<p>Extremophiles, especially those living in high-temperature environments, exhibit unique enzymatic mechanisms that allow survival under conditions detrimental to most life forms. Of particular interest is thermophiles, which are able to thrive at temperatures at which psychrophiles and mesophiles unfold and cease to function. The mechanisms by which these enzymes are able to overcome this temperature ...

Since the discovery of decamethylsilicocene over three decades ago, chemists have successfully isolated a variety of divalent silicon compounds by orchestrating steric and electronic effects to their advantage. Two broad strategies of electronic stabilization appear to have been widely deployed, namely, π-conjugation as in diaminosilylenes and π-complexation as in decamethylsilicocene and ...

The collective effects of sleep loss and sleep disorders are correlated with many adverse health consequences, including increased risk of high blood pressure, obesity, diabetes, depressive state, and cardiovascular symptoms. Research in eHealth can provide methods to enrich personal health care with information and communication technologies (ICTs). An eCoach system may allow people to manage a ...

As meteoroids enter the Earth’s atmosphere, the majority will fully evaporate in the altitude region 70–110 km, due to the frictional heating from atmospheric interactions. The evaporated material is thought to re-condense and coagulate into nanometer sized particles called meteoric smoke particles (MSP). These particles are thought to be a central component in the formation of noctilucent clouds ...

As renewable energy sources offshore wind energy develop quickly, countries like Norway with long coastlines are exploring their potential. However, the diverse wind resources across different regions of Norway present challenges for study for effective utilization of offshore wind energy. This study proposes a novel method that utilizes transfer learning techniques to analyse the resource differences ...

The variability of Arctic sea-ice during abrupt stadial-interstadial shifts in the last glacial period remain poorly understood. Here, we investigated the millennial-scale relationship, with a focus on Heinrich Stadials (HS), between sea-ice cover and bottom water temperature (BWT) during Marine Isotope Stages (MIS) 3 and 2 (64–13 ka) in the Fram Strait using new molecular sea ice biomarker data and ...

Precise ischemic lesion segmentation plays an essential role in improving diagnosis and treatment planning for ischemic stroke, one of the prevalent diseases with the highest mortality rate. While numerous deep neural network approaches have recently been proposed to tackle this problem, these methods require large amounts of annotated regions during training, which can be impractical in the medical ...

Recent advances in sequencing technologies and platforms have enabled to generate metagenomics sequences using different sequencing platforms. In this study, we analyzed and compared shotgun metagenomic sequences generated by HiSeq3000 and BGISEQ-500 platforms from 12 sediment samples collected across the Norwegian coast. Metagenomics DNA sequences were normalized to an equal number of bases for ...

Chorismate mutase (CM) enzymes have long served as model systems for benchmarking new methods and tools in computational chemistry. Despite the enzymes’ prominence in the literature, the extent of the roles that activation enthalpy and entropy play in catalyzing the conversion of chorismate to prephenate is still subject to debate. Knowledge of these parameters is a key piece in fully understanding ...

Because of a spring predictability barrier, the seasonal forecast skill of Arctic summer sea ice is limited by the availability of melt-season sea ice thickness (SIT) observations. The first year-round SIT observations, retrieved from CryoSat-2 from 2011 to 2020, are assimilated into the GFDL ocean–sea ice model. The model's SIT anomaly field is brought into significantly better agreement with the ...