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Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-21)Structural features of proton-deficient heteroaromatic natural products, such as the breitfussins, can severely complicate their characterization by NMR spectroscopy. For the breitfussins in particular, the constitution of the five-membered oxazole central ring cannot be unequivocally established via conventional NMR methods when the 4′-position is halogenated. The level of difficulty is exacerbated ... -
Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-12)Non‐homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double‐strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J recombination to increase the repertoire of B and T cell receptors. DSBs are also generated during the class switch recombination (CSR) process in mature B lymphocytes, providing ... -
Time trends in the effects of mindfulness-based cognitive therapy for depression: A meta-analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-21)Recent studies suggest that the effects of cognitive therapies for depression show systematic changes over time. A meta‐analysis was conducted to explore the temporal development of the effect of mindfulness‐based cognitive therapy (MBCT) for current depression in studies that used the Beck Depression Inventory (BDI) or the Hamilton Depression Rating Scale (HDRS) as outcome measures. A systematic ... -
Cyberbullying status and mental health in Norwegian adolescents
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)The aim of the present study was to examine how the cyberbullying status (not involved, cyber‐victim only, cyberbully only, cyber‐victim and bully) is related to the mental health of the adolescents when controlled for traditional bullying experience. We also examined the potential moderator sex on the relationship between cyberbullying status and mental health. Univariate analyses of variance were ... -
The 9+ screening test score does not predict injuries in elite floorball players
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-05)We aimed to examine whether the 9+ screening test score could predict injuries in elite floorball players. Eighty‐four elite floorball players participated in the study. At baseline, two physiotherapists assessed the participants using the 9+ screening test. The test score reflects strength, stability, mobility, and functional movement pattern with an emphasis on the lower body and core. Injuries ... -
Recommendations for initial examination, differential diagnosis, and management of concussion and other head injuries in high-level football
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-17)Head injuries can result in substantially different outcomes, ranging from no detectable effect to transient functional impairments to life‐threatening structural lesions. In high‐level international football (soccer) tournaments, on average, one head injury occurs in every third match. Making the diagnosis and determining the severity of a head injury immediately on‐pitch or off‐field is a major ... -
Information concerning ICU patients’ families in the handover— The clinicians’ «game of whispers»: A qualitative study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-16)<i>Aims and objectives</i> - To explore how information concerning ICU patients´ families is included in the ICU clinicians’ daily handover.<p> <p><i>Background</i> - Handover refers to the transfer of information and care responsibility between clinicians. An effective and precise handover are of great importance to ensure quality of care. Although improvements in handovers have received increasing ... -
The necessity and possibilities of playfulness in narrative care with older adults
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-13)For us, narrative care is grounded in pragmatist philosophy and focused on experience. Narrative care is not merely about acknowledging or listening to people's experiences, but draws attention to practical consequences. We conceptualize care itself as an intrinsically narrative endeavour. In this article, we build on Lugones' understanding of playfulness, particularly to her call to remain attentive ... -
A ‘near‐life experience’: lived experiences of spirituality from the perspective of people who have been subject to inpatient psychiatric care
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-24)<i>Aims</i>: To describe lived experiences of spirituality from the perspective of people who have been subject to inpatient psychiatric care and to interpret these experiences from an understanding of health as dialectical.<p> <p><i>Methods</i>: After approval from a regional ethical board,eleven participants were recruited from two organisations for people with mental health problems. Participants ... -
Study of ice accretion on wind turbine blade profiles using thermal infrared imaging
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-08)Atmospheric icing has been recognized as hindrance in proper utilization of good wind resources in cold regions. There is a growing need to better understand the ice accretion physics along wind turbine blades to improve its performance and for optimal design of anti/de-icing system. This article describes a study of ice accretion along wind turbine blade profiles using thermal infrared imaging. Surface ... -
