Blar i forfatter Doktorgradsavhandlinger (Helsefak) "Mørtberg, Trude Victoria"
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Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia (FNAIT) by prophylactic monoclonal antibodies. In vitro and preclinical evaluation of HPA-1a-specific antibodies
Mørtberg, Trude Victoria (Doctoral thesis; Doktorgradsavhandling, 2023-10-19)The focus of this thesis is the condition fetal/neonatal alloimmune thrombocytopenia (FNAIT) where maternal alloantibodies toward paternally inherited human platelet antigens (HPAs) cause depletion of fetal platelets. Clinical outcomes are heterogenous and can be asymptomatic, mild or severe bleedings, where intracranial hemorrhage (ICH) is the feared outcome as it may lead to lifelong disabilities ...