• Allochrony as a potential driver for reproductive isolation in adaptive radiations of European whitefish ecomorphs 

      Bitz-Thorsen, Julie; Häkli, Katja; Bhat, Shripathi; Præbel, Kim (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-29)
      In northern Fennoscandian lakes, monophylogenetic lineages of postglacial fishes are radiating into several adaptive forms, but the speciation process is still at an incipient stage. The speciation process has received increased attention over the years, but the underlying mechanisms and drivers are still debated and poorly understood. European whitefish (<i>Coregonus lavaretus</i> [L.]) is the most ...
    • Alt på land 

      Svorken, Marianne; Høgstad, Maria Alfredsen; Esaiassen, Margrethe; Nøstvold, Bjørg Helen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-31)
      Mye av restråstoffet som oppstår om bord på norske torsketrålere blir ikke ført til land. I denne artik-kelen drøfter vi hvorfor fartøy i akkurat denne gruppen ikke utnytter restråstoffet bedre. Gjennom en kvalitativ tilnærming supplert med tallanalyser fra landingsstatistikken diskuteres mulige forklarings-variabler og løsninger. Våre resultater viser at ivaretakelse av restråstoff forbindes med ...
    • Alternative bait trials in the Barents Sea snow crab fishery 

      Araya-Schmidt, Tomas; Olsen, Leonore; Rindahl, Lasse; Larsen, Roger B.; Winger, Paul D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-13)
      Commercial harvesting of snow crab (<i>Chionoecetes opilio</i>) in the Barents Sea started in 2012 by Norwegian fishing vessels. This new fishery has significant bait requirements, representing an emerging conservation challenge. In this study, we evaluate the performance of five alternative (natural) baits manufactured from the waste stream of existing and sustainably managed harp seal (<i>Pagophilus ...
    • Alternative materialer til plast brukt i snurrevadtau og trålmatter 

      Alvestad, Anja Helene; Grimaldo, Eduardo; Lilleng, Grethe; Syversen, Tore; Vollstad, Jørgen; Johnsen, Hilde Rødås (Research report; Forskningsrapport, 2023-10-30)
      Dette prosjektet studerte ulike løsninger for å redusere effekten av slitasje fra fossilbasert, ikke-nedbrytbare plastmaterialer som brukes i snurrevad og trålmatter. Prosjektet testet ulike natur-, syntetiske og biologisk nedbrytbare materialer i laboratorium og i felt. Prosjektet kvantifiserte og sannsynliggjorde hvor mye reduksjon i utslipp ulike tiltak og løsninger kan bidra med. Det inkluderes ...
    • Alternative Rope Materials in Towed Fishing Gear to Reduce Plastic Waste, A Comparative Study of Mechanical Properties and Tolerance Against Wear and Tear 

      Føre, Heidi Moe; Hatlebrekke, Hanne Hjelle; Grimaldo, Eduardo (Chapter; Bokkapittel, 2023-06)
      This paper presents a comparative study assessing the wear tolerance of rope materials in demersal fisheries, specifically seine ropes and dolly ropes. Fourteen different rope materials were assessed in this study, including conventional and alternative commercially available synthetic polymers, and biodegradable materials including natural fibre ropes and custom-made polyester monofilaments. The ...
    • Analysis of bacterial diversity in the intestine of grass carp (Ctenopharyngodon idellus) based on 16S rDNA gene sequences 

      Han, A; Ringø, Einar; Liu, Yuchan; Zhou, Zhigang; He, Suxu; Cao, Yanan; Bin, Yao (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
    • Analysis of the Atlantic salmon genome reveals a cluster of Mx genes that respond more strongly to IFN gamma than to type I IFN 

      Robertsen, Børre; Greiner-Tollersrud, Linn; Jørgensen, Lars Gaute (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-06)
      Mx proteins are antiviral GTPases, which are induced by type I IFN and virus infection. Analysis of the Atlantic salmon genome revealed the presence of 9 Mx genes localized to three chromosomes. A cluster of three Mx genes (SsaMx1 – SsaMx3), which includes previously cloned Mx genes, is present on chromosome (Chr) 12. A cluster of five Mx genes (SsaMx4-SsaMx8) is present on Chr25 while one Mx gene ...
    • Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) 

