Pseudomonas aeruginosa is capable of thriving in diverse environments due to its network of regulatory components for effective response to stress factors. The survival of the bacteria is also dependent on the ability to discriminate between the acquisition of beneficial and non-beneficial genetic materials via horizontal gene transfer (HGT). Thus, bacteria have evolved the CRISPR-Cas adaptive immune ...

Objective: Patients with hip fracture are at high risk of medication errors due to a combination of high age, comorbidities, polypharmacy and several care transitions after fracture. The aim was to study medication management tasks concerning patient safety: medication reconciliation, medication review and communication of key medication information in care transitions. Design: Descriptive study ...

Background - Decision coaching is non-directive support delivered by a trained healthcare provider to help people prepare to actively participate in making healthcare decisions. This study aimed to understand how and under what circumstances decision coaching works for people making healthcare decisions.<p> <p>Methods - We followed the realist review methodology for this study. This study was ...

Quorum sensing (QS) coordinates bacterial communication and cooperation essential for virulence and dominance in polymicrobial settings. QS also regulates the CRISPR-Cas system for targeted defense against parasitic genomes from phages and horizontal gene transfer. Although the QS and CRISPR-Cas systems are vital for bacterial survival, they undergo frequent selection in response to biotic and abiotic ...

Meteor radars have become widely used instruments to study atmospheric dynamics, particularly in the 70 to 110 km altitude region. These systems have been proven to provide reliable and continuous measurements of horizontal winds in the mesosphere and lower thermosphere. Recently, there have been many attempts to utilize specular and/or transverse scatter meteor measurements to estimate vertical ...

Background - Breast cancer risk remains higher in high-income compared with low-income countries. However, it is unclear to what degree metabolic factors influence breast cancer development in women 30 years after immigration from low- to a high-incidence country.<p> <p>Methods - Using Cox regression models, we studied the association between pre-diagnostic metabolic factors and breast cancer ...

The redox behaviour of bidentate (BID) ligands containing either two O donor atoms (O,O’-BID ligand), a N and an O donor atom (N,O-BID ligand) or two N donor atoms (N,N’-BID ligand), and their rhodium complexes, are presented. The experimental reduction potential of the L,L’-BID ligands (L,L’ = N and O) and the experimental oxidation potential of [Rh(L,L’-BID)(CO)(PPh₃)] complexes relate ...

We explore the implementation and development of individual placement and support (IPS) in Norway. IPS is an evidence-based practice for supporting people experiencing mental illness to obtain and maintain competitive employment. Implementation of IPS into routine practice has been challenged by different paradigms in vocational rehabilitation, health and welfare policies. Data were mainly collected ...

Epidemiological literature on the relationship between physical activity and chronic pain is scarce and inconsistent. Hence, our aim was to assess the relationship applying comprehensive methodology, including self-reported and accelerometer measures of physical activity and different severity levels of chronic pain. We used data from the Tromsø Study (2015-2016). All residents in the municipality, ...

Background: Post-COVID-19 condition is frequently comprised of persistent cognitive sequela, including deficits in attention and executive functions (EFs), which can act as a barrier for regaining pre-illness functional levels. Goal Management Training (GMT) is a cognitive rehabilitation (CR) intervention for improving attention and EFs that has received empirical support in studies of other ...