<i>Objective</i>: To describe experiences among general practitioners (GPs) in Norway regarding horizontal task shifting experiences associated with adverse events that potentially put patient safety at risk.<p> <p><i>Design and contributors</i>: We conducted a qualitative study with data from a retrospective convenience sample of consecutive, already posted comments in a restricted Facebook group ...

Methanol is an attractive alternative non-food feedstock for industrial fermentations that can be used instead of sugar-based raw materials. Here, the thermophilic and methylotrophic bacterium <i>Bacillus methanolicus</i> MGA3 was metabolically engineered to produce the platform chemical (<i>R</i>)-acetoin from methanol at 50 °C. Three different heterologous <i>alsSD/budAB</i> operons, each encoding ...

Arctic tundra active-layer soils are at risk of soil organic carbon (SOC) depletion and degradation upon global climate warming because they are in a stage of relatively early decomposition. Non-growing season (NGS) warming is particularly pronounced, and observed increases of CO₂ emissions during experimentally warmed NGSs give concern for great SOC losses to the atmosphere. Here, we ...

Seasonal neuroendocrine cycles that govern annual changes in reproductive activity, energy metabolism and hair growth are almost ubiquitous in mammals that have evolved at temperate and polar latitudes. Changes in nocturnal melatonin secretion regulating gene expression in the pars tuberalis (PT) of the pituitary stalk are a critical common feature in seasonal mammals. The PT sends signal(s) to the ...

Occupational hazards exist in the processing of seafood both in land-based facilities as well as on board vessels. Recent findings on occupational injury and respiratory health risks among seafood processing workers were presented and discussed at the IFISH5 conference. Particular emphasis was put on the challenges that im/migrant workers encounter, the greater risks onboard factory vessels, especially ...

<i>Background</i> - Cisplatin-based chemotherapy (CBCT) is part of standard treatment of several cancers. In testicular cancer (TC) survivors, an increased risk of developing metabolic syndrome (MetS) is observed. In this epigenome-wide association study, we investigated if CBCT relates to epigenetic changes (DNA methylation) and if epigenetic changes render individuals susceptible for developing ...

Ocean acidification and warming are two main consequences of climate change that can directly affect biological and ecosystem processes in marine habitats. The Arctic Ocean is the region of the world experiencing climate change at the steepest rate compared with other latitudes. Since marine planktonic microorganisms play a key role in the biogeochemical cycles in the ocean it is crucial to ...

Urespa, meaning “to grow together” in the Ainu language, is a social venture founded at Sapporo University in 2010. The Urespa club brings Indigenous Ainu and Wajin (i.e. non-Ainu) students together in a curriculum-based environment to co-learn the Ainu language and Ainu cultural practices. The initiative’s aim is to restory the conventional narrative of Otherness in Japan by creating a transformative ...

Artikkelen undersøker muligheten for å la Nord-Norge og Sápmi være utgangspunktet for poetologiske refleksjoner. Med utgangspunkt i kongrastenmellom skaperkraften i Guds ord og menneskespråket knytter den an til den sere Wittgesteins forestilling om hvordan vi blir språklige. Gjennom en modifisering av visse tolkninger av Wittgenstein argumenterer artikkelen for et nært, men komplekst forhold mellom ...

Abnormal circulation in solid tumors results in hypoxia, which modulates both tumor intrinsic malignant properties as well as anti-tumor immune responses. Given the importance of hypoxia in glioblastoma (GBM) biology and particularly in shaping anti-tumor immunity, we analyzed which immunomodulatory genes are differentially regulated in response to hypoxia in GBM cells. Gene expression analyses ...