Background: Prolactin mirrors the dopaminergic activity in the brain which is key to understanding alcohol use disorders (AUD). Still, patients with AUD are a heterogenous group and there seem to be gender differences in the relationship between alcohol use and the level of prolactin. In this study, we examined gender-wise relationship of alcohol use trait- and state-related factors with the level ...

We developed a simplified, highly efficient Gateway reaction that recombines target DNA to expression (destination) plasmids in vivo and subsequently conjugates the final vector into a recipient strain, all in a single step. This recipient strain does not need to contain any selective marker and can be freely chosen as long as it is sensitive to ccdB counterselection and can be targeted by the RP4α ...

Område for helsetjenester i Folkehelseinstituttet fikk i oppdrag av Barne-, ungdoms- og familiedirektoratet (Bufdir) å identifisere skandinavisk forskning om konsekvenser av covid-19 på velferd, likestilling, livsvilkår og livskvalitet.<p> <p>Metode - Vi utførte en systematisk kunnskapsoppsummering av typen ‘systematisk litteratursøk med sortering’. Vi søkte i mars 2021 i ulike databaser og ...

Fysisk aktivitet i befolkningen skjer i form av bestemte aktiviteter og treningsformer: idretter, mosjonsaktiviteter og friluftsliv. I befolkningen har det vært en markant økning i trenings- og mosjonsaktiviteter de siste 20-årene. Undersøkelser tyder på at den samlede fysiske aktiviteten i befolkningen er under endring. Det er flere som trener og mosjonerer på fritiden, mens hverdagsaktiviteten er ...

Mitochondria are essential energy-providing organelles of particular importance in energy-demanding tissue such as the heart. The production of mitochondria-derived vesicles (MDVs) is a cellular mechanism by which cells ensure a healthy pool of mitochondria. These vesicles are small and fast-moving objects not easily captured by imaging. In this work, we have tested the ability of the optical ...

Data suggest that renal denervation (RDN) in treatment-resistant hypertension (TRHT) is safe in terms of renal function. However, most studies report kidney function as creatinine-based estimated glomerular filtration rate (eGFR), which may be biased by non-renal factors. Damage markers other than albuminuria have never been evaluated after RDN. In this non-randomized RDN trial, we studied changes ...

A detailed, well-dated record of pollen and sedimentary ancient DNA (sedaDNA) for the period 15 000–9500 cal a bp describes changes at Lake Bolshoye Shchuchye in the Polar Ural Mountains, located far east of the classical Lateglacial sites in western Europe. Arctic tundra rapidly changed to lusher vegetation, possibly including both dwarf (Betula nana) and tree birch (B. pubescens), dated in our ...

Purpose - Heat-and-moisture-exchanging devices (HME) are commonly used by endurance athletes during training in sub-zero environments, but their effects on performance are unknown. We investigated the influence of HME usage on running performance at − 15 °C.<p> <p>Methods - Twenty-three healthy adults (15 male, 8 female; age 18–53 years; V˙O_2peak men 56 ± 7, women 50 ± 4 mL·kg<sup>−1 ...

Aquaculture is becoming the primary source of seafood for human diets, and farmed fish aquaculture is one of its fastest growing sectors. The industry currently faces several challenges including infectious and parasitic diseases, reduced viability, fertility reduction, slow growth, escapee fish and environmental pollution. The commercialization of the growth-enhanced AquAdvantage salmon and the ...

This article discusses transnational television and what strategies public service broadcaster NRK Drama has pursued to make the Norwegian crime series Monster: Brutally Far North travel. Monster was the first Norwegian-language television series bought by a major American cable network, Starz. Using the concept of production values, we argue that NRK has made a series that is able to ride the Nordic ...