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dc.contributor.advisorAl-Haroni, Mohammed
dc.contributor.authorJohansen, Stine Dolores Arctander
dc.contributor.authorHansen, Ragnhild Tanberg
dc.contributor.authorRessheim, Tina-Beate Grønning
dc.date.accessioned2019-06-08T11:27:18Z
dc.date.available2019-06-08T11:27:18Z
dc.date.issued2016-05-19
dc.description.abstractDental infections are getting more difficult to treat because of the increasing amount of antibiotic resistant oral bacteria. A bacterium can acquire resistance by horizontal gene transfer, this allows a bacterial population to acquire antibiotic resistance genes at a great rate. Occasionally, newly acquired resistance can reduce bacterial fitness. However, bacteria can evolve quickly to compensate for any fitness loss. Mobile genetic elements are genetic elements capable of translocation in the same genome, or move between bacterial species or cross bacterial populations. Mobile genetic elements are important from a clinical point of view because they can mediate the transfer of antibiotic resistance. Tn916 is a type of mobile genetic element which can be transferred into a wide range of bacterial phyla. This study aimed to investigate the fitness cost of newly acquired Tn916 in Enterococcus faecium through investigation of growth curves of different strains of E. faecium with and without Tn916. This study will also investigate the excision rate of Tn916, using ddPCR.en_US
dc.identifier.urihttps://hdl.handle.net/10037/15487
dc.language.isoengen_US
dc.publisherUiT Norges arktiske universiteten_US
dc.publisherUiT The Arctic University of Norwayen_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2016 The Author(s)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/3.0en_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)en_US
dc.subject.courseIDODO-3901
dc.subjectVDP::Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710en_US
dc.subjectVDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710en_US
dc.titleFitness cost and excision rate of the conjugative transposon Tn916en_US
dc.typeMaster thesisen_US
dc.typeMastergradsoppgaveen_US


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Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)