Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana
Permanent lenke
https://hdl.handle.net/10037/16904Åpne
Accepted manuscript version (PDF)
Supplementary information (PDF)
Dato
2019-02-20Type
Journal articleTidsskriftartikkel
Peer reviewed
Forfatter
Michael Siranjeevi, Raja Priyanka Mary; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer; Østnes Hansen, KineSammendrag
The new guanidine alkaloid Dendrobeaniamine A (1) was isolated from the organic extract of the Arctic marine bryozoan Dendrobeania murrayana. The chemical structure of 1 was elucidated by spectroscopic experiments, including 1D and 2D NMR and HRESIMS analysis. Compound 1 is a lipoamino acid, consisting of a C12 fatty acid anchored to the amino acid arginine. The bioactivity of 1 was evaluated using cellular and biochemical assays, but the compound did not show cytotoxic, antimicrobial, anti-inflammatory or antioxidant activities
Beskrivelse
This is an Accepted Manuscript of an article published by Taylor & Francis in Natural Product Research on 20 February 2019, available online: https://www.tandfonline.com/doi/full/10.1080/14786419.2019.1574788.