Viser treff 1621-1640 av 3251

    • Physical assault in the previous year and total and cause-specific mortality in Russia: A case-control study of men aged 25-54 years 

      Bhavsar, Vishal; Cook, Sarah; Saburova, Lyudmila; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-19)
      Background: Violence has important health effects. The results of exposure to physical violence include, but may not be limited to, death from suicide and homicide. The connection between the experience of assault and risk of death from causes other than homicide and suicide has rarely been examined.<p> <p>Methods: We analysed data from the first Izhevsk Family Study (IFS-1), a populationbased ...
    • A cluster randomized evaluation of an intervention to increase skilled birth attendant utilization in mid- and far-western Nepal. 

      Choulagai, Bishnu P.; Onta, Sharad; Subedi, Narayan; Bhatta, Dharma N.; Shrestha, Binjwala; Petzold, Max; Krettek, Alexandra (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-04)
      killed birth attendant (SBA) utilization is low in remote and rural areas of Nepal. We designed and implemented an evaluation to assess the effectiveness of a five-component intervention that addressed previously identified barriers to SBA services in mid- and far-western Nepal. We randomly and equally allocated 36 village development committees with low SBA utilization among 1-year intervention ...
    • From ark to bank: extinction, proxies and biocapitals in ex-situ biodiversity conservation practices 

      Breithoff, Esther; Harrison, Rodney (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-05)
      This paper takes a critical approach to understanding the social and cultural ‘work’ of natural heritage conservation, focussing specifically on ex-situ biodiversity cryopreservation practices. Drawing on ethnographic fieldwork with the Frozen Ark, a UK-based ‘frozen zoo’ aiming to preserve the DNA of endangered animal species, the paper situates the development of nonhuman animal biobanks in ...
    • Lost relation between blood pressure and serum 25-hydroxyvitamin D 

      Jorde, Rolf; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-26)
      Background: Low serum 25-hydroxyvitamin D (25(OH)D) levels have consistently been associated with hypertension. During the last decades there has been an unexplained reduction in blood pressure (BP) in Western countries. We therefore examined the relation between serum 25(OH)D and BP in the 7th survey of the Tromsø study 2015/2016.<p> <p>Methods: Blood pressure and serum 25(OH)D were measured and ...
    • Reducing geographic inequalities in access times for acute treatment of myocardial infarction in a large country: the example of Russia 

      Timonin, Sergey; Kontsevaya, Anna; McKee, Martin; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-01)
      Background: Russia has the largest area of any country in the world and has one of the highest cardiovascular mortality rates. Over the past decade, the number of facilities able to perform percutaneous coronary interventions (PCIs) has increased substantially. We quantify the extent to which the constraints of geography make equitable access to this effective technology difficult to ...
    • The impact of personality and self-efficacy on academic and military performance: The mediating role of self-efficacy 

      Fosse, Thomas Hol; Buch, Robert; Säfvenbom, Reidar; Martinussen, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-23)
      In order to optimize recruitment and the overall outcome of educational programmes, it is crucial to understand personal determinants of achievement. While several cognitive abilities and skills individually predict performance in academic and professional settings, it is less clear how personality translates into performance. This study addresses the impact of the Big Five personality trait, ...
    • Wavelet-based analogous phase scintillation index for high latitudes 

      Ahmed, Abu Baker E.; Tiwari, Rajesh N.; Strangeways, Hal J.; Dlay, Satnam Singh; Johnsen, Magnar Gullikstad (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-07-14)
      The Global Positioning System (GPS) performance at high latitudes can be severely affected by the ionospheric scintillation due to the presence of small-scale time-varying electron density irregularities. In this paper, an improved analogous phase scintillation index derived using the wavelet-transform-based filtering technique is presented to represent the effects of scintillation regionally at ...
    • A quantitative model for heat pulse propagation across large helical device plasmas 

      Zhu, Hao; Dendy, Richard O.; Chapman, Sandra; Inagaki, Shigeru (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-26)
      It is known that rapid edge cooling of magnetically confined plasmas can trigger heat pulses that propagate rapidly inward. These can result in large excursion, either positive or negative, in the electron temperature at the core. A set of particularly detailed measurements was obtained in Large Helical Device (LHD) plasmas [S. Inagaki et al., Plasma Phys. Controlled Fusion 52, 075002 (2010)], ...
    • Validation of the Graded Prognostic Assessment for Melanoma Using Molecular Markers (Melanoma-molGPA). 

