Today's manufacturing landscape is undergoing constant changes, particularly through the widespread integration of advanced digital technologies. Among these, Metal Additive Manufacturing (MAM) stands out, signaling a new era of flexibility and customization capabilities that promise to significantly enhance business competitiveness, sustainability, and cost efficiency. However, the outcomes of MAM ...

Bloodstream infections (BSIs) are a severe public health threat due to their rapid progression into critical conditions like sepsis. This study presents a novel eXplainable Artificial Intelligence (XAI) framework to predict BSIs using historical electronic health records (EHRs). Leveraging a dataset from St. Olavs Hospital in Trondheim, Norway, encompassing 35,591 patients, the framework integrates ...

Diving mammals are perpetually required to manage low-oxygen conditions throughout their lives. The mammalian brain is an organ particularly vulnerable to low oxygen levels due to its high energy demands, which require steady aerobic ATP production. The brain of the deep- diving hooded seal (Cystophora cristata) demonstrates remarkable tolerance to hypoxia. Studies suggest that this brain hypoxia ...

<p><i>Background/aims:</i> Limb-girdle muscular dystrophy R9 (LGMDR9) is a rare autosomal recessive muscle disease caused by mutations in the fukutin-related protein gene, FKRP. The prevalence is higher in northern European populations, where it is closely associated with the FKRP c.826CA allele. This work aims to study the epidemiology of LGMDR9 in Norway, natural history, and relationships with ...

Climate-induced ecotonal shifts are expected to occur in the (sub)arctic and boreal zones in the coming decades. Understanding how these ecosystems have previously responded to climate change can provide greater insight into how ecosystems may develop under existing and future pressures. Here we present a Holocene record from Lake Horntjernet, a lake on the northern edge of the boreal forest in ...

Pots are traditional fishing gear type largely employed in Mediterranean Small Scale Fisheries (SSFs). Their often higher species selectivity and catch quality compared to other gear types such as passive set nets or trawls are appealing characteristics for reducing the impact on benthic communities and diversifying fishing effort in the region. Despite this, in some SSFs, pots are still rarely used ...

Emergency departments (EDs) handle urgent medical needs for a diverse population. Medication errors and adverse drug events pose safety risks in the ED. Clinical pharmacists, experts in medication use, play a crucial role in identifying and optimizing medication therapy. The aim of this study was to investigate how clinical pharmacists introduced into the ED interdisciplinary teams distribute ...

Objectives To evaluate the acute effect of exposure to a potentiation warm-up protocol compared to a usual warm-up program. <p>Design Randomized parallel control trial. <p>Setting Synthetic grass in the club’s facilities (Portugal). Participants Seventeen female football players (age: 23.9±3.9 years), were randomly allocated to a control (n=8) and an experimental group (n=9). To allocate the ...

This dissertation is based on a naturalistic multicentre study in the context of an interdisciplinary assessment in neuropediatric clinics. The main objective was to expand knowledge about this assessment, focusing primarily on the role of screening instruments completed by caregivers and their satisfaction with the assessment. The validity and usefulness of screening tools for parental mental health ...

Tertiary lymphoid structures (TLSs) are formed in tissues targeted by chronic inflammation processes, such as infection and autoimmunity. In Sjögren’s disease, the organization of immune cells into TLS is an important part of disease progression. Here, we investigated the dynamics of tissue resident macrophages in the induction and expansion of salivary gland TLS. We induced Sjögren’s disease by ...