Acute heart failure (AHF) is a disease with a mortality ranging from 5 to 40% depending on severity, despite modern revascularization techniques after acute myocardial thromboembolism. In this thesis we have investigated two new concepts of treating AHF. In paper 1 we investigated the combination of dobutamine and ivabradine (D+I) in a porcine model of stunning AHF. Ivabradine attenuated the ...