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dc.contributor.authorGarcez, Anderson
dc.contributor.authorWeiderpass, Elisabete
dc.contributor.authorCanuto, Raquel
dc.contributor.authorLecke, Sheila Bünecker
dc.contributor.authorSpritzer, Poli Mara
dc.contributor.authorPattussi, Marcos Pascoal
dc.contributor.authorOlinto, Maria Teresa Anselmo
dc.date.accessioned2018-04-18T09:07:49Z
dc.date.available2018-04-18T09:07:49Z
dc.date.issued2017-05-30
dc.description.abstractObjective: <br> Although the pathogenesis of metabolic syndrome (MetS) is complex and multifactorial, there is limited information if psychological factors, such as stress exposure, are involved in the etiology of MetS. Therefore, this study investigated the associations between MetS and cortisol levels and perceived stress levels among women shift workers in Southern Brazil.<br> Design: <br> A matched case-control study was conducted, including 50 cases of MetS and 200 agematched controls (± 3 yrs, 4 for each case). Salivary cortisol levels were evaluated immediately after waking and one upon returning home from work. Perceived stress levels were measured by the Perceived Stress Scale with 10 items (PSS-10). Multivariate-adjusted associations between MetS and salivary cortisol levels and perceived stress levels were assessed by conditional logistic regression. <br> Results: <br> Means ± standard deviations of salivary cortisol levels were not significantly different between cases and controls either immediately after waking (5.37 ± 4.10 vs. 6.03 ± 5.39 nmol/l; p=0.53) or after work (2.74 ± 2.87 vs. 2.78 ± 2.85 nmol/l; p=0.93). There was no significant difference in perceived stress level between cases and controls (14.2 ± 5.9 vs. 15.5 ± 5.6; p=0.15). No independent association was observed in the multivariate model between MetS and salivary cortisol level or perceived stress level after these exposures were stratified into tertiles. <br> Conclusions: <br> Overall, there was no difference between women with or without MetS in regard to the free salivary cortisol and perceived stress. Our results do not support an association between stress exposure and MetS among women shift workers.en_US
dc.descriptionAccepted manuscript version. Published version available in <a href=http://doi.org/10.1055/s-0043-101822> Hormone and Metabolic Research (2017) 49(7), 510-519. </a>en_US
dc.identifier.citationGarcez, A., Weiderpass, E., Canuto, R., Lecke, S. B., Spritzer, P. M., Pattussi, M. P. & Olinto, M. T. A. (2017). Salivary cortisol, perceived stress, and metabolic syndrome: a matched case-control study in female shift workers. Hormone and Metabolic Research, 49(7), 510-519. http://doi.org/10.1055/s-0043-101822en_US
dc.identifier.cristinIDFRIDAID 1501068
dc.identifier.doi10.1055/s-0043-101822
dc.identifier.issn0018-5043
dc.identifier.issn1439-4286
dc.identifier.urihttps://hdl.handle.net/10037/12540
dc.language.isoengen_US
dc.publisherThieme Publishingen_US
dc.relation.journalHormone and Metabolic Research
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750en_US
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750en_US
dc.titleSalivary cortisol, perceived stress, and metabolic syndrome: a matched case-control study in female shift workersen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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