Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana

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https://hdl.handle.net/10037/16904
DOI
https://doi.org/10.1080/14786419.2019.1574788
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Date
2019-02-20
Type
Journal article
Tidsskriftartikkel
Peer reviewed

Author
Michael Siranjeevi, Raja Priyanka Mary; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer; Østnes Hansen, Kine
Abstract
The new guanidine alkaloid Dendrobeaniamine A (1) was isolated from the organic extract of the Arctic marine bryozoan Dendrobeania murrayana. The chemical structure of 1 was elucidated by spectroscopic experiments, including 1D and 2D NMR and HRESIMS analysis. Compound 1 is a lipoamino acid, consisting of a C12 fatty acid anchored to the amino acid arginine. The bioactivity of 1 was evaluated using cellular and biochemical assays, but the compound did not show cytotoxic, antimicrobial, anti-inflammatory or antioxidant activities
Description
This is an Accepted Manuscript of an article published by Taylor & Francis in Natural Product Research on 20 February 2019, available online: https://www.tandfonline.com/doi/full/10.1080/14786419.2019.1574788.
Is part of
Michael, P. (2019). Isolation and Charecterization of New secondary metabolites from the Arctic Bryozoans Securiflustra securifrons and Dendrobeania murrayana. (Doctoral thesis). https://hdl.handle.net/10037/15918.
Publisher
Taylor & Francis
Citation
Michael Siranjeevi RPM, Hansen E, Isaksson J, Andersen Jh, Østnes Hansen KØ. Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana. Natural Product Research. 2019
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