Munin: Recent submissions

Now showing items 8441-8460 of 36288

    • Italienisch als Herkunftssprache im Fremdsprachen-unterricht: Die Rolle der Dialektkompetenz 

      Arona, Sebastiano; Kupisch, Tanja (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-01)
      Unser Beitrag beschäftigt sich mit italienischen Herkunftssprecher/innen im Fremdsprachenunterricht Italienisch in Baden-Württemberg, wobei wir drei Perspektiven einnehmen: (i) die Mikro-Perspektive der Herkunftssprecher/innen, die in der Regel flüssig Italienisch sprechen, aber oft bidialektal mit einer Varietät des Italienischen sind, (ii) die Meso-Perspektive der Lehrenden, die diese angemessen ...

    • Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood 

      Johnson, Christina; Quach, Huy Quang; Lau, Corinna; Ekholt, Karin; Espevik, Terje; Woodruff, Trent M.; Pischke, Soeren; Mollnes, Tom Eirik; Nilsson, Per (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-15)
      Thrombin plays a central role in thromboinflammatory responses, but its activity is blocked in the common ex vivo human whole blood models, making an ex vivo study of thrombin effects on thromboinflammatory responses unfeasible. In this study, we exploited the anticoagulant peptide Gly-Pro-Arg-Pro (GPRP) that blocks fibrin polymerization to study the effects of thrombin on acute inflammation in ...

    • Management of bleeding risk in patients who receive anticoagulant therapy for venous thromboembolism: Communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease 

      den Exter, Paul L.; Woller, Scott C.; Robert-Ebadi, Helia; Masias, Camila; Morange, Pierre-Emmanuel; Castelli, David; Hansen, John Bjarne; Geersing, Geert-Jan; Siegal, Deborah M.; de Wit, Kerstin; Klok, Frederikus A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-20)
      Patients with acute venous thromboembolism (VTE) require anticoagulant therapy to prevent recurrent VTE and death, which exposes them to an inherent increased risk of bleeding. Identification of patients at high risk of bleeding, and mitigating this risk, is an essential component of the immediate and long-term therapeutic management of VTE. The bleeding risk can be estimated by either implicit ...

    • How to quantify bilingual experience? Findings from a Delphi consensus survey 

      De Cat, Cecile Marie-Rose; Kascelan, Drasko; Serratrice, Ludovica; Tuller, Laurie; Unsworth, Sharon (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-04)
      While most investigations of bilingualism document participants’ language background, there is an absence of consensus on how to quantify bilingualism. The high number of different language background questionnaires used by researchers and practitioners jeopardises data comparability and cross-pollination between research and practice. Using the Delphi consensus survey method, we asked 132 ...

    • Late onset sensory-motor axonal neuropathy, a novel SLC12A6 related phenotype 

      Løseth, Sissel; Høyer, Helle; Delpire, Eric; Kinge, Einar; Lande, Asgeir; Hilmarsen, Hilde Tveitan; Fagerheim, Toril; Nilssen, Øivind; Braathen, Geir Julius; Le, Kim-Mai (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-21)
      We describe five families from different regions in Norway with a late onset autosomal dominant hereditary polyneuropathy sharing a heterozygous variant in the SLC12A6 gene. Mutations in the same gene have previously been described in infants with autosomal recessive hereditary motor and sensory neuropathy with corpus callosum agenesis and mental retardation (Andermann syndrome), and in a few ...

    • Glioblastoma PET/MRI: kinetic investigation of [<sup>18</sup>F]rhPSMA-7.3, [<sup>18</sup>F]FET and [<sup>18</sup>F]fluciclovine in an orthotopic mouse model of cancer 

      Lindemann, Marcel; Oteiza, Ana; Martin-Armas, Montserrat; Guttormsen, Yngve; Moldes-Anaya, Angel; Berzaghi, Rodrigo; Bogsrud, Trond; Bach-Gansmo, Tore; Sundset, Rune; Kranz, Mathias (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-22)
      <b><p>Purpose</b> Glioblastoma multiforme (GBM) is the most common glioma and standard therapies can only slightly prolong the survival. Neo-vascularization is a potential target to image tumor microenvironment, as it defines its brain invasion. We investigate [<sup>18</sup>F]rhPSMA-7.3 with PET/MRI for quantitative imaging of neo-vascularization in GBM bearing mice and human tumor tissue and compare ...

    • Heat extraction capacity and its attenuation of deep borehole heat exchanger array 

      Zhang, Fangfang; Yu, Mingzhi; Sørensen, Bjørn R.; Cui, Ping; Zhang, Wenke; Fang, Zhaohong (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-01)
      A model is proposed to analyze the heat transfer of deep borehole heat exchanger (DBHE)arrays. Based on this, a dimension reduction algorithm is proposed for the numerical simulation of heat transfer of DBHE arrays, which can improve calculation speed by several orders of magnitude compared with that by the CFD software. An index of heat extraction capacity (HECI) is adopted to evaluate the heat ...

