Now showing items 81-100 of 930

    • Homing of Antigen-Presenting Cells in Head Kidney and Spleen – Salmon Head Kidney Hosts Diverse APC Types 

      Iliev, Dimitri Borisov; Thim, Hanna Leena; Lagos, Leidy; Olsen, randi; Jørgensen, Jorunn B (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Lymph nodes and spleen are major organs where mammalian antigen-presenting cells (APCs) initiate and orchestrate Ag-specific immune responses. Unlike mammals, teleosts lack lymph nodes and an interesting question is whether alternative organs may serve as sites for antigen presentation in teleosts. In the current study, fluorescent ovalbumin (Ova) and CpG oligonucleotides (ODNs) injected intra-abdominally ...
    • Cellular Antioxidant Effect of Four Bromophenols from the Red Algae, Vertebrata lanosa 

      Olsen, Elisabeth Klungerbo; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Three known bromophenols, 2,3-dibromo-4,5-dihydroxybenzylaldehyde (1), 2,2′,3-tribromo-3′,4,4′,5-tetrahydroxy 6′-hydroxymethyldiphenylmethane (2) and bis(2, 3-dibromo-4,5-dihydroxylbenzyl) ether (3), and one new one, 5,5″-oxybis(methylene)bis (3-bromo-4-(2′,3′-dibromo-4′,5′-dihydroxylbenzyl)benzene-1,2-diol) (4), were isolated from an extract of the red alga, Vertebrata lanosa. The antioxidant ...
    • Antioxidant and Anti-Inflammatory Activities of Barettin 

      Lind, Karianne Fredenfeldt; Hansen, Espen; Østerud, Bjarne; Eilertsen, Karl-Erik; Bayer, Annette; Engqvist, Stig Olov Magnus; Leszczak, Kinga; Jørgensen, Trond Ø.; Andersen, Jeanette hammer (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      In this paper, we present novel bioactivity for barettin isolated from the marine sponge Geodia barretti. We found that barettin showed strong antioxidant activity in biochemical assays as well as in a lipid peroxidation cell assay. A de-brominated synthetic analogue of barettin did not show the same activity in the antioxidant cell assay, indicating that bromine is important for cellular activity. ...
    • Quality of obstetric care in the sparsely populated sub-arctic area of Norway 2009-2011 

      Norum, Jan; Heyd, Anca Kriemhilde; Hjelseth, Bente; Svee, Tove Elisabeth; Mürer, Fred A; Erlandsen, Randi; Vonen, Barthold (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: It is challenging to obtain high quality obstetric care in a sparsely populated area. In the subarctic region of Norway, significant distances, weather conditions and seasonable darkness have called for a decentralized care model. We aimed to explore the quality of this care. Methods: A retrospective study employing data (2009–11) from the Medical Birth Registry of Norway was initiated. ...
    • Pushed or pulled? Understanding fishery exit in a welfare society context 

      Johnsen, Jahn Petter; Vik, Jostein (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      For a long time the number of fishers in Norway has declined. Is the decline the result of an increasingly difficult situation for Norwegian fishers or can other factors have had an impact? Or in other words: are fishers pushed out or pulled out of the fisheries? Our analyses are based on a survey among retired fishers and suggest several reasons for exit: in addition to structural push and pull ...
    • Size selectivity of redfish (Sebastes spp.) in the Northeast Atlantic using grid-based selection systems for trawls 

      Herrmann, Bent; Sistiaga, Manu Berrondo; Larsen, Roger B.; Nielsen, Kåre Nolde (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Using experimental data and a model to predict size selection based on morphological data, we investigated size selection of redfish (Sebastes spp.) in the grid-based selection systems used in Northeast Atlantic trawls. We found that not all redfish make physical contact with the spacing between the bars in the sorting grids while they pass in the direction of the codend, and therefore the ...
    • Antigen dose and humoral immune response correspond with protection for inactivated infectious pancreatic necrosis virus vaccines in Atlantic salmon (Salmo salar L) 

