Show simple item record

dc.contributor.authorFarfaras, Stefanos
dc.contributor.authorEjerhed, Lars Erik
dc.contributor.authorHallström, Erling
dc.contributor.authorHultenby, Kjell
dc.contributor.authorMeknas, Khaled
dc.contributor.authorMovin, Tomas
dc.contributor.authorPapdogiannakis, Nikos
dc.contributor.authorKartus, Jüri Toomas
dc.date.accessioned2018-08-03T12:37:34Z
dc.date.available2018-08-03T12:37:34Z
dc.date.issued2017-03-02
dc.description.abstract<p><i>Purpose</i>: The purpose of the present study was to analyze biopsy samples from the subscapularis tendon and from the joint capsule from male patients with shoulder impingement syndrome (SAIS) and compare them with samples from male patients with post-traumatic recurrent shoulder instability. The hypothesis of the study was that patients with SAIS would have more histologic and ultrastructural degenerative changes in their subscapularis tendon and joint capsule than patients with post-traumatic recurrent shoulder instability.</p> <p><i>Methods</i>: Male patients scheduled for surgery, with either subacromial decompression or Bankart reconstruction, were included. Four biopsies from each patient were obtained from the capsule and four from the subscapularis tendon during arthroscopic surgery. The histologic characteristics and the presence of glycosaminoglycans were assessed using the light microscope, and the ultrastructure was assessed using a transmission electron microscope.</p> <p><i>Results</i>: Eight patients, median age 53 (45–74) years (p < 0.0001), were included in the impingement group, and 12 patients, median age 27 (22–48) years, were included in the instability group. The histologic assessment revealed significantly higher cellularity and total degeneration score in the capsule (p = 0.016 and p = 0.014 respectively) in patients with subacromial impingement compared with the instability patients. The corresponding finding was not made for the subscapularis tendon. The ultrastructural evaluation revealed that the instability patients had more fibrils with a large diameter (indicating less degeneration) in both the subscapularis tendon and the capsule compared with the impingement patients (p < 0.0001).</p> <p><i>Conclusion</i>: Male patients with subacromial impingement have more histologic and ultrastructural degenerative changes in their shoulder compared with patients with post-traumatic recurrent shoulder instability.</p> <p><i>Clinical relevance</i>: It appears that in patients with subacromial impingement, the whole shoulder joint is affected and not only the subacromial space. It is the opinion of the authors that intra-articular therapeutic injections could be tried more often in these patients.</p> <p><i>Level of evidence</i>: III.en_US
dc.descriptionSource at <a href=https://doi.org/10.1007/s00167-017-4442-9> https://doi.org/10.1007/s00167-017-4442-9</a>.en_US
dc.identifier.citationFarfaras, S., Ejerhed, L.E., Hallström, E.K., Hultenby, K., Meknas, K., Movin, T., ... Kartus, J.T. (2017). More histologic and ultrastructural degenerative signs in the subscapularis tendon and the joint capsule in male patients with shoulder impingement. Knee Surgery, Sports Traumatology, Arthroscopy, 26, 79-87. https://doi.org/10.1007/s00167-017-4442-9en_US
dc.identifier.cristinIDFRIDAID 1512501
dc.identifier.doi10.1007/s00167-017-4442-9
dc.identifier.issn0942-2056
dc.identifier.issn1433-7347
dc.identifier.urihttps://hdl.handle.net/10037/13349
dc.language.isoengen_US
dc.publisherSpringer Verlag (Germany)en_US
dc.relation.journalKnee Surgery, Sports Traumatology, Arthroscopy
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Ortopedisk kirurgi: 784en_US
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Orthopedic surgery: 784en_US
dc.subjectSubacromial impingement en_US
dc.subjectShoulder instability en_US
dc.subjectBiopsy en_US
dc.subjectSubscapularis tendon en_US
dc.subjectShoulder joint capsule en_US
dc.subjectDegenerationen_US
dc.titleMore histologic and ultrastructural degenerative signs in the subscapularis tendon and the joint capsule in male patients with shoulder impingementen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


File(s) in this item

Thumbnail

This item appears in the following collection(s)

Show simple item record