Blar i forfatter Institutt for psykologi "Houwing, Danielle"

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    • Effects of perinatal fluoxetine exposure on novelty-induced social and non-social investigation behaviors in a seminatural environment 

      Sylte, Ole Christian; Johansen, Jesper Solheim; Heinla, Indrek; Houwing, Danielle; Olivier, Jocelien D.A.; Heijkoop, Roy; Snoeren, Eelke (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-23)
      Selective serotonin reuptake inhibitors (SSRIs) are increasingly prescribed as medication for various afective disorders during pregnancy. SSRIs cross the placenta and afect serotonergic neurotransmission in the fetus, but the neurobehavioral consequences for the ofspring remain largely unclear. Recent rodent research has linked perinatal SSRI exposure to alterations in both social and non-social ...

    • Female rat sexual behavior is unaffected by perinatal fluoxetine exposure 

      Hegstad, Jan; Huijgens, Patty Thalia; Houwing, Danielle; Olivier, Jocelien; Heijkoop, Roy; Snoeren, Eelke (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-22)
      Serotonin plays an important role in adult female sexual behavior, however little is known about the influence of serotonin during early development on sexual functioning in adulthood. During early development, serotonin acts as neurotrophic factor, while it functions as a modulatory neurotransmitter in adulthood. The occurrence of serotonin release, could thus have different effects on behavioral ...

    • Perinatal fluoxetine exposure changes social and stress-coping behavior in adult rats housed in a seminatural environment 

      Houwing, Danielle; Heijkoop, Roy; Olivier, Jocelien; Snoeren, Eelke (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-06)
      The use of selective serotonin reuptake inhibitors (SSRI) during pregnancy has increased tremendously, but the consequences for the offspring remain largely unclear. Several studies have described potential effects of perinatal SSRI-exposure on neurobehavioral outcomes using simplified rodent test set-ups, however these set-ups only assess a small fraction of the behavior. For translational purposes ...

    • Third-party prosocial behavior in adult female rats is impaired after perinatal fluoxetine exposure 

      Heinla, Indrek; Heijkoop, Roy; Houwing, Danielle; Olivier, Jocelien; Snoeren, Eelke (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-26)
      SSRIs are commonly used to treat pregnant women with depression. However, SSRIs can cross the placenta and affect the development of the fetus. The effects of perinatal SSRI exposure, and especially the effects on social behavior, are still incompletely documented. This study first aims to investigate whether rats show prosocial behavior in the form of consolation behavior. Secondly, it aims to ...