantic cod: Selectivity of proteases, outcome and bioactivities 

      Sorokina, Liudmila (Master thesis; Mastergradsoppgave, 2020-08-14)
      Global trends show that interest in fish products and fish consumption are increasing, while marine fishery resources are decreasing. Fish processing industry produces a high amount of residual raw materials that have nutritious proteins and other valuable compounds. An optimization of residual raw materials’ utilization can help meet the growing demand for fish products and help reduce environmental ...
    • Exploring the antibacterial and anticancer potential of five marine fungi. With the use of OSMAC-approach 

      Bragmo, Hanne (Master thesis; Mastergradsoppgave, 2017-05-15)
      The marine environment is an untapped source for biodiversity and has a great potential to provide the drugs of the future. Antibiotic resistance is an increasing threat worldwide and the need for discovering new antibacterial compounds is urgent. Marine microorganisms produce a wide range of bioactive compounds, and marine fungi have only been exploited to a small extent. This creates a great ...
    • Exploring the potential of two arctic marine bacteria for the production of bioactive metabolites 

      Jenssen, Marte (Master thesis; Mastergradsoppgave, 2017-05-15)
      The number of compounds being isolated from the marine environment is increasing, and there is a great potential for discovering new marine derived drug candidates. Improved collection techniques has strengthened bioprospecting on a wider diversity of marine microorganisms. The focus on microorganisms has led to the realisation that many of the natural products originally isolated from macroorganisms, ...
    • Expression of Secondary Metabolite Gene Clusters and Production of Secondary Metabolites in Three Nostoc strains Subjected to Deprivation on Nutrients and Competition 

      Wilhelmsen, Oda Sofie Bye (Master thesis; Mastergradsoppgave, 2019-05-15)
      Cyanobacteria are a unique source of natural products, where most of them are synthesized by non-ribosomal peptide synthase, polyketide synthase, or a hybrid of these pathways. The identification of such biosynthetic genes responsible for the production of secondary metabolites is still a relatively unexplored area, and it remains many natural products for which a biosynthetic origin is unknown. ...
    • From Lab to Industry - Enzymes from Undifferentiated Marine Rest Raw Material 

      Steinsholm, Silje (Master thesis; Mastergradsoppgave, 2014-05-15)
      The aim of this project was to optimize the extraction of esterase enzymes from undifferentiated herring rest raw material. This was conducted by comparing, in laboratory scale, the outcome of using homogenised and non-homogenised raw material, and by extracting with buffers of different pH. Further on, clarification experiments of flocculation were performed on the optimal extract. The focus was ...
    • Genomic characterization and insights of local adaptation in Norwegian juvenile lumpfish populations 

      Granviken, Emilie Østby (Master thesis; Mastergradsoppgave, 2021-05-18)
      The lumpfish (Cyclopterus lumpus Linnaeus, 1758) has for many years been an attractive target for the roe fisheries in Norway and has more recently become an important cleanerfish in the salmonid farming industry for the control of salmon lice (Copepoda: Caligidae). Despite this, there is a lack of knowledge about several life aspects of the species and studies on its genetic structure have been ...