Artikler, rapporter og annet (UB): Nye registreringer
Viser treff 1521-1540 av 3249
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Geographical variation in ADHD: do diagnoses refect symptom levels?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-18)Rates of ADHD diagnosis vary across regions in many countries. However, no prior study has investigated how much within-country geographic variation in ADHD diagnoses is explained by variation in ADHD symptom levels. We examine whether ADHD symptom levels explain variation in ADHD diagnoses among children and adolescents using nationwide survey and register data in Norway. Geographical variation in ... -
High abundances of small copepods early developmental stages and nauplii strengthen the perception of a non-dormant Arctic winter
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-15)The traditional view is that the Arctic polar night is a quiescent period for marine life, but recent reports of high levels of feeding and reproduction in both pelagic and benthic taxa have challenged this. We examined the zooplankton community present in Svalbard fjords, coastal waters, and the shelf break north of Svalbard, during the polar night. We focused on the population structure of abundant ... -
Trends in Hip Fracture Incidence, Length of Hospital Stay, and 30-Day Mortality in Sweden from 1998–2017: A Nationwide Cohort Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-15)In this nationwide cohort study, we investigated trends in hip fracture incidence, hospital length of stay (LOS), and 30-day mortality after admission in Sweden. The cohort included all individuals in Sweden aged ≥ 50 years with a first hip fracture diagnosis during 1998–2017 (N = 313,761). The outcomes were hip fracture incidence and 30-day mortality. The results showed that the incidence of hip ... -
Whole-body MRI in children aged 6–18 years. Reliability of identifying and grading high signal intensity changes within bone marrow
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-21)Background - Whole-body magnetic resonance imaging (MRI) is increasingly being used in children, however, to date there are no studies addressing the reliability of the findings.<p> <p>Objective - To examine intra- and interobserver reliability of a scoring system for assessment of high signal areas within the bone marrow, as visualized on T2-weighted, fat-saturated images.<p> <p>Materials and ... -
Factors associated with excess all-cause mortality in the first wave of the COVID-19 pandemic in the UK: A time series analysis using the Clinical Practice Research Datalink
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-06)Background: Excess mortality captures the total effect of the Coronavirus Disease 2019 (COVID-19) pandemic on mortality and is not affected by misspecification of cause of death. We aimed to describe how health and demographic factors were associated with excess mortality during, compared to before, the pandemic. <p> <p>Methods and findings: We analysed a time series dataset including 9,635,613 ... -
Risk factors for breast cancer, including occupational exposures
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013-07-17)The knowledge on the etiology of breast cancer has advanced substantially in recent years, and several etiological factors are now fi rmly established. However, very few new discoveries have been made in relation to occupational risk factors. The International Agency for Research on Cancer has evaluated over 900 different exposures or agents to-date to determine whether they are carcinogenic to ... -
Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-22)Background Although 10000 steps per day is widely promoted to have health benefits, there is little evidence to support this recommendation. We aimed to determine the association between number of steps per day and stepping rate with all-cause mortality.<p> <p>Methods In this meta-analysis, we identified studies investigating the effect of daily step count on all-cause mortality in adults (aged ... -
EMMPRIN is associated with S100A4 and predicts patient outcome in colorectal cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-07-10)BACKGROUND: Proteolytic enzymes and their regulators have important biological roles in colorectal cancer by stimulating invasion and metastasis, which makes these factors attractive as potential prognostic biomarkers. METHODS: The expression of extracellular matrix metalloproteinase inducer (EMMPRIN) was characterised using immunohistochemistry in primary tumours from a cohort of 277 prospectively ... -
Accuracy of Molecular Simulation-Based Predictions of koff Values: A Metadynamics Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-16)The koff values of ligands unbinding to proteins are key parameters for drug discovery. Their predictions based on molecular simulation may under- or overestimate experiment in a system- and/or technique-dependent way. Here we use an established method infrequent metadynamics, based on the AMBER force field to compute the koff of the ligand iperoxo (in clinical use) targeting the muscarinic receptor ... -
Seasonal pollutant levels in littoral high-Arctic amphipods in relation to food sources and terrestrial run-off
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-03)Increasing terrestrial run-off from melting glaciers and thawing permafrost to Arctic coastal areas is expected to facilitate re-mobilization of stored legacy persistent organic pollutants (POPs) and mercury (Hg), potentially increasing exposure to these contaminants for coastal benthic organisms. We quantified chlorinated POPs and Hg concentrations, lipid content and multiple dietary markers, in a ... -
