In pregnancy during an inflammatory condition, macrophages present at the feto-maternal junction release an increased amount of nitric oxide (NO) and pro-inflammatory cytokines such as TNF-α and INF-γ, which can disturb the trophoblast functions and pregnancy outcome. Measurement of the cellular and sub-cellular morphological modifications associated with inflammatory responses are important in order ...

Benchtop diffusion nuclear magnetic resonance (NMR) spectroscopy was used to perform quantitative monitoring of enzymatic hydrolysis. The study aimed to test the feasibility of the technology to characterize enzymatic hydrolysis processes in real time. Diffusion ordered spectroscopy (DOSY) was used to measure the signal intensity and apparent self-diffusion constant of solubilized protein in ...

The BCR-ABL T315I mutation causes resistance to imatinib, nilotinib and dasatinib in chronic myeloid leukemia. Forty BCR-ABL positive patients with imatinib resistance were analyzed for T315I mutated clones after six months on nilotinib or dasatinib treatment by quantitative allele-specific ligation polymerase chain reaction with a sensitivity of 0.05%. Ligation polymerase chain reaction revealed ...

From the invention of the atomic force microscope (AFM) in 1986, tremendous efforts have been put into developing this tool. The AFM has long been considered as one of the top choices to probe the nanoscale world with the ability to achieve nanoscale resolution imaging of surfaces under different environments. Advances in instrumentation combined with the exploitation of sophisticated data analysis ...

The mechanical properties of quartz are fundamental to control the plastic behaviour of the continental crust. Our understanding of quartz rheology is still limited in the following respects: i) the large variability of flow law parameters in the earlier literature (stress exponent n = 4 to ≤ 2 and activation energy Q = 120 to 242 kJ/mol), and ii) the difficulty to identify the rate-limiting deformation ...

We study signal processing tasks in which the signal is mapped via some generalized time-frequency transform to a higher dimensional time-frequency space, processed there, and synthesized to an output signal. We show how to approximate such methods using a quasi-Monte Carlo (QMC) approach. We consider cases where the time-frequency representation is redundant, having feature axes in addition to the ...

Glaciogenic reservoirs host important hydrocarbon resources across the globe. Examples such as the Peon and Aviat discoveries in the North Sea show that Quaternary and Neogene reservoirs can be prospective in the region. In this study, we interpret 2D and 3D reflection seismic data combined with borehole information to document unconventional play models from the shallow subsurface of the Norwegian ...

This paper proposes an external sorting algorithm for large data as an alternative to the widely used merge-sort algorithm. The algorithm we present is an application of the widely known quick-sort algorithm to large sequences of data stored externally on a disk device. The problem with the merge-sort algorithm is not its time complexity but the large amount of time it requires to output its first ...

Orbits are an invaluable resource for the global community. However, space pollution is becoming more pronounced as the accumulation of debris continues. Deliberate collisions are a relevant source contributing to this development. When Microsat-R was destroyed with a missile in 2019, it ejected numerous fragments into orbit. Based on observations made with EISCAT UHF, this thesis will investigate ...

Radar Beam-park experiments have been very successful in characterizing the distribution of space debris objects, both in terms of orbital parameters but also in terms of limiting the estimates of their radar cross section, or RCS. A recent paper \[0\] used observed range and range rates to refine orbit estimates by matching up the observed SNR curve to that predicted by simulations. This gives good ...