Triage of women with ASC-US/LSIL cytology: The added value of implementation of an HPV-test
AuthorMsomphora, Mbachi Ruth; Sørbye, Sveinung Wergeland; Gutteberg, Tore Jarl; Skjeldestad, Finn Egil
This study has an historical prospective design by including in retrospect all screening- and follow-up tests for women aged 25 to 69 years old kept by the Department of Clinical Pathology, University Hospital of Northern Norway, Tromsø. All women with a first ASC-US/LSIL smear in 1996-98 and 2006-08 were identified and compared on outcomes such as proportion of cases resolved within 35 months of index smear and incidence of CIN2+. The Department of Clinical pathology has used an mRNA test (NorChip PreTect HPV-Proofer) since the autumn of 2005 in secondary cervical cancer screening. In triage of women with ASC-US/LSIL, the HPV mRNA test significantly reduced the time from the first abnormal cytology until biopsy and had predictive values comparable with those of repeat cytology.
PublisherUiT Norges arktiske universitet
UiT The Arctic University of Norway
CitationEurogin Conference, (2013), 03.-06. November
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