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Kunnskapsoppsummering og klassifisering av tiltaket: Circle of Security Virginia – Gruppemodellen (COS-VG) (2. utg.)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-02)<i>BAKGRUNN</i> - Circle of Security (COS), eller <i>Trygghetssirkelen</i> på norsk, er en gruppe intervensjoner utviklet for å fremme god tilknytning mellom foreldre og barn. Intervensjonene retter seg primært mot foreldrenes evne til å forstå barnets grunnleggende behov for trygghet, tilhørighet og autonomi slik at barnets trygghetsfølelse og selvforståelse øker. Denne kunnskapsoppsummeringen ... -
Kunnskapsoppsummering og klassifisering av tiltaket: Telemarksmodellen: Vegen blir til mens vi går den sammen (1.utg.)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-01)<i>Bakgrunn</i> - Telemarksmodellen er en kursrekke utviklet for å fremme psykisk helse og forebygge sosiale vansker for barn som har forståelsesvansker i form av en lett psykisk utviklingshemming. Kursene gis når barnet går på mellomtrinnet i barneskole, ungdomstrinnet og i videregående skole. Formen er psykoedukativ hvor en veksler mellom informasjon, råd, veiledning og samtale om et hverdagsliv ... -
Tuberkulose som tegn på virkelighet i Hamsuns Victoria (1898)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-10)I Victoria (1898) av Knut Hamsun dør den kvinnelige hovedpersonen av tuberkulose bare 23 år gammel. Victoria er en av Hamsuns mest kjente romaner, men tuberkulosen som motiv har kun i liten grad påkalt kritikernes interesse. I denne artikkelen vil jeg drøfte hvordan fremstillingen av tuberkulose korresponderer med Hamsuns egen sykdomserfaring, samt med de rådende historiske og kulturelle forestillinger ... -
Northern Genealogies in ‘The Snow Queen’ and Frozen
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-10)H. C. Andersen’s ‘The Snow Queen’ (1844) and its self-professed adaptation Frozen (2013) both maintain a combined focus on origins and development. I approach the two texts as narratives that explain aspects of human life by showing how they came into being – as accounts that, although not primarily historical, are still bound up with genealogical ways of thinking: how, and from what beginnings, do ... -
Den Norden lesen: Erinnerungen, Wahrnehmungen und Bedeutungen im interdisziplinären Dialog
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-10)Unser Beitrag basiert auf der Methode der dramatischen Montage (Klok & Haselmann 2019). In der Begegnung mit zwei autoethnografischen literarischen Quellen, „Die Doktorsfamilie im hohen Norden“ (Gjems Selmer 1905) und „Eine Frau erlebt die Polarnacht“ (Ritter 1938), bewegen wir uns im Zwischenraum zeitlich und disziplinär getrennter Denkwelten. In unserer jeweiligen Rolle als Kulturwissenschaftlerin ... -
Irradiated tumor fibroblasts avoid immune recognition and retain immunosuppressive functions over NK cells
(Journal article; Tidsskriftartikkel, 2021-01-22)Recent studies have demonstrated that radiotherapy is able to induce anti-tumor immune responses in addition to mediating direct cytotoxic effects. Cancer-associated fibroblasts (CAFs) are central constituents of the tumor stroma and participate actively in tumor immunoregulation. However, the capacity of CAFs to influence immune responses in the context of radiotherapy is still poorly understood. ... -
Salmonid Alphavirus Subtype 3 Induces Prolonged Local B Cell Responses in Atlantic Salmon (Salmo salar) After Intraperitoneal Infection
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-10)B cell responses are a crucial part of the adaptive immune response to viral infection. Infection by salmonid alphavirus subtype 3 (SAV3) causes pancreas disease (PD) in Atlantic salmon (<i>Salmo salar</i>) and is a serious concern to the aquaculture industry. In this study, we have used intraperitoneal (IP) infection with SAV3 as a model to characterize local B cell responses in the peritoneal ... -
Decades of Recovery From Sheep Grazing Reveal No Effects on Plant Diversity Patterns Within Icelandic Tundra Landscapes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-26)Tundra plant communities are often shaped by topography. Contrasting wind exposure, slopes of different inclination and landforms of different curvature affect habitat conditions and shape plant diversity patterns. The majority of tundra is also grazed by ungulates, which may alter topographically induced plant diversity patterns, but such effects may depend on the spatial scales of assessments. ... -
Evaluation of the performance of clinical predictors in estimating the probability of pulmonary tuberculosis among smear-negative cases in Northern Ethiopia: A cross-sectional study
(Journal article; Tidsskriftartikkel, 2020-11-03)<i>Objectives</i> - To evaluate the performance of the predictors in estimating the probability of pulmonary tuberculosis (PTB) when all versus only significant variables are combined into a decision model (1) among all clinical suspects and (2) among smear-negative cases based on the results of culture tests.<p> <p><i>Design</i> - A cross-sectional study.<p> <p><i>Setting</i> - Two public ... -
Analysis of medico-social factors for return to work among patients presenting with haematological malignancy (adamantine): Results of a 'pilot study'
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-02)<i>Objective</i> - The aim of this study was to describe return to work determinants in patients with haematological malignancy.<p> <p><i>Results</i> - This medico-social pilot study included patients with haematological malignancy in the <i>département</i> of Calvados, aged 18 to 55 years, diagnosed between 1st January and 31st December 2010 and alive at 1st January 2015. Patients were identified ... -