A qualitative study of final-year medical students’ perspectives of general practitioners’ competencies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011-09-23)Objectives: To investigate final-year medical students' perspectives of general practitioners' competencies. A further aim of the study was to investigate which type of clinical problems is properly managed by GPs according to students.<p> <p>Methods: We conducted a qualitative study of 49 final year medical students from two programmes. Reflective writing statements were used to collect data. ... -
Comparison of effectiveness and safety between granules and decoction of Chinese herbal medicine: A systematic review of randomized clinical trials
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-02-09)Background: The clinical use of Chinese herbal medicine granules is gradually increasing. However, there is still no systematic review comparing the effectiveness and safety of granules with the more traditional method of herbal decoctions.<p> <p>Method: A literature search was conducted using China National Knowledge Infrastructure Databases (CNKI), Chinese Science and Technology Periodical ... -
Pastoral herding strategies and governmental management objectives: predation compensation as a risk buffering strategy in the Saami reindeer husbandry
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011-05-12)Previously it has been found that an important risk buffering strategy in the Saami reindeer husbandry in Norway is the accumulation of large herds of reindeer as this increases long-term household viability. Nevertheless, few studies have investigated how official policies, such as economic compensation for livestock losses, can influence pastoral strategies. This study investigated the effect of ... -
Bone-Specific Drugs and Osteonecrosis of Sites Other Than the Jaw: A Nationwide Cohort Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-07)Bone-specific drugs (BSDs) increase the risk of osteonecrosis of the jaw (ONJ), but whether they increase the risk of osteonecrosis at other sites is not known. Two studies, a cohort study and a case–control study, were conducted using registry data on everyone who was residing in Sweden on December 31, 2005, and who was 50 years of age or older at the time (n = 3,523,912). In the cohort study, ... -
Oxidative addition of methyl iodide to [Rh(PhCOCHCOPh)(CO)(P(OCH2)(3)CCH3)]: an experimental and computational study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011-11-24)The reaction rate of the oxidative addition and CO insertion steps of methyl iodide with [Rh(PhCOCHCOPh)(CO)(P(OCH<sub>2</sub> ) <sub>3</sub> CCH<sub>3</sub> )] are presented. Large negative experimental values for the activation entropy and results from a density functional theory computational chemistry study indicated trans addition of the CH<sub>3</sub> I to [Rh(PhCOCHCOPh)(CO)(P(OCH<su ... -
Mapping the Concept, Content, and Outcome of Family-Based Outdoor Therapy for Children and Adolescents with Mental Health Problems: A Scoping Review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-10)Outdoor therapy and family-based therapy are suggested to be promising interventions for the treatment of mental health problems. The aim of the present scoping review was to systematically map the concept, content, and outcome of combining family- and outdoor-based therapy for children and adolescents with mental health problems. The Joanna Briggs Institute methodology and PRISMA guidelines ... -
Alcohol consumption and lower risk of cardiovascular and all-cause mortality: the impact of accounting for familial factors in twins
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-20)Background. A moderate to high alcohol consumption is associated with a lower risk of cardiovascular disease (CVD) mortality in comparison with low consumption. The mechanisms underlying this association are not clear and have been suggested to be caused by residual confounding. The main objective of this study was to separate the familial and individual risk for CVD mortality and all-cause mortality ... -
What should have happened if Hardy had discovered this?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-02-15)First we present and discuss an important proof of Hardy’s inequality via Jensen’s inequality which Hardy and his collaborators did not discover during the 10 years of research until Hardy finally proved his famous inequality in 1925. If Hardy had discovered this proof, it obviously would have changed this prehistory, and in this article the authors argue that this discovery would probably also ... -
U-Pb dating of calcite in ancient carbonates for age estimates of syn-to post-depositional processes: A case study from the upper Ediacaran strata of Finnmark, Arctic Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-10)Results of in situ U–Pb dating of calcite spherulites, cone-in-cone (CIC) calcite and calcite fibres from a calcareous concretion of the upper Ediacaran of Finnmark, Arctic Norway, are reported. Calcite spherulites from the innermost layers of the concretion yielded a lower intercept age of 563 ± 70 Ma, which, although imprecise, is within uncertainty of the age of sedimentation based on fossil ... -
Night-shift work and hematological cancers: A population based case-control study in three Nordic countries
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-11)<b><p>Objective</b> The aim of this case–control study was to assess the effect of night-shift work on the risk of hematological cancers. <b><p>Methods</b> The study included 39 371 leukemia, 56 713 non-Hodgkin lymphoma, 9322 Hodgkin lymphoma, and 26 188 multiple myeloma cases diagnosed between 1961 and 2005 in Finland, Sweden, and Iceland. Five controls for each case were selected from the Nordic ...