      Nieder, Carsten; Hintz, Mandy; Bilger, Angelika; Oehlke, Oliver; Grosu, Anca L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03)
      Background: It has been suggested to replace the diagnosis-specific graded prognostic assessment (DS-GPA, based on performance status and number of brain metastases) for patients with primary malignant melanoma with the new Melanoma-molGPA. The latter is a more complex assessment, which also includes BRAF mutation status, age and extracranial metastases. To test the performance of the Melanoma-molGPA, ...
    • Rapid Intestinal Uptake and Targeted Delivery to the Liver Endothelium Using Orally Administered Silver Sulfide Quantum Dots. 

      Hunt, Nicholas J; Lockwood, Glen P; Le Couteur, Frank H.; McCourt, Peter Anthony; Singla, Nidhi; Kang, Sun; Burgess, Andrew; Kuncic, Zdenka; Le Couteur, David G; Cogger, Victoria C (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-24)
      Quantum dots (QDs) are used for imaging and transport of therapeutics. Here we demonstrate rapid absorption across the small intestine and targeted delivery of QDs with bound materials to the liver sinusoidal endothelial cells (LSECs) or hepatocytes in vitro and in vivo following oral administration. QDs were radiolabeled with <sup>3</sup> H-oleic acid, with a fluorescent tag or <sup>14</su ...
    • Learning the Sámi language outside of the Sámi core area in Norway 

      Hermansen, Nina; Olsen, Kjell Ole Kjærland (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-20)
      We analyze how the implementation of the Norwegian policy on the Sámi language in school has shaped some Norwegian-speaking Sámi youths’ experiences and challenges of language learning. The research was conducted in Alta, Finnmark county. The youths interviewed in this study have had education in the Sámi language for the larger part, or for the entirety, of their primary and secondary education. ...
    • Zonal Wave Number Diagnosis of Rossby Wave-Like Oscillations Using Paired Ground-Based Radars 

      He, Maosheng; Yamazaki, Yosuke; Hoffmann, Peter; Hall, Chris; Tsutsumi, Masaki; Li, Guozhu; Chau, Jorge L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-03)
      Free traveling Rossby wave normal modes (RNMs) are often investigated through large-scale space-time spectral analyses, which therefore is subject to observational availability, especially in the mesosphere. Ground-based mesospheric observations were broadly used to identify RNMs mostly according to the periods of RNMs without resolving their horizontal scales. The current study diagnoses zonal ...
    • Some new (Hp,Lp) type inequalitiesof maximal operators of Vilenkin-Nörlund means with non-decreasing coefficients 

      Persson, Lars Erik; Tephanadze, G; Wall, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12)
      In this paper we prove and discuss some new (H<sub>p</sub>,L<sub>p</sub>) type inequalities of maximal operators of Vilenkin-Nörlund means with non-decreasing coefficients. We also apply these inequalities to prove strong convergence theorems of such Vilenkin-N ¨orlund means. These inequalities are the best possible in a special sense. As applications, both some well-known and new results are pointed out.
    • Fysisk aktivitet, risikofaktorer for hjerte- og karsykdommer og risiko for tidlig død blant samer og nordmenn i Finnmark 

      Hermansen, Rune Hermann; Jacobsen, Bjarne K. (Chapter; Bokkapittel, 2022-03-16)
      Hjerte- og karsykdommer er en av hovedårsakene til for tidlig død. Fokus på forebyggende tiltak er derfor viktig. Fysisk aktivitet er et gunstig forebyggende tiltak, men det er mangelfull kunnskap om sammenhengen mellom fysisk aktivitet, risikofaktorer for hjerte-og karsykdom og død hos urfolk, som eksempelvis samer. Historisk har den fleretniske befolkningen i nord hatt høyere hjerte- og kardødelighet ...
    • Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling 

