• A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer 

      Høye, Eirik; Fromm, Bastian; Böttger, Paul H.M.; Domanska, Diana; Kristensen, Annette Torgunrud; Lund-Andersen, Christin; Abrahamsen, Torveig Weum; Fretland, Åsmund Avdem; Dagenborg, Vegar Johansen; Lorenz, Susanne; Edwin, Bjørn von Gohren; Hovig, Eivind; Flatmark, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-14)
      Although microRNAs (miRNAs) contribute to all hallmarks of cancer, miRNA dysregulation in metastasis remains poorly understood. The aim of this work was to reliably identify miRNAs associated with metastatic progression of colorectal cancer (CRC) using novel and previously published nextgeneration sequencing (NGS) datasets generated from 268 samples of primary (pCRC) and metastatic CRC (mCRC; ...