The All Affected Principle, and the Weighting of Votes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-18)In this article we defend the view that, on the All Affected Principle of voting rights, the weight of a person’s vote on a decision should be determined by and only by the degree to which that decision affects her interests, independently of her voting weights on other decisions. Further, we consider two recent alternative proposals for how the All Affected Principle should weight votes, and give ... -
The Master Study in Telemedicine and E-health at the University of Tromsø, Norway, 2005-2018
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020)In this paper we describe the Master Study in Telemedicine and E-health at the University of Tromsø, Norway. The study enrolled its first students in 2005 and was closed in 2018. We describe and discuss the background of the programme, its development and accomplishments and why it was closed. Hopefully, this narrative will be of use to other programmes focusing on e-health. -
Molecular Interactions Stabilizing the Promatrix Metalloprotease-9·Serglycin Heteromer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-12)Previous studies have shown that THP-1 cells produced an SDS-stable and reduction-sensitive complex between proMMP-9 and a chondroitin sulfate proteoglycan (CSPG) core protein. The complex could be reconstituted in vitro using purified serglycin (SG) and proMMP-9 and contained no inter-disulfide bridges. It was suggested that the complex involved both the FnII module and HPX domain of proMMP-9. The ... -
Plan, recruit, retain: a framework for local healthcare organizations to achieve a stable remote rural workforce
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-03)<i>Background</i> - Recruiting and retaining a skilled health workforce is a common challenge for remote and rural communities worldwide, negatively impacting access to services, and in turn peoples’ health. The research literature highlights different factors facilitating or hindering recruitment and retention of healthcare workers to remote and rural areas; however, there are few practical tools ... -
Serum PTH is not a good marker for defining a threshold for vitamin D deficiency
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-01)<i>Objective</i>: In addition to its skeletal effects, vitamin D may also be important for health in general. It is uncertain what level of serum 25-hydroxyvitamin D (25(OH)D), marker of vitamin D status, is sufficient for these effects. With decreasing serum 25(OH)D levels there is an increase in serum PTH. The point at which this occurs has been considered as a threshold for vitamin D sufficiency. ... -
Adam Smith om markedet og om selvet
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-19)Artikkelen fokuserer på hvilken rolle egeninteresse spiller i The Wealth of Nations av Adam Smith. Grunnlaget for diskusjonen vil være et bestemt syn på den vitenskapelige idealiseringen. I henhold til dette synet hevder Smith at aktørene på markedet er motivert av egeninteresse på tross av at han selv vet at dette ikke nødvendigvis er tilfellet. Selv om denne påstanden kan begrunnes pragmatisk, det ... -
Randomised comparison of provisional side branch stenting versus a two-stent strategy for treatment of true coronary bifurcation lesions involving a large side branch: the Nordic-Baltic Bifurcation Study IV
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-19)<i>Background</i> - It is still uncertain whether coronary bifurcations with lesions involving a large side branch (SB) should be treated by stenting the main vessel and provisional stenting of the SB (simple) or by routine two-stent techniques (complex). We aimed to compare clinical outcome after treatment of lesions in large bifurcations by simple or complex stent implantation.<p> <p><i>Methods</i> ... -
Det bør hete St. Olav's University Hospital på engelsk
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-29)I 78 forskningsartikler ble det engelskspråklige navnet for St. Olavs hospital skrevet på 13 ulike måter. Det offisielle navnet ble ikke brukt i det hele tatt. -
Behandlingsrater for ryggkirurgi i Norge og Helse Nord 2014-18
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-23)<i>BAKGRUNN</i> - Formålet med denne studien var å undersøke om behandlingstilbudet innen ryggkirurgi i Helse Nord er i henhold til den vedtatte funksjonsfordelingen mellom sykehusene i regionen, og om det er geografisk variasjon i tilbudet. Vi undersøkte derfor behandlingsrater i Norge og Helse Nord, samt egendekning i Helse Nord, og vurderte aktiviteten i regionen.<p> <p><i>MATERIALE OG METODE</i> ... -
Clinical characterization of Helicobacter pylori infected patients 15 years after unsuccessful eradication
(Journal article; Tidsskriftartikkel, 2020-09-23)<i>Background and aims</i> - Patients that have failed therapy for Helicobacter pylori (H. pylori) infection are incompletely characterized. The aim of this study was to characterize a H. pylori treatment resistant cohort compared to the cohorts of newly diagnosed, earlier eradicated and non-infected.<p> <p><i>Material and methods</i> - Patients were selected from routine referrals to the Endoscopy ...