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dc.contributor.advisorHansen, Terkel
dc.contributor.advisorØdegaard-Jensen, Else Mari
dc.contributor.authorKoveland, Anne Christine
dc.date.accessioned2018-03-15T09:11:10Z
dc.date.available2018-03-15T09:11:10Z
dc.date.issued2017-05-15
dc.description.abstractAnalgesic admixtures are given subcutaneously using patient-controlled analgesia devices and are often used in palliative care. The admixtures contain in most cases several compounds to treat multiple conditions. Despite the wide use, there are few data on the physical and chemical stability of the different admixtures. In this preliminary study, we investigated the stability and compatibility of common compounds in singular and binary admixtures diluted in 0.9 % NaCl: morphine, oxycodone, hydromorphone, midazolam and haloperidol in low and high concentrations. All admixtures were prepared aseptically, and the assays were done with HPLC-UV.en_US
dc.identifier.urihttps://hdl.handle.net/10037/12338
dc.language.isoengen_US
dc.publisherUiT Norges arktiske universiteten_US
dc.publisherUiT The Arctic University of Norwayen_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2017 The Author(s)
dc.subject.courseIDFAR-3911
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Kjemi: 440::Legemiddelkjemi: 448en_US
dc.subjectVDP::Mathematics and natural science: 400::Chemistry: 440::Pharmaceutical chemistry: 448en_US
dc.titleStability of analgesic admixtures. Degradation and compatibility of common compounds in singular and binary admixtures in use for palliative treatmenten_US
dc.typeMaster thesisen_US
dc.typeMastergradsoppgaveen_US


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