• A porcine model of hemodialyzer reactions: roles of complement activation and rinsing back of extracorporeal blood 

      Pethő, Ákos; Piecha, Dorothea; Mészáros, Tamás; Urbanics, Rudolf; Moore, Christoph; Canaud, Bernard; Mollnes, Tom Eirik; Steppan, Sonja; Szénási, Gábor; Szebeni, János; Dézsi, László (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-09)
      Hemodialysis reactions (HDRs) resemble complement-activation-related pseudoallergy (CARPA) to certain i.v. drugs, for which pigs provide a sensitive model. On this basis, to better understand the mechanism of human HDRs, we subjected pigs to hemodialysis using polysulfone (FX CorDiax 40, Fresenius) or cellulose triacetate (SureFlux-15UX, Nipro) dialyzers, or Dialysis exchange-set without membranes, ...