Background - The atherosclerotic effect of an adverse lipid profile is assumed to accumulate throughout life, leading to increased risk of myocardial infarction (MI). Still, little is known about age at onset and duration of unfavorable lipid levels before MI.<p> <p>Methods and Results - Longitudinal data on serum lipid levels for 26 130 individuals (50.5% women, aged 20–89 years) were obtained ...

Aim - To explore the experiences and needs of family members during the course of COVID-19 critical illness from onset to rehabilitation.<p> <p>Design - An exploratory qualitative study.<p> <p>Methods - Twelve family members of surviving critically ill COVID-19 patients and restricted from visiting the patients, were interviewed digitally. Reflexive thematic analysis was used.<p> <p>Results ...

Machine Learning (ML) methods have become important for enhancing the performance of decision-support predictive models. However, class imbalance is one of the main challenges for developing ML models, because it may bias the learning process and the model generalization ability. In this paper, we consider oversampling methods for generating synthetic categorical clinical data aiming to improve the ...

Objective - To evaluate the predictive value of biomarkers of inflammation like phagocyte-related S100 proteins and a panel of inflammatory cytokines in order to differentiate the child with acute lymphoblastic leukemia (ALL) from juvenile idiopathic arthritis (JIA).<p> <p>Study design - In this cross-sectional study, we measured S100A9, S100A12, and 14 cytokines in serum from children with ALL ...

<p>Childhood cancer treatment protocols have been successful due to the prompt and accurate diagnosis, availability of care, and access to high-quality medical resources. As the survival rates increase in high-income countries (HIC), the emphasis has shifted from survival to survival, emphasizing quality of life. The health complaints and adverse effects of cancer treatment are burdensome for children, ...

Let S be a connected non-orientable surface with negative Euler characteristic and of finite type. We describe the possible closures in ML and PML of the mapping class group orbits of measured laminations, projective measured laminations and points in Teichmüller space. In particular we obtain a characterization of the closure in ML of the set of weighted two-sided curves.

We consider cones of real forms which are sums of squares and invariant under a (finite) reflection group. Using the representation theory of these groups we are able to use the symmetry inherent in these cones to give more efficient descriptions. We focus especially on the <i>A</i>_n, <i>B</i>_n and <i>D</i>_n case where we use so-called higher Specht polynomials to ...

Amid the alarming atmospheric and oceanic warming rates taking place in the Arctic, western fjords around the Svalbard archipelago are experiencing an increased frequency of warm water intrusions in recent decades, causing ecological shifts in their ecosystems. However, hardly anything is known about their potential impacts on the until recently considered stable and colder northern fjords. We ...

Rock-derived or petrogenic organic carbon has traditionally been regarded as being non-bioavailable and bypassing the active carbon cycle when eroded. However, it has become apparent that this organic carbon might not be so inert, especially in fjord systems where petrogenic organic carbon influxes can be high, making its degradation another potential source of greenhouse gas emissions. The extent ...

Objectives: To contribute further knowledge about symptoms of anxiety, depression, body concerns, and self-worth among young talent development (TD) and mainstream students by exploring the indicators within-person combinations prospectively, aiming to identify distinct profiles. Methods: We included 946 students, n = 168 (45% girls) from three TD sports schools and one ballet class, n = 778 ...