Diabetes is a complex and time-consuming affair for the people that are afflicted by the disease. A strict self-management regime needs to be followed to avoid short- and long-term complications, which requires a great deal of motivation and support from others. Low- or high-blood glucose levels can cause short- and long-term consequences, ranging from headaches and thirst to coma. In the last few ...

Semi-quantitative estimates of early to late Holocene spring sea ice concentration (SpSIC) andoccurrence of summer sea ice for the northern Barents Sea have been obtained by analysing the biomarkers IP₂₅,brassicasterol and a tri-unsaturated highly branched isoprenoid lipid in a Holocene marine sediment core.Sub-surface water mass variations were derived from planktic foraminiferal assemblages ...

The host-guest chemistry of cryptophanes is an active research area because of its applications in sensor design, targeting small molecules and atoms in environmental and medical sciences. As such, the computational prediction of binding energies and nuclear magnetic resonance (NMR) properties of different cryptophane complexes are of interest to both theoreticians and experimentalists ...

The role played by entropy for the enormous rate enhancement achieved by enzymes has been debated for many decades. There are, for example, several confirmed cases where the activation free energy is reduced by around 10 kcal/mol due to entropic effects, corresponding to a rate enhancement of ∼107 compared to the uncatalyzed reaction. However, despite substantial efforts from both the experimental ...

Speech recognition and communication between humans and machines are increasingly popular today. Several companies already have products in this market segment. The Managed IoT Cloud (MIC) platform is a complete ecosystem for management of Internet of Things (IOT) devices, data storage and analysis of data. However, the platform lacks an integration with a personal assistant to introduces ...

A risk analysis should provide decision makers with information regarding relevant hazards. The initiating phase, where the risk analysts identify hazards to be included in the risk analysis, lays the foundation for the rest of the analysis. This phase is, therefore, of great importance. In this paper, we examine how risk analysts in a municipal setting identified potential adverse events and how ...

The temporal fluctuations in global mean surface temperature are an example of a geophysical quantity that can be described using the notions of long-range persistence and scale invariance/scaling, but this description has suffered from lack of a generally accepted physical explanation. Processes with these statistical signatures can arise from nonlinear effects, for instance, through cascade-like ...

We investigated methane-derived authigenic carbonate (MDAC) crusts and nodules from a cold seep site on the northern Norwegian continental shelf in ca. 220 m water depth to determine the timing and mode of their formation. Gas bubbling observed during remotely operated vehicle (ROV)-assisted sampling of MDAC crusts revealed ongoing seep activity. Authigenic carbonates were present as crusts on the ...

Metal carbenes can undergo a myriad of synthetic transformations. Sulfur ylides are potential safe precursors of metal carbenes. Herein, we report cascade reactions that involve carbenoids derived from sulfoxonium ylides for the efficient and regioselective synthesis of indoles and pyrroles. The tandem action of iridium and Brønsted acid catalysts enables rapid assembly of the heterocycles from ...

Modern vessels are designed to collect, store and communicate large quantities of ship performance and navigation information through complex onboard data handling processes. That data should be transferred to shore based data centers for further analysis and storage. However, the associated transfer cost in large-scale data sets is a major challenge for the shipping industry, today. The same cost ...