    • Can Difficult Lectures be Interesting AND Pleasant? Hedonic and Eudaimonic Feelings as a Function of Perceived Difficulty 

      Ivan, Håvard (Master thesis; Mastergradsoppgave, 2022-12-01)
      What is it that makes challenge and complexity so appealing to humans? Research derived from positive psychology have tried to answer this question, and in the process found evidence suggesting that people experience different feelings as the perception of difficulty rises. In this study, using Gudrun Eckblad’s scheme theory as premise, we predicted that reported feelings of pleasure would be most ...

    • New Building Blocks for Cancer Phototherapeutics: 5d Metallocorroles 

      Einrem, Rune Finsås (Doctoral thesis; Doktorgradsavhandling, 2023-02-24)
      Corroles are ring-contracted, triprotic analogues of porphyrins. This PhD study expands earlier knowledge in particular on ReO corroles. Early on, it became apparent that ReO corroles exhibit the highest phosphorescence quantum yields among all metallocorroles. They also sensitize singlet oxygen formation and serve as oxygen sensors and as triplet-triplet annihilation upconverters. I accordingly ...

    • Visual problems are associated with long-term fatigue after stroke 

      Garder Pedersen, Synne; Løkholm, Mari Thoresen; Friborg, Oddgeir; Halvorsen, Marianne; Kirkevold, Marit; Heiberg, Guri; Anke, Audny (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-30)
      Objective: Post-stroke fatigue may be associated with functioning even in patients with mild stroke. In order to guide rehabilitation, the aim of this study was to investigate the independent contribution of 12 function-related domains to severe long-term fatigue.<p> <p>Design: Observational follow-up study. Subjects: A total of 144 stroke survivors (mean age 67.3, standard deviation (SD) 10.9 ...

    • The effect of machine learning tools for evidence synthesis on resource use and time-to-completion: protocol for a retrospective pilot study 

      Muller, Ashley; Berg, Rigmor; Meneses Echavez, Jose Francisco; Ames, Heather Melanie R; Borge, Tiril Cecilie; Jacobsen Jardim, Patricia Sofia; Cooper, Chris; Rose, Christopher James (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-17)
      Background Machine learning (ML) tools exist that can reduce or replace human activities in repetitive or complex tasks. Yet, ML is underutilized within evidence synthesis, despite the steadily growing rate of primary study publication and the need to periodically update reviews to reflect new evidence. Underutilization may be partially explained by a paucity of evidence on how ML tools can reduce ...

    • The Earldom of Orkney, the Duchy of Schleswig and the Kalmar Union in 1434 

      Grohse, Ian Peter; Magnussen, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-02)
      In August 1434, Erik VII, king of Denmark, Norway and Sweden, confirmed William Sinclair as earl of Orkney, thus ending a decade-long dispute over the hereditary nature of that island fief. Although surviving sources pertaining to Orkney tell us little about Erik VII’s motives, historians have traditionally pointed to circumstances in and around the isles to explain the king’s acknowledgement of ...

    • Testing the Astolfo Effect on newly-released servants in Fate/Grand Order 

      Tomotani, João V.; Salvador, Rodrigo Brincalepe (Journal article; Tidsskriftartikkel; Peer reviewed, 2022)
      Back in 2021, we wrote an article defining the Astolfo Effect. That is what happens when a pop culture representation of a character (fictional or otherwise) becomes more popular than the original. We named it after Astolfo, one of Charlemagne’s paladins and arguably an obscure character in the works that make up the Matter of France and in later literature related to it (such as Orlando ...

    • Changing patterns in treatment, remission status, and categories in a long-term Nordic cohort study of juvenile idiopathic arthritis 

      Glerup, Mia; Arnstad, Ellen Dalen; Rypdal, Veronika; Peltoniemi, Suvi; Aalto, Kristiina; Rygg, Marite; Nielsen, Susan; Fasth, Anders; Berntson, Lillemor; Nordal, Ellen Berit; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-10)
      Objective - To explore sustainability of achieved remission off medication and defined International League of Associations for Rheumatology (ILAR) categories in juvenile idiopathic arthritis (JIA) and describe the trajectory of disease course over time by comparing treatment, disease activity, and ILAR categories from baseline, 8 years, and 18 years after disease onset.<p> <p>Methods - A total ...

