Background: Outpatient parenteral antimicrobial therapy (OPAT) is safe, effective and increasingly available. While OPAT in Norwegian healthcare has been rare, a new continuous ambulatory delivery device (CADD) allowing multiple daily dosing treatments has been innovated making OPAT more accessible.<p> <p>Objectives: To describe the clinical outcome and safety using CADD in an OPAT setting. <p>Methods: ...

We estimate sea-ice type specific incidence angle (IA) dependencies for dual polarized (HH/HV) L and C-band synthetic aperture radar (SAR) for the winter, melt onset and advanced melt seasons for level and deformed ice, using time-series of Advanced Land Observing Satellite-2 (ALOS-2) and Sentinel-1 imagery off the north-east coast of Greenland. The IA dependencies are used to radiometrically ...

BACKGROUND: The lack of standardized reporting for crucial organizational factors in rehabilitation poses a significant barrier to understanding their impact on patient outcomes in clinical trials and meta-analyses. AIM: Based on the categories in the International Classification of Service Organization in Rehabilitation (ICSO-R 2.0), we aimed to develop reporting standards specifically for ...

Purpose - The suicidal process contains both observable and non-observable phases, and patients have described the process as characterized by loneliness and darkness. Ambulance clinicians encounter patients in all phases of the suicidal process but little is known on what meaning this encounter has to the patients. The aim of this study was to elucidate meanings of encountering ambulance clinicians ...

Arctic sea ice mediates atmosphere-ocean momentum transfer, which drives upper ocean circulation. How Arctic Ocean surface stress and velocity respond to sea ice decline and changing winds under global warming is unclear. Here we show that state-of-the-art climate models consistently predict an increase in future (2015–2100) ocean surface stress in response to increased surface wind speed, declining ...

Background - Insertion of an external ventricular drain (EVD) is a first-line treatment of acute hydrocephalus caused by aneurysmal subarachnoid haemorrhage (aSAH). Once the patient is clinically stable, the EVD is either removed or replaced by a permanent internal shunt. The optimal strategy for cessation of the EVD is unknown. Prompt closure carries a risk of acute hydrocephalus or redundant shunt ...

The study aim was to explore how Sámi healthcare staff experience working as an ethnic minority in the Norwegian healthcare system. This was a qualitative focus group and individual interview study inspired by interpretive description, with 14 participants. The results indicate that Sámi healthcare staff experience various degrees of cultural load in their jobs. This was shown through the two themes: ...

En andregangsfødende kvinne i 30-årene ble hemodynamisk ustabil og utviklet sterke brystsmerter etter fødselen. Årsaken til symptomene viste seg å være en alvorlig komplikasjon ved vaginal fødsel etter et tidligere keisersnitt, men omfanget ble ikke avklart før over en uke senere.

Substance-induced psychosis (SIP) is characterized by both substance use and a psychotic state, and it is assumed that the first causes the latter. In ICD-10 the diagnosis is categorized as and grouped together with substance use disorders, and to a large extent also treated as such in the health care system. Though criticism of the diagnostic construct of SIP dates back several decades, numerous ...

Over the past five decades, DNA restriction enzymes have revolutionized biotechnology. While these enzymes are widely used in DNA research and DNA engineering, the emerging field of RNA and mRNA therapeutics requires sequence-specific RNA endoribonucleases. Here, we describe EcoToxN1, a member of the type III toxin-antitoxin family of sequence-specific RNA endoribonucleases, and its use in RNA and ...