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dc.contributor.authorChen, Gang
dc.contributor.authorOlsen, Jan Abel
dc.date.accessioned2020-12-21T09:21:21Z
dc.date.available2020-12-21T09:21:21Z
dc.date.issued2020-07-09
dc.description.abstract<i>Purpose</i> - The EQ-5D is the most widely applied generic preference-based measure (GPBM) of health-related quality of life (HRQoL). Much concern has been raised that its descriptive system is lacking psycho-social dimensions. A recent paper in this journal provided theoretical support for four dimensions to fill this gap. The current paper aims to provide empirical support for these suggested bolt-on dimensions to the EQ-5D.<p> <p>Methods</i> - We use data from the comprehensive Multi-Instrument-Comparison (MIC) study. The four proposed bolt-on dimensions (Vitality, Sleep, Social Relationships, and Community Connectedness) were selected from the Assessment of Quality of Life (AQoL)-8D. We investigate the relative importance of these four dimensions as compared to the five EQ-5D-5L dimensions on explaining HRQoL (measured by a visual analogue scale; <i>N</i> = 7846) or global life satisfaction (measured by the Satisfaction With Life Scale; <i>N</i> = 8005), using the Shorrocks-Shapely decomposition analysis. Robustness analyses on Vitality was conducted using data from the United States National Health Measurement Study (NHMS) (<i>N</i> = 3812).<p> <p><i>Results</i> - All five EQ-5D-5L dimensions and four bolt-on dimensions significantly explained the variance of HRQoL. Among them, Vitality was found to be the most important dimension with regard to the HRQoL (relative contribution based on the Shorrocks-Shapely decomposition of R<sup>2</sup>: 23.0%), followed by Usual Activities (15.1%). Self-Care was the least important dimension (relative contribution: 5.4%). As a comparison, when explaining global life satisfaction, Social Relationships was the most important dimension (relative contribution: 24.0%), followed by Anxiety/Depression (23.2%), while Self-Care remained the least important (relative contribution: 1.6%). The importance of the Vitality dimension in explaining HRQoL was supported in the robustness analysis using the NHMS data (relative contribution: 23.7%).<p> <p><i>Conclusions</i> - We provide empirical support for complementing the current EQ-5D-5L descriptive system with a coherent set of four bolt-on dimensions that will fill its psycho-social gap. Such an extended health state classification system would in particular be relevant for programme evaluations within the expanding fields of mental health and community care.en_US
dc.identifier.citationChen, Olsen. Filling the psycho-social gap in the EQ-5D: the empirical support for four bolt-on dimensions. Quality of Life Research. 2020:1-11en_US
dc.identifier.cristinIDFRIDAID 1820332
dc.identifier.doi10.1007/s11136-020-02576-5
dc.identifier.issn0962-9343
dc.identifier.issn1573-2649
dc.identifier.urihttps://hdl.handle.net/10037/20105
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.relation.journalQuality of Life Research
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2020 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en_US
dc.titleFilling the psycho-social gap in the EQ-5D: the empirical support for four bolt-on dimensionsen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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