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dc.contributor.authorLicaj, Idlir
dc.contributor.authorLukic, Marko
dc.contributor.authorJareid, Mie
dc.contributor.authorLund, Eiliv
dc.contributor.authorBraaten, Tonje
dc.contributor.authorGram, Inger Torhild
dc.date.accessioned2016-04-11T11:51:18Z
dc.date.available2016-04-11T11:51:18Z
dc.date.issued2016-01-14
dc.description.abstractAmong European women, ovarian cancer is the fifth most common cancer. Smoking is an established risk factor for mucinous tumors. We estimated the impact of smoking in Norwegian women using population attributable fractions (PAFs) of epithelial ovarian cancer (EOC), by invasiveness and by histological subtypes in the Norwegian Women and Cancer Study with an average of 13.2 years of follow-up. During >2 million person-years, a total of 915 incident EOC cases, of which 667 (73%) invasive and 248 (27%) borderline, were identified among 154,234 women aged 34–70 years at enrolment. Compared with never smokers, current smokers had a nonstatistically significant increased risk of mucinous tumors (hazard ratio [HR] = 1.67 [95% confidence interval, (CI), 0.96–2.96]) and more than twice statistically significant risk of borderline mucinous tumors (HR = 2.17 [95% CI, 1.06–4.45]). The corresponding PAF estimates were 16.5% for mucinous and 25% for borderline mucinous. We found that among middle-aged women, one in six mucinous tumors and one in four borderline mucinous tumors could have been prevented if women did not smoke.en_US
dc.descriptionDOI : 10.1002/cam4.590en_US
dc.identifier.citationCancer medicine 2016, 5(4):720-727en_US
dc.identifier.issn2045-7634
dc.identifier.otherFRIDAID 1313854
dc.identifier.other10.1002/cam4.590
dc.identifier.urihttp://hdl.handle.net/10037/9117
dc.identifier.urnURN:NBN:no-uit_munin_8682
dc.language.isoengen_US
dc.publisherJohn Wiley & Sonsen_US
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medical disciplines: 700en_US
dc.titleEpithelial ovarian cancer subtypes attributable to smoking in the Norwegian Women and Cancer Study, 2012en_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelno
dc.typePeer revieweden_US


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