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dc.contributor.authorWinger, Anette
dc.contributor.authorKvarstein, Gunnvald
dc.contributor.authorWyller, Vegard Bruun
dc.contributor.authorSulheim, Dag
dc.contributor.authorFagermoen, Frode Even
dc.contributor.authorSmåstuen, Milada Cvancarova
dc.contributor.authorHelseth, Sølvi
dc.date.accessioned2014-12-16T13:40:55Z
dc.date.available2014-12-16T13:40:55Z
dc.date.issued2014-10-06
dc.description.abstractObjectives<br> Although pain is a significant symptom in chronic fatigue syndrome (CFS), pain is poorly understood in adolescents with CFS. The aim of this study was to explore pain distribution and prevalence, pain intensity and its functional interference in everyday life, as well as pressure pain thresholds (PPT) in adolescents with CFS and compare this with a control group of healthy adolescents (HC).<br> Methods<br> This is a case–control, cross-sectional study on pain including 120 adolescents with CFS and 39 HCs, aged 12–18 years. We measured pain frequency, pain severity and pain interference using self-reporting questionnaires. PPT was measured using pressure algometry. Data were collected from March 2010 until October 2012 as part of the Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial.<br> Results<br> Adolescents with CFS had significantly lower PPTs compared with HCs (p<0.001). The Pain Severity Score and the Pain Interference Score were significantly higher in adolescents with CFS compared with HCs (p<0.001). Almost all adolescents with CFS experienced headache, abdominal pain and/or pain in muscles and joints. Moreover, in all sites, the pain intensity levels were significantly higher than in HCs (p<0.001). Conclusions We found a higher prevalence of severe pain among adolescents with CFS and lowered pain thresholds compared with HCs. The mechanisms, however, are still obscure. Large longitudinal population surveys are warranted measuring pain thresholds prior to the onset of CFS.en
dc.identifier.citationBMJ Open, 2014;4:e005920en
dc.identifier.issn2044-6055
dc.identifier.otherFRIDAID 1185425
dc.identifier.other10.1136/bmjopen-2014-005920
dc.identifier.urihttp://hdl.handle.net/10037/6946
dc.identifier.urnURN:NBN:no-uit_munin_6546
dc.language.isoengen
dc.publisherBMJ Publishing Groupen
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Pediatri: 760en
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Pediatrics: 760en
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en
dc.titlePain and pressure pain thresholds in adolescents With chronic fatigue syndrome and healthy Controls: a cross-sectional studyen
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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