Blar i forfatter Institutt for psykologi "Kirsebom, Bjørn-Eivind Seljelid"

Viser treff 1-5 av 5

    • Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults 

      Hemminghyth, Mathilde Suhr; Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Gisladottir, Berglind; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner; Rongve, Arvid; Fladby, Tormod; Kirsebom, Bjørn-Eivind Seljelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)
      Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a marker of neuronal body injury) and neurofilament light chain (NfL, a marker of axonal injury) show age-related increases in normal aging. In the current study, we aimed to investigate ...

    • Demographically adjusted Rey–Osterrieth Complex Figure Test norms in a Swedish and Norwegian cohort aged 49–77 years and comparison with North American norms 

      Öhman, Fredrik; Eckerström, Marie; Hessen, Erik; Espenes, Johan Jacob; Eliassen, Ingvild Vøllo; Lorentzen, Ingrid Myrvoll; Stålhammar, Jacob; Kettunen, Petronella; Schöll, Michael; Fladby, Tormod; Wallin, Anders; Kirsebom, Bjørn-Eivind Seljelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-18)
      Introduction The Rey–Osterrieth Complex Figure Test (RCFT) is one of the most commonly used neuropsychological tests in Sweden and Norway. However, no publications provide normative data for this population. The objective of this study was to present demographically adjusted norms for a Swedish and Norwegian population and to evaluate these in an independent comparison group.<p> <p>Methods The ...

    • A Knowledge Graph Framework for Dementia Research Data 

      Timón, Santiago; Rincón, Mariano; Martínez-Tomás, Rafael; Kirsebom, Bjørn-Eivind Seljelid; Fladby, Tormod (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-20)
      Dementia disease research encompasses diverse data modalities, including advanced imaging, deep phenotyping, and multi-omics analysis. However, integrating these disparate data sources has historically posed a significant challenge, obstructing the unification and comprehensive analysis of collected information. In recent years, knowledge graphs have emerged as a powerful tool to address such ...

    • Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease 

      Nordengen, Kaja; Kirsebom, Bjørn-Eivind Seljelid; Richter, Grit; Pålhaugen, Lene; Gisladottir, Berglind; Siafarikas, Nikias Ioannis; Nakling, Arne Exner; Rongve, Arvid; Bråthen, Geir; Grøntvedt, Gøril Rolfseng; Gonzalez, Fernando; Waterloo, Knut; Sharma, Kulbhushan; Karikari, Thomas; Vromen, Eleonora M.; Tijms, Betty M.; Visser, Pieter J.; Selnes, Per; Kramberger, Milicia G.; Winblad, Bengt; Blennow, Kaj; Fladby, Tormod (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-13)
      Background - Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal clinical studies that include biomarker negative healthy controls and cases with established AD pathology. Here, we employ longitudinally sampled cerebrospinal fluid (CSF) core AD, ...

    • Regression-based normative data for the D-KEFS Color-Word Interference Test in Norwegian adults ages 20–85 

      Espenes, Johan Jacob; Lorentzen, Ingrid Myrvoll; Eliassen, Ingvild Vøllo; Hessen, Erik; Waterloo, Knut K; Timón, Santiago; Fladby, Tormod; Walhovd, Kristine Beate; Fjell, Anders Martin; Kirsebom, Bjørn-Eivind Seljelid (Journal article; Tidsskriftartikkel, 2023-11-16)
      <p><i>Objective:</i> The Delis-Kaplan Executive Function System (D-KEFS) Color-Word-Interference Test (CWIT; AKA Stroop test) is a widely used measure of processing speed and executive function. While test materials and instructions have been translated to Norwegian, only American age-adjusted norms from D-KEFS are available in Norway. We here develop norms in a sample of 1011 Norwegians between 20 ...