Rixon, Chloe Louise; Andreassen, Kristine; Shen, Xin; Murugan Erusappan, Pugazendhi; Almaas, Vibeke Marie; Palmero, Sheryl; Dahl, Christen Peder; Ueland, Thor; Sjaastad, Ivar; Louch, William Edward; Stokke, Mathis Korseberg; Tønnessen, Theis; Christensen, Geir; Lunde, Ida Gjervold (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-29)
Aims Familial hypertrophic cardiomyopathy (HCM) is the most common form of inherited cardiac disease. It is characterized
by myocardial hypertrophy and diastolic dysfunction, and can lead to severe heart failure, arrhythmias, and sudden cardiac
death. Cardiac fibrosis, defined by excessive accumulation of extracellular matrix (ECM) components, is central to the pathophysiology of HCM. The ECM ...