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Aerobic treatment of selective serotonin reuptake inhibitors in landfill leachate

Permanent lenke
https://hdl.handle.net/10037/8912
DOI
https://doi.org/10.1186/s12302-014-0035-0
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Åpne
article.pdf (520.3Kb)
(PDF)
Dato
2015-01-28
Type
Journal article
Tidsskriftartikkel
Peer reviewed

Forfatter
Bergersen, Ove; Østnes Hanssen, Kine; Vasskog, Terje
Sammendrag
Background: Pharmaceuticals used in human medical care are not completely eliminated in the human body and can enter the municipal sewage sludge system and leachate water from landfill both as the parent compound and as their biologically active metabolites. The selective serotonin reuptake inhibitors (SSRIs) have a large potential for unwanted effects on nontarget organisms in the environment. Leachates from active or old closed landfills are often treated with continuous stirring and simple aeration in a pond/lagoon before infiltration into the environment. The aim of this work was to simulate the reduction of five SSRIs (citalopram, fluoxetine, paroxetine, sertraline and fluvoxamine) and three of their metabolites (desmethylcitalopram, didesmethylcitalopram and norfluoxetine) during aerobic treatment of leachate from landfills. This landfill leachate-simulation experiment was performed to see what happens with the pharmaceuticals during aerated treatment and continuous stirring of landfill leachate for 120 h. It is important to establish whether different pollutants such as pharmaceuticals can be removed (oxidized or otherwise degraded) or not before infiltration into the environment.

Results: All the SSRIs had a significant concentration reduction during the aeration treatment process. Total SSRI concentrations were reduced significantly during aerobic treatment, and the individual SSRIs were reduced by 89% to 100% after 120 h. Among the high-concentration samples, fluoxetine (10 mg L−1) was the least degraded with 93% concentration reduction. Among the low-concentration samples, paroxetine was the least degraded with 89% concentration reduction. Fluvoxamine and citalopram were most effectively eliminated and were completely removed from both the high- and low-concentration samples. The samples were also investigated for the metabolites desmethylcitalopram, didesmethylcitalopram and norfluoxetine but only norfluoxetine in the high-concentration fluoxetine sample was detected.

Conclusions: Our results suggest that aeration is an effective method for eliminating pharmaceuticals such as SSRIs from landfill leachate water. Comparing the results of all SSRIs with different treatment methods, paroxetine and fluvoxamine seem to be the easiest compounds to eliminate independent of method, while fluoxetine and sertraline seem to be the most stable.

Beskrivelse
Published version, also available at http://dx.doi.org/10.1186/s12302-014-0035-0
Forlag
SpringerOpen
Sitering
Environmental Sciences Europe (2015) 27:6
Metadata
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