Aerobic treatment of selective serotonin reuptake inhibitors in landfill leachate
Results: All the SSRIs had a significant concentration reduction during the aeration treatment process. Total SSRI concentrations were reduced significantly during aerobic treatment, and the individual SSRIs were reduced by 89% to 100% after 120 h. Among the high-concentration samples, fluoxetine (10 mg L−1) was the least degraded with 93% concentration reduction. Among the low-concentration samples, paroxetine was the least degraded with 89% concentration reduction. Fluvoxamine and citalopram were most effectively eliminated and were completely removed from both the high- and low-concentration samples. The samples were also investigated for the metabolites desmethylcitalopram, didesmethylcitalopram and norfluoxetine but only norfluoxetine in the high-concentration fluoxetine sample was detected.
Conclusions: Our results suggest that aeration is an effective method for eliminating pharmaceuticals such as SSRIs from landfill leachate water. Comparing the results of all SSRIs with different treatment methods, paroxetine and fluvoxamine seem to be the easiest compounds to eliminate independent of method, while fluoxetine and sertraline seem to be the most stable.