      Munang'andu, Hetron Mweemba; Fredriksen, Børge Nilsen; Mutoloki, Stephen; Dalmo, Roy Ambli; Evensen, Øystein (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      An enduring challenge in the vaccinology of infectious pancreatic necrosis virus (IPNV) is the lack of correlation between neutralizing antibodies and protection against mortality. To better understand the immunological basis of vaccine protection, an efficacy trial including Atlantic salmon (Salmo salar L.) vaccinated with a high antigen (HiAg) or low antigen (LoAg) dose vaccine was carried out ...
    • Et delt mediemarked: Prosesser som fremmer små aviser 

      Holand, Astrid Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Nord-Norge, Europas nordlige utkant, er en region kjennetegnet ved store avstander og spredt befolkning. Her ser det ut til at flere forhold sammen fremmer et desentralisert og superlokalt mediemarked. Økonomiske, politiske, teknologiske og sosiale faktorer peker i samme retning: Isteden for avisdød, ser vi mange nye småaviser. Spørsmålet blir da om denne «grasrotprosessen» er et svar på utfordringer ...
    • Hurtig metode for å estimere buksprenging i pelagisk fisk ombord 

      Slizyte, Rasa; Mozuraityte, Revilija; Martinez, Iciar (Research report; Forskningsrapport, 2013)
      Buksprenging er en kvalitetsforringende prosess hvor bukområdet hos fisken brytes ned post mortem. Denne rapporten oppsummerer arbeidet med utviklingen av en anvendelig hurtigtest for å estimere enzymlekkasje som forårsaker buksprenging i pelagiske fiskearter. Måleutstyret er kommersielt tilgjengelig og krever lite opplæring før bruk. Metoden er brukervennlig og gir en objektiv vurdering av ...
    • CpG oligonucleotides bind TLR9 and RRM-Containing proteins in Atlantic Salmon (Salmo salar) 

      Iliev, Dimitar Borisov; SkjÆveland, ingrid; Jørgensen, Jorunn B (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Bacterial DNA is well-known for its potent immunostimulatory properties which have been attributed to the abundance of CpG dinucleotides within the genomes of prokaryotes. Research has found that mammalian TLR9 is a receptor which mediates the immune response to CpG DNA; however, its functional properties in non-mammalian vertebrates are still poorly characterized. Leukocytes isolated ...
    • Stakeholder Influence and Optimal Regulations: A Common-Agency Analysis of Ecosystem-Based Fisheries Regulations 

      Aanesen, Margrethe; Armstrong, Claire W. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      One aspect of ecosystem-based management is to include new stakeholders. When an environmental NGO (ENGO) gets a say in the fisheries management, this will affect the authorities' optimal regulation. Combining a principal-agent model and a steady-state bioeconomic model, we show that under symmetric information the authorities will moderate their use of regulation as a response to the ENGO's increased ...
    • Transgene and immune gene expression following intramuscular injection of Atlantic salmon (Salmo salar L.) with DNA-releasing PLGA nano- and microparticles 

      Hølvold, Linn Benjaminsen; Fredriksen, Børge Nilsen; Bøgwald, Jarl; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      The use of poly-(D,L-lactic-co-glycolic) acid (PLGA) particles as carriers for DNA delivery has received considerable attention in mammalian studies. DNA vaccination of fish has been shown to elicit durable transgene expression, but no reports exist on intramuscular administration of PLGA-encapsulated plasmid DNA (pDNA). We injected Atlantic salmon (Salmo salar L.) intramuscularly with a plasmid ...
    • Sequence Analysis of the Genome of Piscine Orthoreovirus (PRV) Associated with Heart and Skeletal Muscle Inflammation (HSMI) in Atlantic Salmon (Salmo salar) 

      Markussen, Turhan; Dahle, Maria Krudtaa; Tengs, Torstein; Løvoll, Marie Therese; Finstad, Øystein Wessel; Wiik-Nielsen, Christer R.; Grove, Søren; Lauksund, Reidunn Silje; Robertsen, Børre; Rimstad, Espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Piscine orthoreovirus (PRV) is associated with heart- and skeletal muscle inflammation (HSMI) of farmed Atlantic salmon (Salmo salar). We have performed detailed sequence analysis of the PRV genome with focus on putative encoded proteins, compared with prototype strains from mammalian (MRV T3D)- and avian orthoreoviruses (ARV-138), and aquareovirus (GCRV-873). Amino acid identities were low for ...
    • "Volstadsaken: Den «Høist Ærverdige Ret" 