    • Body mass index, waist circumference and pre-frailty/frailty: the Tromsø study 1994−2016 

      Uchai, Shreeshti; Andersen, Lene Frost; Hopstock, Laila Arnesdatter; Hjartåker, Anette (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-23)
      Objective This study investigated the association between obesity, assessed using body mass index (BMI) and waist circumference (WC), and pre-frailty/frailty among older adults over 21 years of follow-up. <p>Design Prospective cohort study. <p>Setting Population-based study among communitydwelling adults in Tromsø municipality, Norway. <p>Participants 2340women and 2169 men aged ≥45 years ...

    • Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID‑19 (Bari‑SolidAct): a randomised, double‑blind, placebo‑controlled phase 3 trial 

      Trøseid, Marius; Arribas, José R.; Assoumou, Lambert; Holten, Aleksander Rygh; Poissy, Julien; Terzic, Vida; Mazzaferri, Fulvia; Baño, Jesús Rodríguez; Eustace, Joe; Hites, Maya; Joannidis, Michael; Paiva, José-Artur; Reuter, Jean; Püntmann, Isabel; Patrick-Brown, Thale Dawn; Westerheim, Elin; Nezvalova-Henriksen, Katerina; Beniguel, Lydie; Dahl, Tuva Børresdatter; Bouscambert, Maude; Halanova, Monika; Péterfi, Zoltán; Tsiodras, Sotirios; Rezek, Michael; Briel, Matthias; Ünal, Serhat; Schlegel, Martin; Ader, Florence; Lacombe, Karine; Amdal, Cecilie Delphin; Rodrigues, Serge; Tonby, Kristian; Gaudet, Alexandre; Heggelund, Lars; Mootien, Joy; Johannessen, Asgeir; Møller, Jannicke Horjen; Pollan, Beatriz Diaz; Tveita, Anders Aune; Kildal, Anders Benjamin; Richard, Jean-Christophe; Dalgard, Olav; Simensen, Victoria Charlotte; Baldé, Aliou; de Gastines, Lucie; del Álamo, Marta; Aydin, Burç; Lund-Johansen, Fridtjof; Trabaud, Mary-Anne; Diallo, Alpha; Halvorsen, Bente; Røttingen, John-Arne; Tacconelli, Evelina; Yazdanpanah, Yazdan; Olsen, Inge Christoffer; Costagliola, Dominique; Study Group, EU-SolidAct (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-10)
      Background Baricitinib has shown efcacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifcally on severe/critical COVID, including vaccinated participants.<p> <p>Methods Bari-SolidAct is a phase-3, multicentre, randomised, double-blind, placebo-controlled trial, enrolling participants from June 3, 2021 to March 7, 2022, stopped prematurely for external ...

    • High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism 

      Damoah, Christabel Esi; Snir, Omri; Hindberg, Kristian Dalsbø; Garred, Peter; Ludviksen, Judith K; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Mollnes, Tom Eirik; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-21)
      Background: Experimental studies have shown that the complement activating enzyme MASP-2 (mannose-binding lectin associated serine protease 2) exhibits a thrombin-like activity and that inhibition of MASP-2 protects against thrombosis. In this study, we investigated whether plasma MASP-2 levels were associated with risk of future venous thromboembolism (VTE) and whether genetic variants linked to ...

    • Feedback Effects on Mind Wandering: A Series of Online Experiments 

      Karlsen, Krister (Mastergradsoppgave; Master thesis, 2022-05-01)
      Replicating in-lab experiments online can ensure scientific progress when physical contact is discouraged, like during the covid-19 pandemic. In this thesis, we replicated the results from Boayue et al. (2021) in-lab Mind Wandering (MW) experiment online. The task uses the Finger-Tapping Random Sequence Generation Task, a sustained attention task, equating MW with Task Unrelated Thoughts (TUTs). In ...

    • Birthday Celebrations Social Impact. What Can We Lear From Children’s Experiences? 

      Smeds, Amanda (Mastergradsoppgave; Master thesis, 2022-12-01)
      Children’s birthday celebrations are a social event including different social activities and birthday rituals. As previous research show rituals to enhance cohesion amongst its ritual participants, we assumed in-group and out-group memberships could be established at birthday celebrations between children in an already constituted group. With this study we aim to gain a better understanding of ...

    • The return from underperformance to sustainable world-class level: A case study of a male cross-country skier 

      Talsnes, Rune Kjøsen; Moxners, Einar Flaktveit; Nystad, Trond; Sandbakk, Øyvind Bucher (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-09)
      Purpose: To determine the main factors associated with unexpected underperformance and prospectively describe the holistic process of returning to sustainable world-class level in a male cross-country skier.<p> <p>Methods: Longitudinal training data was retrospectively analyzed across nine seasons (2012-2013 to 2020-2021), and categorized into training forms (endurance, strength, and speed), ...