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dc.contributor.authorNieder, Carsten
dc.contributor.authorPawinski, Adam
dc.contributor.authorDalhaug, Astrid
dc.date.accessioned2014-03-20T15:40:08Z
dc.date.available2014-03-20T15:40:08Z
dc.date.issued2013
dc.description.abstractRecent studies from Italy, Japan and Norway have confirmed previous reports, which found that a large variety of palliative radiotherapy regimens are used for painful bone metastases. Routine use of single fraction treatment might or might not be the preferred institutional approach. It is not entirely clear why inter-physician and interinstitution differences continue to persist despite numerous randomized trials, meta-analyses and guidelines, which recommend against more costly and inconvenient multi-fraction regimens delivering total doses of 30 Gy or more in a large number of clinical scenarios. In the present mini-review we discuss the questions of whether doctors are ignoring evidence-based medicine or whether we need additional studies targeting specifically those patient populations where recent surveys identified inconsistent treatment recommendations, e.g. because of challenging disease extent. We identify open questions and provide research suggestions, which might contribute to making radiation oncology practitioners more confident in selecting the right treatment for the right patient.en
dc.identifier.citationRadiation Oncology 8(2013) nr. 1 s. 85-en
dc.identifier.cristinIDFRIDAID 1025069
dc.identifier.doihttp://dx.doi.org/10.1186/1748-717X-8-85
dc.identifier.issn1748-717X
dc.identifier.urihttps://hdl.handle.net/10037/6025
dc.identifier.urnURN:NBN:no-uit_munin_5720
dc.language.isoengen
dc.publisherBioMed Centralen
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762en
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762en
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Radiology and diagnostic imaging: 763en
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Radiologi og bildediagnostikk: 763en
dc.titleContinous controversy about radiation oncologists' choice of treatment regimens for bone metatases: should we blame doctors, canser-related features, or design of previous clinical studiesen
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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