Blar i forfatter Institutt for psykologi "Hegstad, Jan"

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    • Can perinatal SSRI exposure affect sexual behavior later in life? Early Developmental Fluoxetine Exposed Female Rats Observed in a Seminatural Environment 

      Hegstad, Jan (Master thesis; Mastergradsoppgave, 2019-05-02)
      Renewed interests in sexual behavior research stems from human reports of negative symptoms of selective serotonin reuptake inhibitor (SSRI). The use of SSRIs, during pregnancy might impact the developing child, due to the drug’s ability to cross the placenta and also be present in breastmilk. Perinatal SSRI exposure thus elevates serotonin levels in the developing brain, during phases where serotonin ...

    • Female rat sexual behavior is unaffected by perinatal fluoxetine exposure 

      Hegstad, Jan; Huijgens, Patty Thalia; Houwing, Danielle; Olivier, Jocelien; Heijkoop, Roy; Snoeren, Eelke (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-22)
      Serotonin plays an important role in adult female sexual behavior, however little is known about the influence of serotonin during early development on sexual functioning in adulthood. During early development, serotonin acts as neurotrophic factor, while it functions as a modulatory neurotransmitter in adulthood. The occurrence of serotonin release, could thus have different effects on behavioral ...