      Seternes, Tore; Poppe, Trygve T; Bøgwald, Jarl; Lynghammar, Arve; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-28)
      The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and acetate. All animal phyla possess SECs, but the tissue localization of SECs has only been investigated ...
    • “And if you gaze long into an abyss, the abyss gazes also into thee ”: four morphs of Arctic charr adapting to a depth gradient in Lake Tinnsjøen 

      Østbye, Kjartan; Hassve, Marius Hagen; Tamayo, Ana-Maria Peris; Hagenlund, Mari; Vogler, Thomas; Præbel, Kim (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-24)
      The origin of species is a central topic in biology. Ecological speciation might be a driver in adaptive radiation, providing a framework for understanding mechanisms, level, and rate of diversification. The Arctic charr <i>Salvelinus alpinus</i> L. is a polymorphic species with huge morphological and life‐history diversity in Holarctic water systems. We studied adaptive radiation of Arctic charr ...
    • Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp. 

      Schneider, Yannik Karl-Heinz; Østnes Hansen, Kine; Isaksson, Johan; Ullsten-Wahlund, Sara Maria; Hansen, Espen; Andersen, Jeanette Hammer (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-05)
      Two bacterial isolates from the Barents Sea, both belonging to the genus <i>Algibacter</i>, were found to yield extracts with anti-bacterial bioactivity. Mass spectrometry guided dereplication and purification of the active extracts lead to the isolation of the same active principle in both extracts. The structure of the bioactive compound was identified via mass spectrometry and nuclear resonance ...
    • Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress 

      Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh; Røst, Lisa Marie; Misund, Kristine; Andreassen, Trygve; Melø, Torun Margareta; Bartosova, Zdenka; Bruheim, Per; Otterlei, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-05)
      The use of garlic and garlic-based extracts has been linked to decreased incidence of cancer in epidemiological studies. Here we examine the molecular and cellular activities of a simple homemade ethanol-based garlic extract (GE). We show that GE inhibits growth of several different cancer cells in vitro, as well as cancer growth in vivo in a syngeneic orthotopic breast cancer model. Multiple myeloma ...
    • Anti-infectious and anti-inflammatory effects of peptide fragments sequentially derived from the antimicrobial peptide centrocin 1 isolated from the green sea urchin, Strongylocentrotus droebachiensis 

      Bjørn, Camilla; Håkansson, Joakim; Myhrman, Emma; Sjøstrand, Veronika; Haug, Tor; Lindgren, Kerstin; Blencke, Hans-Matti; Stensvåg, Klara; Mahlapuu, Margit (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Bacterial resistance against antibiotic treatment has become a major threat to public health. Antimicrobial peptides (AMPs) have emerged as promising alternative agents for treatment of infectious diseases. This study characterizes novel synthetic peptides sequentially derived from the AMP centrocin 1, isolated from the green sea urchin, for their applicability as anti-infective agents.The microbicidal ...
    • Anti-Infective Effect of Adhesive Probiotic Lactobacillus in Fish is Correlated with Their Spatial Distribution in the Intestinal Tissue 

      He, Suxu; Ran, Chao; Qin, Chubin; Li, Shuning; Zhang, Hongling; de Vos, Willem M.; Ringø, Einar; Zhou, Zhigang (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-16)
      In this study, we tested the distribution of 49 Lactobacillus strains in the mucus and mucosa of the intestine tissue of zebrafish. We observed a progressive change in the spatial distribution of Lactobacillus strains, and suggested a division of the strains into three classes: mucus type (>70% in mucus), mucosa type (>70% in mucosa) and hybrid type (others). The hybrid type strains were more efficient ...
    • Anti-microbial activity and immunomodulation of recombinant hepcidin 2 and NK-lysin from flounder (Paralichthys olivaceus) 