Vaccination criteria based on factors influencing COVID-19 diffusion and mortality
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-15)SARS-CoV-2 is highly contagious, rapidly turned into a pandemic, and is causing a relevant number of critical to severe life-threatening COVID-19 patients. However, robust statistical studies of a large cohort of patients, potentially useful to implement a vaccination campaign, are rare. We analyzed public data of about 19,000 patients for the period 28 February to 15 May 2020 by several mathematical ... -
Surgeon’s experience and clinical outcome after retropubic tension‐free vaginal tape - A case series
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-27)<i>Introduction</i> - The retropubic tension‐free vaginal tape procedure has been the preferred method for primary surgical treatment of stress and stress‐dominant mixed urinary incontinence in women for more than 20 years. In this study, we assessed associations between surgeon's experience with the primary tension‐free vaginal tape procedure and both perioperative complications and recurrence ... -
Identification and experimental confirmation of novel cGMP efflux inhibitors by virtual ligand screening of vardenafil-analogues
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-28)<i>Background</i> - Clinical studies have reported overexpression of PDE5 and elevation of intracellular cyclic GMP in various types of cancer cells. ABCC5 transports cGMP out of the cells with high affinity. PDE5 inhibitors prevent both cellular metabolism and cGMP efflux by inhibiting ABCC5 as well as PDE5. Increasing intracellular cGMP is hypothesized to promote apoptosis and growth restriction ... -
On the Status of Transfer in Adult Third Language Acquisition of Early Bilinguals
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-04)The study of linguistic transfer—understood here in terms of the copying of previous linguistic representations—seeks to reveal how domain-relevant prior language knowledge impacts the acquisition and development of new mental representations more generally. Studying sequential multilingualism offers a natural laboratory to observe cognitive-economical mechanisms that avoid redundancy in language ... -
The Nordic Sámediggis and the Limits of Indigenous Self-Determination
(Journal article; Tidsskriftartikkel, 2016)<p>From an international perspective, the popularly elected <i>Sámediggis</i> (Sámi Parliaments), established more than two decades ago in the Nordic countries of Finland, Norway and Sweden, represent unique institutional arrangements to enhance and safeguard indigenous peoples’ right to self-determination. In this article the authors compare the legal basis, status, authority and mandate of the ... -
CALCOCO1 acts with VAMP ‐associated proteins to mediate ER ‐phagy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-11)The endoplasmic reticulum (ER) plays important roles in protein synthesis and folding, and calcium storage. The volume of the ER and expression of its resident proteins are increased in response to nutrient stress. ER‐phagy, a selective form of autophagy, is involved in the degradation of the excess components of the ER to restore homeostasis. Six ER‐resident proteins have been identified as ER‐phagy ... -
Photonic-chip assisted correlative light and electron microscopy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-07)Correlative light and electron microscopy (CLEM) unifies the versatility of light microscopy (LM) with the high resolution of electron microscopy (EM), allowing one to zoom into the complex organization of cells. Here, we introduce photonic chip assisted CLEM, enabling multi-modal total internal reflection fluorescence (TIRF) microscopy over large field of view and high precision localization of the ... -
Biomarkers of major bleeding after incident venous thromboembolism
(Doctoral thesis; Doktorgradsavhandling, 2021-03-23)Major bleeding (MB) events are feared and potentially fatal complications of anticoagulant treatment in patients with venous thromboembolism (VTE). Even though several clinical risk factors are associated with MB risk, the predictive power of currently available risk assessment models remain limited for VTE. The aim of this thesis was to identify biomarkers of MB risk during the first year after an ... -
In-Silico Evaluation of Glucose Regulation Using Policy Gradient Reinforcement Learning for Patients with Type 1 Diabetes Mellitus
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-11)In this paper, we test and evaluate policy gradient reinforcement learning for automated blood glucose control in patients with Type 1 Diabetes Mellitus. Recent research has shown that reinforcement learning is a promising approach to accommodate the need for individualized blood glucose level control algorithms. The motivation for using policy gradient algorithms comes from the fact that adaptively ... -
The relation of gender role attitudes with depression and generalised anxiety disorder in two Russian cities
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-08)<i>Background</i> - Reported traditional gender role attitudes (GRAs) have been related to worse mental health in western countries. This study examined the link of GRAs with symptoms of depression and generalised anxiety disorder (GAD) in two Russian cities.<br><br> <i>Methods</i> - We used interview data from the cross-sectional Know Your Heart Study conducted among 5099 adults aged 35-69 in ...
