• Comparative exoproteome profiling of an invasive and a commensal Staphylococcus haemolyticus isolate 

      Cavanagh, Jorunn Pauline; Pain, Maria Charlene Ronessen; Askarian, Fatemeh; Bruun, Jack-Ansgar; Urbarova, Ilona; Wai, Sun Nyunt; Schmidt, Frank; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-22)
      Staphylococcus haemolyticus is a skin commensal emerging as an opportunistic pathogen. Nosocomial isolates of S. haemolyticus are the most antibiotic resistant members of the coagulase negative staphylococci (CoNS), but information about other S. haemolyticus virulence factors is scarce. Bacterial membrane vesicles (MVs) are one mediator of virulence by enabling secretion and long distance delivery ...
    • Comparative exoproteome profiling of an invasive and a commensal Staphylococcus haemolyticus isolate 

      Cavanagh, Jorunn Pauline; Pain, Maria Charlene Ronessen; Askarian, Fatemeh; Bruun, Jack-Ansgar; Urbarova, Ilona; Wai, Sun Nyunt; Schmidt, Frank; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-22)
      <p><i>Staphylococcus haemolyticus</i> is a skin commensal emerging as an opportunistic pathogen. Nosocomial isolates of <i>S. haemolyticus</i> are the most antibiotic resistant members of the coagulase negative staphylococci (CoNS), but information about other <i>S. haemolyticus</i> virulence factors is scarce. Bacterial membrane vesicles (MVs) are one mediator of virulence by enabling secretion and ...
    • Staphylococcus aureus Membrane-derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models 

      Askarian, Fatemeh; Lapek Jr., John D.; Dongre, Mitesh; Tsai, Chih-Ming; Kumaraswamy, Monika; Kousha, Armin; Valderrama, J. Andrés; Ludviksen, Judith K; Cavanagh, Jorunn Pauline; Uchiyama, Satoshi; Mollnes, Tom Eirik; Gonzalez, David J.; Wai, Sun Nyunt; Victor, Nizet; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-20)
      <i>Staphylococcus aureus</i> produces membrane-derived vesicles (MVs), which share functional properties to outer membrane vesicles. Atomic force microscopy revealed that <i>S. aureus</i>-derived MVs are associated with the bacterial surface or released into the surrounding environment depending on bacterial growth conditions. By using a comparative proteomic approach, a total of 131 and 617 proteins ...