      Li, Xinyu; Chi, Heng; Dalmo, Roy Ambli; Tang, Xiaoqian; Xing, Jing; Sheng, Xiuzhen; Zhan, Wenbin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-21)
      Infections due to pathogens impact global aquaculture economy, where diseases caused by bacteria should be in particular focus due to antibiotic resistance. Hepcidin and NK-lysin are important innate immune factors having potential to be exploited as alternatives to antibiotics due to their antimicrobial activity and immunomodulatory capacity. In this study, the recombinant proteins of hepcidin 2 ...
    • Antigen dose and humoral immune response correspond with protection for inactivated infectious pancreatic necrosis virus vaccines in Atlantic salmon (Salmo salar L) 

      Munang'andu, Hetron Mweemba; Fredriksen, Børge Nilsen; Mutoloki, Stephen; Dalmo, Roy Ambli; Evensen, Øystein (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      An enduring challenge in the vaccinology of infectious pancreatic necrosis virus (IPNV) is the lack of correlation between neutralizing antibodies and protection against mortality. To better understand the immunological basis of vaccine protection, an efficacy trial including Atlantic salmon (Salmo salar L.) vaccinated with a high antigen (HiAg) or low antigen (LoAg) dose vaccine was carried out ...
    • Antimicrobial Activity of Securamines From the Bryozoan Securiflustra securifrons 

      Østnes Hansen, Kine; Hansen, Ida Kristine Østnes; Richard, Céline Sarah Marine; Jenssen, Marte; Andersen, Jeanette Hammer; Hansen, Espen Holst (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-21)
      Natural products and their derivatives have served as powerful therapeutics against pathogenic microorganisms and are the mainstay of our currently available treatment options to combat infections. As part of our ongoing search for antimicrobial natural products from marine organisms, one fraction prepared from the Arctic marine bryozoan <i>Securiflustra securifrons</i> was found to be active against ...
    • Antimicrobial activity of small synthetic peptides based on the marine peptide turgencin A: Prediction of antimicrobial peptide sequences in a natural peptide and strategy for optimization of potency 

      Hansen, Ida Kristine Østnes; Lövdahl, Tomas; Simonovic, Danijela; Østnes Hansen, Kine; Andersen, Aaron John Christian; Devold, hege; Richard, Céline Sarah Marine; Andersen, Jeanette Hammer; Strøm, Morten B.; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-30)
      Turgencin A, a potent antimicrobial peptide isolated from the Arctic sea squirt <i>Synoicum turgens</i>, consists of 36 amino acid residues and three disulfide bridges, making it challenging to synthesize. The aim of the present study was to develop a truncated peptide with an antimicrobial drug lead potential based on turgencin A. The experiments consisted of: (1) sequence analysis and prediction ...
    • The antimicrobial effect of CEN1HC-Br against Propionibacterium acnes and its therapeutic and anti-inflammatory effects on acne vulgaris 

      Han, Rui; Blencke, Hans-Matti; Cheng, Hao; Li, Chun (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-03)
      Propionibacterium acnes is a commensal bacterium, which is involved in acne inflammation. An antimicrobial peptide named CEN1HC-Br, which was isolated and characterized form the green sea urchin, has been shown to possess broad-spectrum antibacterial activity. Little is known concerning the potential effects of its antibacterial and anti-inflammatory properties against P. acnes. To examine the potency ...
    • Antimicrobial peptides in echinoderm host defense 

      Li, Chun; Blencke, Hans-Matti; Haug, Tor; Stensvåg, Klara (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-06)
      Antimicrobial peptides (AMPs) are important effector molecules in innate immunity. Here we briefly summarize characteristic traits of AMPs and their mechanisms of antimicrobial activity. Echinoderms live in a microbe-rich marine environment and are known to express a wide range of AMPs. We address two novel AMP families from coelomocytes of sea urchins: cysteine-rich AMPs (strongylocins) and ...
    • Antimicrobial Peptides in Echinoderms 

      Li, Chun; Haug, Tor; Stensvåg, Klara (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)