• Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes 

      Csengeri, Dora; Sprünker, Ngoc-Anh; Di Castelnuovo, Augusto F; Niiranen, Teemu; Vishram-Nielsen, Julie K.K.; Costanzo, Simona; Soderberg, Stefan; Jensen, Steen M; Vartiainen, Erkki; Donati, Maria Benedetta; Magnussen, Christina; Camen, Stephan; Gianfagna, Francesco; Løchen, Maja-Lisa; Kee, Frank; Kontto, Jukka; Mathiesen, Ellisiv B.; Koenig, Wolfgang; Blankenberg, Stefan; de Gaetano, Giovanni; Jørgensen, Torben; Kuulasmaa, Kari; Zeller, Tanja; Salomaa, Veikko; Iacoviello, Licia; Schnabel, Renate B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-13)
      Aims<p> <p>There is inconsistent evidence on the relation of alcohol intake with incident atrial fibrillation (AF), in particular at lower doses. We assessed the association between alcohol consumption, biomarkers, and incident AF across the spectrum of alcohol intake in European cohorts.<p> <p>Methods and results <p> In a community-based pooled cohort, we followed 107 845 individuals for the ...
    • Alcohol intake and total mortality in 142 960 individuals from the MORGAM Project: a population-based study 

      Di Castelnuovo, Augusto; Costanzo, Simona; Bonaccio, Marialaura; McElduff, Patrick; Salomaa, Veikko; Männistö, Satu; Moitry, Marie; Ferrières, Jean; Dallongeville, Jean; Thorand, Barbara; Brenner, Hermann; Ferrario, Marco; Veronesi, Giovanni; Pettenuzzo, Emanuela; Tamosiunas, Abdonas; Njølstad, Inger; Drygas, Wojciech; Nikitin, Yuri; Söderberg, Stefan; Kee, Frank; Grassi, Guido; Westermann, Dirk; Schrage, Benedikt; Dabboura, Salim; Zeller, Tanja; Kuulasmaa, Kari; Blankenberg, Stefan; Donati, Maria Benedetta; de Gaetano, Giovanni; Iacoviello, Licia (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)
      Aim To test the association of alcohol consumption with total and cause-specific mortality risk. Design Prospective observational multi-centre population-based study. Setting Sixteen cohorts (15 from Europe) in the MOnica Risk, Genetics, Archiving and Monograph (MORGAM) Project. Participants A total of 142 960 individuals (mean age 50 ± 13 years, 53.9% men). Measurements Average alcohol intake by ...
    • Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults 

      Cameron, Adrian J.; Romaniuk, Helena; Orellana, Liliana; Dallongeville, Jean; Dobson, Annette J; Drygas, Wojciech; Ferrario, Marco; Ferrieres, Jean; Giampaoli, Simona; Gianfagna, Francesco; Iacoviello, Licia; Jousilahti, Pekka; Kee, Frank; Moitry, Marie; Niiranen, Teemu J; Pajak, Andrzej; Palmieri, Luigi; Palosaari, Tarja; Mannisto, Satu; Tamosiunas, Abdonas; Thorand, Barbara; Toft, Ulla; Vanuzzo, Diego; Salomaa, Veikko; Veronesi, Giovanni; Wilsgaard, Tom; Kuulasmaa, Kari; Söderberg, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-30)
      Background - Waist circumference and hip circumference are both strongly associated with risk of death; however, their joint association has rarely been investigated.<p> <p>Methods and Results - The MONICA Risk, Genetics, Archiving, and Monograph (MORGAM) Project was conducted in 30 cohorts from 11 countries; 90 487 men and women, aged 30 to 74 years, predominantly white, with no history of ...
    • Risk Factors, Subsequent Disease Onset, and Prognostic Impact of Myocardial Infarction and Atrial Fibrillation 

      Camen, Stephan; Csengeri, Dora; Geelhoed, Bastiaan; Niiranen, Teemu; Gianfagna, Francesco; Vishram-Nielsen, Julie K.; Costanzo, Simona; Söderberg, Stefan; Vartiainen, Erkki; Börschel, Christin S.; Donati, Maria Benedetta; Løchen, Maja-Lisa; Ojeda, Francisco M.; Kontto, Jukka; Mathiesen, Ellisiv B.; Jensen, Steen; Koenig, Wolfgang; Kee, Frank; de Gaetano, Giovanni; Zeller, Tanja; Jørgensen, Torben; Tunstall-Pedoe, Hugh; Blankenberg, Stefan; Kuulasmaa, Kari; Linneberg, Allan; Salomaa, Veikko; Iacoviello, Licia; Schnabel, Renate B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-24)
      BACKGROUND: Although myocardial infarction (MI) and atrial fibrillation (AF) are frequent comorbidities and share common cardiovascular risk factors, the direction and strength of the association of the risk factors with disease onset, subsequent disease incidence, and mortality are not completely understood.<p> <p>METHODS AND RESULTS: In pooled multivariable Cox regression analyses, we examined ...
    • Risk prediction of atrial fibrillation and its complications in the community using hs troponin I 

      Börschel, Christin S.; Geelhoed, Bastiaan; Niiranen, Teemu; Camen, Stephan; Donati, Maria Benedetta; Havulinna, Aki S.; Gianfagna, Francesco; Palosaari, Tarja; Jousilahti, Pekka; Kontto, Jukka; Vartiainen, Erkki; Ojeda, Francisco M.; den Ruijter, Hester M.; Costanzo, Simona; de Gaetano, Giovanni; Di Castelnuovo, Augusto; Linneberg, Allan; Vishram-Nielsen, Julie K.; Løchen, Maja-Lisa; Koenig, Wolfgang; Jørgensen, Torben; Kuulasmaa, Kari; Blankenberg, Stefan; Iacoviello, Licia; Zeller, Tanja; Söderberg, Stefan; Salomaa, Veikko; Schnabel, Renate B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-05)
      Aims - Atrial fibrillation (AF) is becoming increasingly common. Traditional cardiovascular risk factors (CVRF) do not explain all AF cases. Blood-based biomarkers reflecting cardiac injury such as high-sensitivity troponin I (hsTnI) may help close this gap.<p> <p>Methods - We investigated the predictive ability of hsTnI for incident AF in 45,298 participants (median age 51.4 years, 45.0% men) ...