Objectives<p> Opioids are the most potent analgesics in the treatment of postoperative pain. Respiratory depression is, however, a serious side effect. The aims of this study were to evaluate current practice and routines for post-operative administration of opioids in a Norwegian university hospital and to evaluate whether the clinical safeguards adequately protected patients’ safety regarding risk ...

This article discusses methodological aspects of an ongoing research project on Kven worldings. The work is inspired by Donna Haraway’s perspectives on situated research. A metalogue, where the authors share reflections and discuss their maneuvers as researchers, makes visible some of the ontological and epistemological troubles the researchers are facing related to the philosophical research approach, ...

Monomineralic millimeter-sized olivine nodules are common in kimberlites worldwide. It is generally thought that such ‘dunitic nodules’ originate from the base of the cratonic lithosphere and that their formation marks the onset of deep-rooted kimberlite magmatic plumbing systems. However, thermobarometric constraints to support such a model have been lacking thus far. This study focuses on the ...

Background - The aim of the present study was to investigate the associations stroke severity, aphasia severity, lesion location and lesion size in acute stroke, and aphasia severity in the subacute and chronic stages post stroke. We hypothesized that initial stroke severity and aphasia severity were associated with the patient’s aphasia severity in the subacute and chronic stages of stroke. We ...

The complement system was discovered at the end of the 19th century as a heat-labile plasma component that “complemented” the antibodies in killing microbes, hence the name “complement.” Complement is also part of the innate immune system, protecting the host by recognition of pathogen-associated molecular patterns. However, complement is multifunctional far beyond infectious defense. It contributes ...

Linear logic models are insufficient to understand how interventions work in complex areas such as sustainable tourism. We present Participatory Systems Mapping (PSM), a novel method to develop shared understandings and collective management of complex policy issues among stakeholders. We use PSM with stakeholders in Barcelona to support the design of an upcoming evaluation of an existing sustainability ...

Background: Whole body ischemia and reperfusion injury after cardiac arrest leads to the massive inflammation clinically manifested in the post-cardiac arrest syndrome. Previous studies on the inflammatory effect on circulatory failure after cardiac arrest have either investigated a selected patient group or a limited part of the inflammatory mechanisms. We examined the association between cardiac ...

Trophic interactions are crucial for carbon cycling in food webs. Traditionally, eukaryotic micropredators are considered the major micropredators of bacteria in soils, although bacteria like myxobacteria and Bdellovibrio are also known bacterivores. Until recently, it was impossible to assess the abundance of prokaryotes and eukaryotes in soil food webs simultaneously. Using metatranscriptomic ...

Background: Inflammation has been linked to prostate cancer and hypertension, but it remains equivocal whether elevated blood pressure (BP) influence prostate cancer risk and survival.<p> <p>Method: Using Cox regression models, we examined the association between prediagnostic BP and prostate cancer risk among 12,271 men participating in the Prostate Cancer throughout life (PROCA-life) study. ...