      Ørebech, Peter (Chronicle; Kronikk, 2013)
      Det uklarhet mht. hva som egentlig er avgjort ved Volstad-dommen (Høyesteretts plenumsdom av 23 oktober 2013). Jeg skal i denne kronikk kort redegjøre for hva som er avgjort og hva dommen ikke tar stilling til.
    • Sequence Analysis of the Genome of Piscine Orthoreovirus (PRV) Associated with Heart and Skeletal Muscle Inflammation (HSMI) in Atlantic Salmon (Salmo salar) 

      Markussen, Turhan; Dahle, Maria Krudtaa; Tengs, Torstein; Løvoll, Marie Therese; Finstad, Øystein Wessel; Wiik-Nielsen, Christer R.; Grove, Søren; Lauksund, Reidunn Silje; Robertsen, Børre; Rimstad, Espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Piscine orthoreovirus (PRV) is associated with heart- and skeletal muscle inflammation (HSMI) of farmed Atlantic salmon (Salmo salar). We have performed detailed sequence analysis of the PRV genome with focus on putative encoded proteins, compared with prototype strains from mammalian (MRV T3D)- and avian orthoreoviruses (ARV-138), and aquareovirus (GCRV-873). Amino acid identities were low for ...
    • Eomesodermin of Atlantic Salmon: An Important Regulator of Cytolytic Gene and Interferon Gamma Expression in Spleen Lymphocytes 

      Kumari, Jaya; Bøgwald, Jarl; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Eomesodermin (Eomes), a T-bet homologue expressed in activated CD8+T cells was recently proposed to act as a master regulator of cytotoxic CD8+ T cell effector function and offers an exciting avenue for future exploration. Here, we have identified and characterized the full-length Atlantic salmon Eomes cDNA (2477 bp). Promoter analysis of the salmon Eomes showed the presence of important putative ...
    • Recruitment to the Norwegian fishing fleet: storylines, paradoxes, and pragmatism in Norwegian fisheries and recruitment policy 

      Sønvisen, Signe Annie (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      The majority of actors in the Norwegian fisheries consider recruitment of fishers to be the main future challenge for the Norwegian fishing fleet. As fleet recruitment is a highly politicized field, the problem of how to mitigate the recruitment problem is a subject of heavy debate. Some argue that recruitment problems are caused by low fleet profitability, while others argue that recruitment ...
    • CpG- and LPS-activated MAPK signaling in in vitro cultured salmon (Salmo salar) mononuclear phagocytes 

      Iliev, Dimitri Borisov; Hansen, Tom Egil; Jørgensen, Sven Martin; Krasnov, Aleksei; Jørgensen, Jorunn B (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      The Mitogen-activated protein kinases (MAPK) are involved in transmitting intracellular signals downstream of diverse cell surface receptors and mediate the response to ligands such as growth factors, hormones and cytokines. In addition, MAPK are critically involved in the innate immune response to pathogen-derived substances, commonly referred to as pathogen-associated molecular patterns (PAMPs), ...
    • Farvel til fiskeren? Om frafall og rekruttering til fiske 

      Johnsen, Jahn Petter; Vik, Jostein; Sønvisen, Signe Annie (Chapter; Bokkapittel, 2013)
      Parallelt med tiltagende lukking av de store fiskeriene i Norge, har det skjedd en nedgang i antall fiskere, samtidig som også færre rekrutteres til fiske. Spørsmålet her er om fiskere har blitt skjøvet ut av yrket eller om de har sluttet av andre grunner? En undersøkelse blant fiskere som har sluttet, tyder på at utviklinga i andre næringer og i samfunnet har hatt innvirkning på sysselsettingssystemet ...
    • Aldri mer 18. april! 

      Finstad, Bjørn-Petter; Holm, Petter (Chronicle; Kronikk, 2013-04-18)
      Den 18. april 1989 er et viktig vendepunkt i norsk fiskerihistorie. Det var den dagen Fiskeridepartementet stoppet kystflåtens fiske etter torsk nord for 62. breddegrad - midt i den tradisjonelle sesongen. Reaksjonene lot ikke vente på seg. Historiens første totalforbud mot å fiske torsk var “et sjokk til dyp ettertanke”, het det i Fiskeribladet.