      Dodig-Crnković, Tea; Hong, Mun-Gwan; Engel Thomas, Cecilia; Häussler, Ragna S.; Bendes, Annika; Dale, Matilda; Edfors, Fredrik; Forsström, Björn; Magnusson, Patrik K.E.; Schuppe-Koistinen, Ina; Odeberg, Jacob Olof; Fagerberg, Linn; Gummesson, Anders; Bergström, Göran; Mathias, Uhlén; Schwenk, Jochen M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-03)
      Background: Precision medicine approaches aim to tackle diseases on an individual level through molecular profiling. Despite the growing knowledge about diseases and the reported diversity of molecular phenotypes, the descriptions of human health on an individual level have been far less elaborate.<p> <p>Methods: To provide insights into the longitudinal protein signatures of well-being, we ...
    • Circulating prolactin and in situ breast cancer risk in the European EPIC cohort: A case-control study 

      Tikk, Kaja; Sookthai, Disorn; Fortner, Renée T.; Johnson, Theron; Rinaldi, Sabina; Romieu, Isabelle; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Clavel-Chapelon, Françoise; Baglietto, Laura; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Mattiello, Amalia; Agudo, Antonio; Menéndez, Virginia; Sánchez, María-José; Amiano, Pilar; Chirlaque, Maria-Dolores; Barricarte, Aurelio; Bueno-de-Mesquita, H. Bas; Monninkhof, Evelyn M.; Onland-Moret, N. Charlotte; Andresson, Anne; Sund, Malin; Weiderpass, Elisabete; Khaw, Kay-Tee; Key, Timothy J.; Travis, Ruth C.; Merritt, Melissa A.; Riboli, Elio; Dossus, Laure; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-31)
      Introduction: The relationship between circulating prolactin and invasive breast cancer has been investigated previously, but the association between prolactin levels and in situ breast cancer risk has received less attention.<p> <p>Methods: We analysed the relationship between pre-diagnostic prolactin levels and the risk of in situ breast cancer overall, and by menopausal status and use of ...
    • Designing a Service for Compliant Sharing of Sensitive Research Data 

      Sharma, Aakash; Bye Nilsen, Thomas; Johansen, Sivert; Johansen, Dag; Johansen, Håvard D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-09)
      Data-driven research is increasingly becoming fueled by access to open datasets, often shared publicly on the Internet. However, many research projects study sensitive data. They cannot easily participate in this shift as access to their data is significantly controlled by ethical and regulatory constraints. This paper discusses the requirements for building a service that enables sensitive data for ...
    • The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization 

      Zhou, Heng; Forveille, Sabrina; Sauvat, Allan; Sica, Valentina; Izzo, Valentina; Durand, Sylvère; Müller, Kevin; Liu, Peng; Zitvogel, Laurence; Rekdal, Øystein; Kepp, Oliver; Kroemer, Guido (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-10)
      LTX-315 has been developed as an amphipathic cationic peptide that kills cancer cells. Here, we investigated the putative involvement of mitochondria in the cytotoxic action of LTX-315. Subcellular fractionation of LTX-315-treated cells, followed by mass spectrometric quantification, revealed that the agent was enriched in mitochondria. LTX-315 caused an immediate arrest of mitochondrial ...
    • Protein kinase A opposes the phosphorylation-dependent recruitment of glycogen synthase kinase 3β to A-kinase Anchoring Protein 220 

      Whiting, Jennifer L.; Nygren, Patrick J.; Tunquist, Brian J.; Langeberg, Lorene K.; Seternes, Ole Morten; Scott, John D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-18)
      The proximity of an enzyme to its substrate can influence rate and magnitude of catalysis. A-kinase anchoring protein 220 (AKAP220) is a multivalent anchoring protein that can sequester a variety of signal transduction enzymes. These include protein kinase A (PKA) and glycogen synthase kinase 3 (GSK3). Using a combination of molecular and cellular approaches we show that GSK3 phosphorylation of ...
    • Kunstnerisk utviklingsarbeid og satelittvirksomhet 

      Torell, Lisa; Edvine, Larssen (Journal article; Tidsskriftartikkel; Peer reviewed, 2017)
      Kan man ane en viss risiko idet kunstutdanningsinstitusjonene nå overtar ansvaret individuelt for det arbeidet det nasjonale og tverrkunstneriske stipendiatprogrammet for kunstnerisk utviklingsarbeid (PKU), har utført? spør Edvine Larssen og Lisa Torell.